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    N Notch [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31293, updated on 17-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Structural requirements for activity of Mind bomb1 in Notch signaling.

    Structural requirements for activity of Mind bomb1 in Notch signaling.
    Cao R, Gozlan O, Airich A, Tveriakhina L, Zhou H, Jiang H, Cole PA, Aster JC, Klein T, Sprinzak D, Blacklow SC.

    10/10/2024
    Dynamic modes of Notch transcription hubs conferring memory and stochastic activation revealed by live imaging the co-activator Mastermind.

    Dynamic modes of Notch transcription hubs conferring memory and stochastic activation revealed by live imaging the co-activator Mastermind.
    DeHaro-Arbona FJ, Roussos C, Baloul S, Townson J, Gómez Lamarca MJ, Bray S., Free PMC Article

    06/27/2024
    Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains.

    Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains.
    Shimizu H, Hosseini-Alghaderi S, Woodcock SA, Baron M., Free PMC Article

    02/16/2024
    Scabrous is distributed via signaling filopodia to modulate Notch response during bristle patterning in Drosophila.

    Scabrous is distributed via signaling filopodia to modulate Notch response during bristle patterning in Drosophila.
    Presser A, Freund O, Hassapelis T, Hunter G., Free PMC Article

    09/25/2023
    TM2D genes regulate Notch signaling and neuronal function in Drosophila.

    TM2D genes regulate Notch signaling and neuronal function in Drosophila.
    Salazar JL, Yang SA, Lin YQ, Li-Kroeger D, Marcogliese PC, Deal SL, Neely GG, Yamamoto S., Free PMC Article

    02/19/2022
    Intermediate progenitor cells provide a transition between hematopoietic progenitors and their differentiated descendants.

    Intermediate progenitor cells provide a transition between hematopoietic progenitors and their differentiated descendants.
    Spratford CM, Goins LM, Chi F, Girard JR, Macias SN, Ho VW, Banerjee U., Free PMC Article

    02/12/2022
    Unraveling the features of somatic transposition in the Drosophila intestine.

    Unraveling the features of somatic transposition in the Drosophila intestine.
    Siudeja K, van den Beek M, Riddiford N, Boumard B, Wurmser A, Stefanutti M, Lameiras S, Bardin AJ., Free PMC Article

    11/6/2021
    A combination of Notch signaling, preferential adhesion and endocytosis induces a slow mode of cell intercalation in the Drosophila retina.

    A combination of Notch signaling, preferential adhesion and endocytosis induces a slow mode of cell intercalation in the Drosophila retina.
    Blackie L, Tozluoglu M, Trylinski M, Walther RF, Schweisguth F, Mao Y, Pichaud F., Free PMC Article

    10/9/2021
    Membrane-Anchored Hairless Protein Restrains Notch Signaling Activity.

    Membrane-Anchored Hairless Protein Restrains Notch Signaling Activity.
    Maier D., Free PMC Article

    07/31/2021
    The Clathrin adaptor AP-1 and Stratum act in parallel pathways to control Notch activation in Drosophila sensory organ precursors cells.

    The Clathrin adaptor AP-1 and Stratum act in parallel pathways to control Notch activation in Drosophila sensory organ precursors cells.
    Bellec K, Pinot M, Gicquel I, Le Borgne R., Free PMC Article

    04/24/2021
    Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism.

    Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism.
    Kuang Y, Golan O, Preusse K, Cain B, Christensen CJ, Salomone J, Campbell I, Okwubido-Williams FV, Hass MR, Yuan Z, Eafergan N, Moberg KH, Kovall RA, Kopan R, Sprinzak D, Gebelein B., Free PMC Article

    04/3/2021
    The Impact of Drosophila Awd/NME1/2 Levels on Notch and Wg Signaling Pathways.

    The Impact of Drosophila Awd/NME1/2 Levels on Notch and Wg Signaling Pathways.
    Serafini G, Giordani G, Grillini L, Andrenacci D, Gargiulo G, Cavaliere V., Free PMC Article

    03/6/2021
    Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD.

    Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD.
    Li S, Wu Z, Tantray I, Li Y, Chen S, Dong J, Glynn S, Vogel H, Snyder M, Lu B., Free PMC Article

    11/28/2020
    Making sense out of missense mutations: Mechanistic dissection of Notch receptors through structure-function studies in Drosophila.

    Making sense out of missense mutations: Mechanistic dissection of Notch receptors through structure-function studies in Drosophila.
    Yamamoto S., Free PMC Article

    10/10/2020
    Maternal almondex, a neurogenic gene, is required for proper subcellular Notch distribution in early Drosophila embryogenesis.

    Maternal almondex, a neurogenic gene, is required for proper subcellular Notch distribution in early Drosophila embryogenesis.
    Das P, Salazar JL, Li-Kroeger D, Yamamoto S, Nakamura M, Sasamura T, Inaki M, Masuda W, Kitagawa M, Yamakawa T, Matsuno K.

    10/10/2020
    Sequential activation of Notch and Grainyhead gives apoptotic competence to Abdominal-B expressing larval neuroblasts in Drosophila Central nervous system.

    Sequential activation of Notch and Grainyhead gives apoptotic competence to Abdominal-B expressing larval neuroblasts in Drosophila Central nervous system.
    Bakshi A, Sipani R, Ghosh N, Joshi R., Free PMC Article

    09/26/2020
    Drosophila Neuroblast Selection Is Gated by Notch, Snail, SoxB, and EMT Gene Interplay.

    Drosophila Neuroblast Selection Is Gated by Notch, Snail, SoxB, and EMT Gene Interplay.
    Arefin B, Parvin F, Bahrampour S, Stadler CB, Thor S.

    09/26/2020
    Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila.

    Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila.
    Pandey A, Harvey BM, Lopez MF, Ito A, Haltiwanger RS, Jafar-Nejad H., Free PMC Article

    09/19/2020
    A novel mode of regulation of Notch signaling by the chromatin-modeling protein Htk.

    Regulation of Notch signaling by the chromatin-modeling protein Hat-trick.
    Singh A, Paul MS, Dutta D, Mutsuddi M, Mukherjee A.

    07/11/2020
    Employ genome engineering to generate a functional optogenetic allele of the Notch ligand Delta (opto-Delta), which replaces both copies of the endogenous wild-type locus. Using clonal analysis, we show that optogenetic activation blocks Notch activation through cis-inhibition in signal-receiving cells.

    Optogenetic inhibition of Delta reveals digital Notch signalling output during tissue differentiation.
    Viswanathan R, Necakov A, Trylinski M, Harish RK, Krueger D, Esposito E, Schweisguth F, Neveu P, De Renzis S., Free PMC Article

    05/23/2020
    ch-responsive enhancers are activated synchronously in Drosophila embryos; Priming by Twist and Dorsal promotes fast and sustained response to Notch

    Enhancer Priming Enables Fast and Sustained Transcriptional Responses to Notch Signaling.
    Falo-Sanjuan J, Lammers NC, Garcia HG, Bray SJ., Free PMC Article

    05/16/2020
    Data show separable and cell-type-specific functions of Groucho (Gro) and C-terminal binding protein (CtBP) in a Notch signaling cascade involved lateral inhibition process.

    Division of Labor: Roles of Groucho and CtBP in Notch-Mediated Lateral Inhibition that Controls Intestinal Stem Cell Differentiation in Drosophila.
    Guo X, Huang H, Yang Z, Cai T, Xi R., Free PMC Article

    05/2/2020
    Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling.

    Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling.
    Zacharioudaki E, Falo Sanjuan J, Bray S., Free PMC Article

    04/11/2020
    REVIEW: Insulin-dependent Non-canonical Activation of Notch in Drosophila: A Story of Notch-Induced Muscle Stem Cell Proliferation

    Insulin-dependent Non-canonical Activation of Notch in Drosophila: A Story of Notch-Induced Muscle Stem Cell Proliferation.
    Aradhya R, Jagla K.

    03/7/2020
    REVIEW: Role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex in the Regulation of Notch Signaling

    Regulation of Notch Signaling in Drosophila melanogaster: The Role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex.
    Dutta D, Mutsuddi M, Mukherjee A.

    03/7/2020
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