| the same group of dopaminergic neurons also form functional synaptic connections with the anterior paired lateral neurons, thereby emitting a suppressive signal to the latter through Drosophila dopamine 2-like receptor. | Suppression of GABAergic neurons through D2-like receptor secures efficient conditioning in Drosophila aversive olfactory learning.
Zhou M, Chen N, Tian J, Zeng J, Zhang Y, Zhang X, Guo J, Sun J, Li Y, Guo A, Li Y., Free PMC Article | 05/11/2019 |
| By means of genetic mosaicism, we identified widespread dopaminergic modulation within the olfactory circuit that suggests nonredundant and reiterating functions of D2R in support of ARM. Our results oppose ARM to its concomitant memory phases that localize to mushroom bodies and propose a decentralized organization of consolidated ARM. | Circuit Analysis of a Drosophila Dopamine Type 2 Receptor That Supports Anesthesia-Resistant Memory.
Scholz-Kornehl S, Schwärzel M., Free PMC Article | 07/15/2017 |
| The results suggest that fruit flies are an excellent model system to provide some answers to previously unexplainable observations regarding the compromised dopaminergic nervous system and the related therapeutic agents. | Dopamine D2 receptor as a cellular component controlling nocturnal hyperactivities in Drosophila melanogaster.
Lee G, Kikuno K, Bahn JH, Kim KM, Park JH. | 10/26/2013 |
| Our study also showed that rescue of dopaminergic (DA) neurodegeneration by Drosophila DD2R activation was mediated through suppression of action potentials in DA neurons. | Selective degeneration of dopaminergic neurons by MPP(+) and its rescue by D2 autoreceptors in Drosophila primary culture.
Wiemerslage L, Schultz BJ, Ganguly A, Lee D., Free PMC Article | 10/26/2013 |
| It is concluded that the change in the number of DD2Rs in corpus allatum or their activation decreases the fitness of Drosophila. | [The DD2R gene expression level in the corpus allatum affects the fitness of female Drosophila melanogaster].
Raushenbakh IIu, Faddeeva NV, Laukhina OV, Gruntenko NE. | 11/17/2012 |
| mediates, at least in part, the inhibiting effect of dopamine on juvenile hormone synthesis | Downregulation of the dopamine D2-like receptor in corpus allatum affects juvenile hormone synthesis in Drosophila melanogaster females.
Gruntenko NЕ, Laukhina OV, Bogomolova EV, Karpova EK, Menshanov PN, Romanova IV, Rauschenbach IY. | 05/26/2012 |
| role of DD2R in the regulation of juvenile hormone metabolism | The role of D2-like receptors in the regulation of juvenile hormone metabolism in Drosophila females in normal state and at increased dopamine level.
Karpova EK, Gruntenko NE, Shumnaya LV, Romanova IV, Rauschenbach IY. | 11/19/2011 |
| Alkaline phosphatase activity was increased in flies with reduced DD2R expression vs. corresponding controls. | Dopamine down-regulates activity of alkaline phosphatase in Drosophila: the role of D2-like receptors.
Bogomolova EV, Rauschenbach IY, Adonyeva NV, Alekseev AA, Faddeeva NV, Gruntenko NE. | 11/27/2010 |
| Data show that activation of D2-like dopamine receptors inhibits juvenile hormone degradation in female Drosophila. | Activation of D2-like dopamine receptors inhibits young hormone degradation in female Drosophila.
Karpova EK, Rauschenbach IY, Shchumnaya LV, Gruntenko NE. | 09/20/2010 |
| Locomotor activity is regulated by D2-like receptors in Drosophila | Locomotor activity is regulated by D2-like receptors in Drosophila: an anatomic and functional analysis.
Draper I, Kurshan PT, McBride E, Jackson FR, Kopin AS. | 01/21/2010 |
| Molecular characterization and identification of multiple alternatively spliced variants | A Drosophila dopamine 2-like receptor: Molecular characterization and identification of multiple alternatively spliced variants.
Hearn MG, Ren Y, McBride EW, Reveillaud I, Beinborn M, Kopin AS., Free PMC Article | 01/21/2010 |