| Correlation of TBX21 gene polymorphisms with ankylosing spondylitis in a Chinese population. | Correlation of TBX21 gene polymorphisms with ankylosing spondylitis in a Chinese population.
Li L, Shan J, Fang H, An G, Zhang M, Zhou P, Xie K, Jin B, Zhu H, Jin X, Yang P, Du L. | 07/9/2024 |
| Evaluation of the presence of Th1 response through T-bet and IFN-gamma immunohistochemical expression in lower lip and oral tongue squamous cell carcinomas. | Evaluation of the presence of Th1 response through T-bet and IFN-gamma immunohistochemical expression in lower lip and oral tongue squamous cell carcinomas.
Rodrigues RR, Freitas VS, Alves PM, Almeida Freitas R, Souza LB, Andrade Santos PP. | 01/29/2024 |
| TBX21 attenuates colorectal cancer progression via an ARHGAP29/RSK/GSK3beta dependent manner. | TBX21 attenuates colorectal cancer progression via an ARHGAP29/RSK/GSK3β dependent manner.
Jiang X, Du W, Yang C, Wang S, Li Y, Shen X, Yang X, Yao J, Du R, Zhang X, Huang Y, Shen W. | 12/1/2023 |
| T-BET and EOMES sustain mature human NK cell identity and antitumor function. | T-BET and EOMES sustain mature human NK cell identity and antitumor function.
Wong P, Foltz JA, Chang L, Neal CC, Yao T, Cubitt CC, Tran J, Kersting-Schadek S, Palakurty S, Jaeger N, Russler-Germain DA, Marin ND, Gang M, Wagner JA, Zhou AY, Jacobs MT, Foster M, Schappe T, Marsala L, McClain E, Pence P, Becker-Hapak M, Fisk B, Petti AA, Griffith OL, Griffith M, Berrien-Elliott MM, Fehniger TA., Free PMC Article | 07/6/2023 |
| Expression analysis of IL-2, TBX21 and SOCS1 in peripheral blood cells of celiac disease patients reveals the diagnostic potential of IL-2. | Expression analysis of IL-2, TBX21 and SOCS1 in peripheral blood cells of celiac disease patients reveals the diagnostic potential of IL-2.
Ganjali F, Asri N, Rostami-Nejad M, Hashemi M, Ainy E, Masotti A, Asadzadeh Aghdaei H. | 05/28/2023 |
| Association of TBX21 gene polymorphisms and acute anterior uveitis risk in a Chinese population: A case-control study. | Association of TBX21 gene polymorphisms and acute anterior uveitis risk in a Chinese population: A case-control study.
Shan J, Li L, Du L, Yang P. | 03/28/2023 |
| The expansion of human T-bet(high)CD21(low) B cells is T cell dependent. | The expansion of human T-bet(high)CD21(low) B cells is T cell dependent.
Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K. | 03/12/2022 |
| The Th1 cell regulatory circuitry is largely conserved between human and mouse. | The Th1 cell regulatory circuitry is largely conserved between human and mouse.
Henderson S, Pullabhatla V, Hertweck A, de Rinaldis E, Herrero J, Lord GM, Jenner RG., Free PMC Article | 01/29/2022 |
| SARS-CoV-2 spike-specific memory B cells express higher levels of T-bet and FcRL5 after non-severe COVID-19 as compared to severe disease. | SARS-CoV-2 spike-specific memory B cells express higher levels of T-bet and FcRL5 after non-severe COVID-19 as compared to severe disease.
Reyes RA, Clarke K, Gonzales SJ, Cantwell AM, Garza R, Catano G, Tragus RE, Patterson TF, Bol S, Bunnik EM., Free PMC Article | 01/29/2022 |
| T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells. | T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells.
Kiekens L, Van Loocke W, Taveirne S, Wahlen S, Persyn E, Van Ammel E, De Vos Z, Matthys P, Van Nieuwerburgh F, Taghon T, Van Vlierberghe P, Vandekerckhove B, Leclercq G., Free PMC Article | 12/25/2021 |
| Association of the rs17250932, rs4794067, and rs2240017 polymorphism in the TBX21 gene with autoimmune diseases: A meta-analysis. | Association of the rs17250932, rs4794067, and rs2240017 polymorphism in the TBX21 gene with autoimmune diseases: A meta-analysis.
Wang HL, Wang H, Wu Y, Ling HY, Wu LL, Ye DQ, Wang B. | 11/22/2021 |
| Role of the IL-23-T-bet/GATA3 Axis for the Pathogenesis of Ulcerative Colitis. | Role of the IL-23-T-bet/GATA3 Axis for the Pathogenesis of Ulcerative Colitis.
Ogino H, Fukaura K, Iboshi Y, Nagamatsu Y, Okuno H, Nishioka K, Nishihara Y, Tanaka Y, Chinen T, Ihara E, Ogawa Y. | 11/13/2021 |
| High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency. | High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency.
Yang R, Weisshaar M, Mele F, Benhsaien I, Dorgham K, Han J, Croft CA, Notarbartolo S, Rosain J, Bastard P, Puel A, Fleckenstein B, Glimcher LH, Di Santo JP, Ma CS, Gorochov G, Bousfiha A, Abel L, Tangye SG, Casanova JL, Bustamante J, Sallusto F., Free PMC Article | 11/6/2021 |
| T-bet Expression in Peripheral Th17.0 Cells Is Associated With Pulmonary Function Changes in Sarcoidosis. | T-bet Expression in Peripheral Th17.0 Cells Is Associated With Pulmonary Function Changes in Sarcoidosis.
