| Interleukin-17A educated hepatic stellate cells promote hepatocellular carcinoma occurrence through fibroblast activation protein expression. | Interleukin-17A educated hepatic stellate cells promote hepatocellular carcinoma occurrence through fibroblast activation protein expression.
Ni JS, Fu SY, Wang ZY, Ding WB, Huang J, Guo XG, Gu FM. | 07/11/2024 |
| Interleukin 17A Contributes to Blood-Brain Barrier Disruption of Hypothalamic Paraventricular Nucleus in Rats With Myocardial Infarction. | Interleukin 17A Contributes to Blood-Brain Barrier Disruption of Hypothalamic Paraventricular Nucleus in Rats With Myocardial Infarction.
Yu Y, Weiss RM, Wei SG., Free PMC Article | 02/8/2024 |
| Prenatal caffeine exposure induces autism-like behaviors in offspring under a high-fat diet via the gut microbiota-IL-17A-brain axis. | Prenatal caffeine exposure induces autism-like behaviors in offspring under a high-fat diet via the gut microbiota-IL-17A-brain axis.
Wang T, Zhang S, Luo M, Lu M, Wei L, Zhou X, Wang H, Xu D. | 02/1/2024 |
| HDAC2 exacerbates rheumatoid arthritis progression via the IL-17-CCL7 signaling pathway. | HDAC2 exacerbates rheumatoid arthritis progression via the IL-17-CCL7 signaling pathway.
Mao D, Jiang H, Zhang F, Yang H, Fang X, Zhang Q, Zhao G. | 06/23/2023 |
| Mechanism of Catechol-O-methyltransferase Regulating Orofacial Pain Induced by Tooth Movement. | Mechanism of Catechol-O-methyltransferase Regulating Orofacial Pain Induced by Tooth Movement.
Zhou Y, Song Z, Chen S, Yao F, Liu J, Ouyang Z, Liao Z., Free PMC Article | 01/22/2022 |
| Pathogenic Characteristics of Th17 Cells Based on the IL-17 Signaling Pathway in the Regulation of Sebaceous Gland Lipoprotein Metabolism in an Acne Rat Model. | Pathogenic Characteristics of Th17 Cells Based on the IL-17 Signaling Pathway in the Regulation of Sebaceous Gland Lipoprotein Metabolism in an Acne Rat Model.
He Y, Yang Q, Zhang T, Zeng Y, Du L, Zhang C, Wang W. | 01/22/2022 |
| Interleukin-17 induces hypertension but does not impair cerebrovascular function in pregnant rats. | Interleukin-17 induces hypertension but does not impair cerebrovascular function in pregnant rats.
Duncan JW, Nemeth Z, Hildebrandt E, Granger JP, Ryan MJ, Drummond HA., Free PMC Article | 11/13/2021 |
| [Effect of electroacupuncture on expression of IL-23/IL-17 axis and TLR4 in infarcted tissue in rats with myocardial infarction]. | [Effect of electroacupuncture on expression of IL-23/IL-17 axis and TLR4 in infarcted tissue in rats with myocardial infarction].
Sun K, Wu JH, Bai H, Xu SL, Xia XF, Liu YC, Lu SF, Gu YH, Zhang HR. | 09/25/2021 |
| In situ Evidence of Collagen V and Interleukin-6/Interleukin-17 Activation in Vascular Remodeling of Experimental Pulmonary Hypertension. | In situ Evidence of Collagen V and Interleukin-6/Interleukin-17 Activation in Vascular Remodeling of Experimental Pulmonary Hypertension.
Batah SS, Alda MA, Rodrigues Lopes Roslindo Figueira R, Cruvinel HR, Perdoná Rodrigues da Silva L, Machado-Rugolo J, Velosa AP, Teodoro WR, Balancin M, Silva PL, Capelozzi VL, Fabro AT. | 07/17/2021 |
| Excessive Reactive Oxygen Species Inhibit IL-17A(+) gammadelta T Cells and Innate Cellular Responses to Bacterial Lung Infection. | Excessive Reactive Oxygen Species Inhibit IL-17A(+) γδ T Cells and Innate Cellular Responses to Bacterial Lung Infection.
Anthony D, Papanicolaou A, Wang H, Seow HJ, To EE, Yatmaz S, Anderson GP, Wijburg O, Selemidis S, Vlahos R, Bozinovski S. | 07/10/2021 |
| [Effect of different orthodontic forces on the expression of T helper cell 17 cell-related cytokines in the pressure side of periodontal tissue in rats]. | [Effect of different orthodontic forces on the expression of T helper cell 17 cell-related cytokines in the pressure side of periodontal tissue in rats].
Wang LY, Wang B, Cong BB, Cui T, Du YQ, Song Y., Free PMC Article | 04/17/2021 |
| IL-17a exacerbates hepatic ischemia-reperfusion injury in fatty liver by promoting neutrophil infiltration and mitochondria-driven apoptosis. | IL-17a exacerbates hepatic ischemia-reperfusion injury in fatty liver by promoting neutrophil infiltration and mitochondria-driven apoptosis.
Yang X, Li C, Ng KT, Liu J, Liu H, Zhang W, Xiao F, Li X, Lo CM, Lu L, Man K. | 02/13/2021 |
| IL-17A exacerbates neuroinflammation and neurodegeneration by activating microglia in rodent models of Parkinson's disease. | IL-17A exacerbates neuroinflammation and neurodegeneration by activating microglia in rodent models of Parkinson's disease.
Liu Z, Qiu AW, Huang Y, Yang Y, Chen JN, Gu TT, Cao BB, Qiu YH, Peng YP. | 08/15/2020 |
| nterleukin 17 is an important pathogenicity gene in pediatric sepsis. | Interleukin 17 is an important pathogenicity gene in pediatric sepsis.
