| FOXA3 regulates cholesterol metabolism to compensate for low uptake during the progression of lung adenocarcinoma. | FOXA3 regulates cholesterol metabolism to compensate for low uptake during the progression of lung adenocarcinoma.
Wang D, Cao Y, Meng M, Qiu J, Ni C, Guo X, Li Y, Liu S, Yu J, Guo M, Wang J, Du B, Qiu W, Xie C, Zhao B, Ma X, Cheng X, Xu L., Free PMC Article | 10/31/2024 |
| Whole-exome sequencing identifies FOXL2, FOXA2 and FOXA3 as candidate genes for monogenic congenital anomalies of the kidneys and urinary tract. | Whole-exome sequencing identifies FOXL2, FOXA2 and FOXA3 as candidate genes for monogenic congenital anomalies of the kidneys and urinary tract.
Zheng B, Seltzsam S, Wang C, Schierbaum L, Schneider S, Wu CW, Dai R, Connaughton DM, Nakayama M, Mann N, Stajic N, Mane S, Bauer SB, Tasic V, Nam HJ, Shril S, Hildebrandt F., Free PMC Article | 10/1/2022 |
| FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls-The GEA Mexican Study. | FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls-The GEA Mexican Study.
Vargas-Alarcón G, Fragoso JM, Ramírez-Bello J, Posadas-Sánchez R., Free PMC Article | 06/11/2022 |
| Transcription factor FOXA3 promotes the development of Hepatoblastoma via regulating HNF1A, AFP, and ZFHX3 expression. | Transcription factor FOXA3 promotes the development of Hepatoblastoma via regulating HNF1A, AFP, and ZFHX3 expression.
Zhan X, Zhao A., Free PMC Article | 11/6/2021 |
| m6A RNA methylation-mediated HNF3gamma reduction renders hepatocellular carcinoma dedifferentiation and sorafenib resistance. | m6A RNA methylation-mediated HNF3γ reduction renders hepatocellular carcinoma dedifferentiation and sorafenib resistance.
Zhou T, Li S, Xiang D, Liu J, Sun W, Cui X, Ning B, Li X, Cheng Z, Jiang W, Zhang C, Liang X, Li L, Cheng X, Hui L, Wang H, Ding J., Free PMC Article | 10/16/2021 |
| Opposing Roles of FoxA1 and FoxA3 in Intrahepatic Cholangiocarcinoma Progression. | Opposing Roles of FoxA1 and FoxA3 in Intrahepatic Cholangiocarcinoma Progression.
Thanan R, Kaewlert W, Sakonsinsiri C, Chaiprasert T, Armartmuntree N, Muengsaen D, Techasen A, Klanrit P, Lert-Itthiporn W, Pinlaor S, Pairojkul C., Free PMC Article | 12/5/2020 |
| Hepatocyte FOXA3 protects against atherosclerosis by inducing ApoA-I and macrophage reverse cholesterol transport. | Hepatic Forkhead Box Protein A3 Regulates ApoA-I (Apolipoprotein A-I) Expression, Cholesterol Efflux, and Atherogenesis.
Li Y, Xu Y, Jadhav K, Zhu Y, Yin L, Zhang Y., Free PMC Article | 02/29/2020 |
| Our study identified novel FOXA3 variants and mutations, assessed the adipogenic capacity of two novel missense alterations in vitro and demonstrated for the first time the associations between FOXA3 SNP rs28666870 with metabolic phenotypes in humans. | Analysis of variants and mutations in the human winged helix FOXA3 gene and associations with metabolic traits.
Adler-Wailes DC, Alberobello AT, Ma X, Hugendubler L, Stern EA, Mou Z, Han JC, Kim PW, Sumner AE, Yanovski JA, Mueller E., Free PMC Article | 05/14/2016 |
| Foxa3 induces goblet cell metaplasia and inhibits innate antiviral immunity in asthma and chronic obstructive pulmonary disease. | Foxa3 induces goblet cell metaplasia and inhibits innate antiviral immunity.
Chen G, Korfhagen TR, Karp CL, Impey S, Xu Y, Randell SH, Kitzmiller J, Maeda Y, Haitchi HM, Sridharan A, Senft AP, Whitsett JA., Free PMC Article | 04/5/2014 |
| In obese subjects, FOXA3 is differentially expressed in visceral and subcutaneous adipose depots. | The winged helix transcription factor Foxa3 regulates adipocyte differentiation and depot-selective fat tissue expansion.
Xu L, Panel V, Ma X, Du C, Hugendubler L, Gavrilova O, Liu A, McLaughlin T, Kaestner KH, Mueller E., Free PMC Article | 10/26/2013 |
| low caloric intake decreases the production of intracellular reactive oxygen species and suppresses endothelial cells senescence through promoting HNF3gamma binging to NOX4 promoter region and inhibiting NOX4 gene expression induced by up-regulated HNF3gamma | [Caloric restriction suppresses endothelial cells senescence via down-regulation of NOX4 induced by HNF3γ].
Liu Q, Li H, Chen HH, Wang J. | 11/24/2012 |
| analysis of the binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells | Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq.
Motallebipour M, Ameur A, Reddy Bysani MS, Patra K, Wallerman O, Mangion J, Barker MA, McKernan KJ, Komorowski J, Wadelius C., Free PMC Article | 08/2/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Genetic predictors of interindividual variability in hepatic CYP3A4 expression.
Lamba V, Panetta JC, Strom S, Schuetz EG., Free PMC Article | 01/20/2010 |
| the HNF-3 site in the fibrinogen beta promoter is important for IL6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism | A hepatocyte nuclear factor-3 site in the fibrinogen beta promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism.
Verschuur M, de Jong M, Felida L, de Maat MP, Vos HL. | 01/21/2010 |