Arger NK, Machiraju S, Allen IE, Woodruff PG, Koth LL., Free PMC Article | 04/13/2021 |
| Tbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis. | Tbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis.
Di Giovangiulio M, Rizzo A, Franzè E, Caprioli F, Facciotti F, Onali S, Favale A, Stolfi C, Fehling HJ, Monteleone G, Fantini MC., Free PMC Article | 10/24/2020 |
| Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation. | Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation.
Austin JW, Buckner CM, Kardava L, Wang W, Zhang X, Melson VA, Swanson RG, Martins AJ, Zhou JQ, Hoehn KB, Fisk JN, Dimopoulos Y, Chassiakos A, O'Dell S, Smelkinson MG, Seamon CA, Kwan RW, Sneller MC, Pittaluga S, Doria-Rose NA, McDermott A, Li Y, Chun TW, Kleinstein SH, Tsang JS, Petrovas C, Moir S., Free PMC Article | 09/12/2020 |
| Protein levels of T-bet were downregulated in PBMCs from acute gout patients. | Downregulation of Transcription Factor T-Bet as a Protective Strategy in Monosodium Urate-Induced Gouty Inflammation.
Yang QB, He YL, Zhang QB, Mi QS, Zhou JG., Free PMC Article | 07/25/2020 |
| T-bet and IgG3 are the regulators of B-cell function in chronic HIV-1 viremia. [review] | B-cell abnormalities in HIV-1 infection: roles for IgG3 and T-bet.
Kardava L, Moir S., Free PMC Article | 06/13/2020 |
| The single nucleotide polymorphisms (SNPs) rs4794067, rs2275806, rs2232365, and rs3761548 map in the genes of TBX21, GATA3, and FOXP3 were investigated if they are associated with acute cellular liver transplant rejection. | Impact of TBX21, GATA3, and FOXP3 gene polymorphisms on acute cellular rejection after liver transplantation.
Thude H, Tiede P, Sterneck M, Nashan B, Koch M. | 05/16/2020 |
| the identification of pathways that can increase the function of T-bet in activating Tregs and inducing angiogenesis might be used as a new therapeutic option in future investigations. | T-bet transcription factor in cardiovascular disease: Attenuation or inflammation factor?
Haybar H, Rezaeeyan H, Shahjahani M, Shirzad R, Saki N. | 04/11/2020 |
| our study identified three mRNAs (TBX21, TGIF2, and CYCS) that were significantly altered between high- and low-risk patients with breast cancer. The three-mRNA model was independent and predicted the prognosis of patients robustly. Furthermore, this model could predict survival probability precisely in patients with or without metastasis. | Three inflammation-related genes could predict risk in prognosis and metastasis of patients with breast cancer.
Zhao S, Shen W, Du R, Luo X, Yu J, Zhou W, Dong X, Gao R, Wang C, Yang H, Wang S., Free PMC Article | 03/28/2020 |
| findings reveal that a high frequency of Eomes(+)T-bet(low) CD8(+) T cells predicts poor clinical outcome in acute myeloid leukemia (AML) and that targeting Eomes may provide a therapeutic benefit against AML | Eomes(+)T-bet(low) CD8(+) T Cells Are Functionally Impaired and Are Associated with Poor Clinical Outcome in Patients with Acute Myeloid Leukemia.
Jia B, Zhao C, Rakszawski KL, Claxton DF, Ehmann WC, Rybka WB, Mineishi S, Wang M, Shike H, Bayerl MG, Sivik JM, Schell TD, Drabick JJ, Hohl RJ, Zheng H. | 01/4/2020 |
| Decreased IFNgamma expression plus T-bet down-regulation suggested the inhibitory effect of menthol on Th1 cells differentiation and hence imply its possible therapeutic usefulness in inflammatory diseases. | Inhibition of interferon-γ production and T-bet expression by menthol treatment of human peripheral blood mononuclear cells.
Bayat M, Kalantar K, Amirghofran Z. | 12/7/2019 |
| OS was significantly improved for patients with high T-bet-expressing TILs in TNBC. Thus, T-bet may be a predictive indicator for survival and various immunotherapy strategies in TNBC. | T-bet(+) lymphocytes infiltration as an independent better prognostic indicator for triple-negative breast cancer.
Mori H, Kubo M, Kai M, Yamada M, Kurata K, Kawaji H, Kaneshiro K, Osako T, Nishimura R, Arima N, Okido M, Kishimoto J, Oda Y, Nakamura M., Free PMC Article | 12/7/2019 |
| the TBX21-1993 T allele and TC/CC genotypes predispose to Th1-type immune response development in vitro, influence immune response polarization in vivo, and consequently account for the risk for apical periodontitis development. | TBX21-1993T/C polymorphism association with Th1 and Th17 response at periapex and with periapical lesions development risk.
Colavite PM, Cavalla F, Garlet TP, Azevedo MCS, Melchiades JL, Campanelli AP, Letra A, Trombone APF, Silva RM, Garlet GP. | 10/19/2019 |