Han Y, Li X, Gao S, Liu X, Kang L, Li X, Lang Y, Li X, Sun M, Gai Z, Yu S. | 06/20/2020 |
| interleukin 17 is involved in spatio-temporal inflammation induced by benzalkonium chloride. | Correlation of spatio-temporal characteristics of intestinal inflammation with IL-17 in a rat model of hypoganglionosis.
Yu H, Cao NJ, Pan WK, Su L, Zhao YY, Tian DH, Xu WY, Gao Y, Zheng BJ. | 05/18/2019 |
| Bacterial overgrowth associated with bacterial translocation is linked to intestinal over-expression of IFN-gamma, IL-4, IL-17 and mucin-2 in cholestasis. | Bacterial Translocation Is Linked to Increased Intestinal IFN-γ, IL-4, IL-17, and mucin-2 in Cholestatic Rats.
Vega-Magaña N, Delgado-Rizo V, García-Benavides L, Del Toro-Arreola S, Segura-Ortega J, Morales ASMZ, Zepeda-Nuño JS, Escarra-Senmarti M, Gutiérrez-Franco J, Haramati J, Bueno-Topete MR. | 04/27/2019 |
| involved in the development of intestinal fibrosis through inducing epithelial-mesenchymal transition | IL-17A Promotes Initiation and Development of Intestinal Fibrosis Through EMT.
Zhang HJ, Zhang YN, Zhou H, Guan L, Li Y, Sun MJ. | 04/20/2019 |
| In a rat traumatc brain injury model, levels of IL-17 increased from 6 h to 7 days and peaked at 3 days, in both the CNS and serum, which were consistent with the severity of secondary brain injury. Suberoylanilide hydroxamic acid treatment decreased the expressions of IL-17, reduced neuronal apoptosis, and improved neural function, suggesting that IL-17 is involved in secondary brain injury after TBI. | Involvement of IL-17 in Secondary Brain Injury After a Traumatic Brain Injury in Rats.
Li T, Zhang YM, Han D, Hua R, Guo BN, Hu SQ, Yan XL, Xu T. | 07/21/2018 |
| In both the high-glucose - treated Muller cells and Akita mouse retina, the Act1/TRAF6/IKK/NF-kappaB signaling pathway was activated. IL-17A further enhanced inflammatory signaling activation, whereas Act1 knockdown or IKK inhibition blocked the downstream signaling activation by IL-17A. | IL-17A exacerbates diabetic retinopathy by impairing Müller cell function via Act1 signaling.
Qiu AW, Bian Z, Mao PA, Liu QH., Free PMC Article | 11/26/2017 |
| Study highlighted the contribution of IL-17 pathway in the trafficking of CXCL13-induced GluN2B-containing N-methyl-d-aspartate receptor in the pathogenesis of remifentanil-induced hyperalgesia. | CXCL13 regulates the trafficking of GluN2B-containing NMDA receptor via IL-17 in the development of remifentanil-induced hyperalgesia in rats.
Zhu M, Yuan ST, Yu WL, Jia LL, Sun Y. | 11/11/2017 |
| In conclusion, NSun2 mediates HHcy-induced upregulation of IL-17A expression by methylating IL-17A mRNA and promoting its translation in T lymphocytes. | Homocysteine upregulates interleukin-17A expression via NSun2-mediated RNA methylation in T lymphocytes.
Wang N, Tang H, Wang X, Wang W, Feng J. | 10/28/2017 |
| Local cryotherapy's local and systemic anti-inflammatory effects are mainly IL-6/IL-17A-driven and TNF-alpha independent in the adjuvant-induced arthritis model | Local cryotherapy improves adjuvant-induced arthritis through down-regulation of IL-6 / IL-17 pathway but independently of TNFα.
Guillot X, Martin H, Seguin-Py S, Maguin-Gaté K, Moretto J, Totoson P, Wendling D, Demougeot C, Tordi N., Free PMC Article | 10/21/2017 |
| RORgamma/IL-17A axis influences VEGF production and neovascular retinopathy by mechanisms involving neuroglia. Inhibition of RORgamma and IL-17A may have potential for the improved treatment of neovascular retinopathies. | Inhibition of the Nuclear Receptor RORγ and Interleukin-17A Suppresses Neovascular Retinopathy: Involvement of Immunocompetent Microglia.
Talia DM, Deliyanti D, Agrotis A, Wilkinson-Berka JL. | 06/24/2017 |
| Results from the present study indicate that IL17 may contribute to neuropathic pain by promoting the proliferation of astrocytes and secretion of proinflammatory cytokines in spinal nerve ligationinduced neuropathic pain. | IL-17 contributed to the neuropathic pain following peripheral nerve injury by promoting astrocyte proliferation and secretion of proinflammatory cytokines.
Sun C, Zhang J, Chen L, Liu T, Xu G, Li C, Yuan W, Xu H, Su Z., Free PMC Article | 04/1/2017 |
| Results suggest that, via astrocytes, IL-17A could promote glutamate excitotoxicity in multiple terms: by decreasing the astrocyte ability to uptake extracellular glutamate, due to a reduced gene expression of glutamate transporters (GLAST and GLT-1); by decreasing intracellular glutamate conversion into non-toxic glutamine; by potentiating glutamate exocytosis in a Ca2+ dependent manner | IL-17 signalling in astrocytes promotes glutamate excitotoxicity: Indications for the link between inflammatory and neurodegenerative events in multiple sclerosis.
Kostic M, Zivkovic N, Cvetanovic A, Stojanovic I, Colic M. | 03/4/2017 |