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    Card9 caspase recruitment domain family, member 9 [ Mus musculus (house mouse) ]

    Gene ID: 332579, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Dissecting the respective roles of microbiota and host genetics in the susceptibility of Card9[-/-] mice to colitis.

    Dissecting the respective roles of microbiota and host genetics in the susceptibility of Card9(-/-) mice to colitis.
    Danne C, Lamas B, Lavelle A, Michel ML, Da Costa G, Pham HP, Lefevre A, Bridonneau C, Bredon M, Planchais J, Straube M, Emond P, Langella P, Sokol H., Free PMC Article

    04/30/2024
    Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses.

    Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses.
    Brandt M, Cao Z, Krishna C, Reedy JL, Gu X, Dutko RA, Oliver BA, Tusi BK, Park J, Richey L, Segerstolpe Å, Litwiler S, Creasey EA, Carey KL, Vyas JM, Graham DB, Xavier RJ., Free PMC Article

    04/3/2024
    Card9/neutrophil signalling axis promotes IL-17A-mediated ankylosing spondylitis.

    Card9/neutrophil signalling axis promotes IL-17A-mediated ankylosing spondylitis.
    Rosenzweig HL, Vance EE, Asare-Konadu K, Koney KV, Lee EJ, Deodhar AA, Sen R, Caplan L, Napier RJ., Free PMC Article

    01/17/2024
    Dectin-1/CARD9 induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-Aspergillus activity in the lung.

    Dectin-1/CARD9 induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-Aspergillus activity in the lung.
    Aufiero MA, Shlezinger N, Gjonbalaj M, Mills KAM, Ballabio A, Hohl TM., Free PMC Article

    11/30/2023
    Macrophage CARD9 mediates cardiac injury following myocardial infarction through regulation of lipocalin 2 expression.

    Macrophage CARD9 mediates cardiac injury following myocardial infarction through regulation of lipocalin 2 expression.
    Liu Y, Shao YH, Zhang JM, Wang Y, Zhou M, Li HQ, Zhang CC, Yu PJ, Gao SJ, Wang XR, Jia LX, Piao CM, Du J, Li YL., Free PMC Article

    11/18/2023
    CARD9 deficiency aggravated nonalcoholic steatohepatitis in mice through increasing inflammatory response.

    CARD9 deficiency aggravated nonalcoholic steatohepatitis in mice through increasing inflammatory response.
    Liu X, Fang Y, Qian C, Chen J, Luo W, Zuo W, Lin J, Xie L, Liang G, Huang L, Wang Y.

    11/16/2023
    CARD9 attenuates Abeta pathology and modifies microglial responses in an Alzheimer's disease mouse model.

    CARD9 attenuates Aβ pathology and modifies microglial responses in an Alzheimer's disease mouse model.
    Ennerfelt H, Holliday C, Shapiro DA, Zengeler KE, Bolte AC, Ulland TK, Lukens JR., Free PMC Article

    06/13/2023
    CARD9 deficiency promotes pancreatic cancer growth by blocking dendritic cell maturation via SLC6A8-mediated creatine transport.

    CARD9 deficiency promotes pancreatic cancer growth by blocking dendritic cell maturation via SLC6A8-mediated creatine transport.
    Tian C, Yuan H, Lu Y, He H, Li Q, Li S, Yang J, Wang M, Xu R, Liu Q, Xiang M., Free PMC Article

    05/15/2023
    CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival.

    CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival.
    Danne C, Michaudel C, Skerniskyte J, Planchais J, Magniez A, Agus A, Michel ML, Lamas B, Da Costa G, Spatz M, Oeuvray C, Galbert C, Poirier M, Wang Y, Lapière A, Rolhion N, Ledent T, Pionneau C, Chardonnet S, Bellvert F, Cahoreau E, Rocher A, Arguello RR, Peyssonnaux C, Louis S, Richard ML, Langella P, El-Benna J, Marteyn B, Sokol H.

    05/10/2023
    [Effects of caspase recruitment domain protein 9 gene knockout on airway inflammation in C57BL/6 mice with steroid resistant asthma].

    [Effects of caspase recruitment domain protein 9 gene knockout on airway inflammation in C57BL/6 mice with steroid resistant asthma].
    Ge XT, Wang MY, Zheng R, Zhang NJ, Zhang YL, Dai YR.

    03/10/2023
    Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis.

    Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis.
    Drummond RA, Desai JV, Hsu AP, Oikonomou V, Vinh DC, Acklin JA, Abers MS, Walkiewicz MA, Anzick SL, Swamydas M, Vautier S, Natarajan M, Oler AJ, Yamanaka D, Mayer-Barber KD, Iwakura Y, Bianchi D, Driscoll B, Hauck K, Kline A, Viall NS, Zerbe CS, Ferré EM, Schmitt MM, DiMaggio T, Pittaluga S, Butman JA, Zelazny AM, Shea YR, Arias CA, Ashbaugh C, Mahmood M, Temesgen Z, Theofiles AG, Nigo M, Moudgal V, Bloch KC, Kelly SG, Whitworth MS, Rao G, Whitener CJ, Mafi N, Gea-Banacloche J, Kenyon LC, Miller WR, Boggian K, Gilbert A, Sincock M, Freeman AF, Bennett JE, Hasbun R, Mikelis CM, Kwon-Chung KJ, Belkaid Y, Brown GD, Lim JK, Kuhns DB, Holland SM, Lionakis MS., Free PMC Article

    11/26/2022
    CARD9 deficiency predisposing chromoblastomycosis: A case report and comparative transcriptome study.

    CARD9 deficiency predisposing chromoblastomycosis: A case report and comparative transcriptome study.
    Huang C, Deng W, Zhang Y, Zhang K, Ma Y, Song Y, Wan Z, Wang X, Li R., Free PMC Article

    10/15/2022
    Card9 protects fungal peritonitis through regulating Malt1-mediated activation of autophagy in macrophage.

    Card9 protects fungal peritonitis through regulating Malt1-mediated activation of autophagy in macrophage.
    Xu Z, Qiao S, Qian W, Zhu Y, Yan W, Shen S, Wang T.

    08/27/2022
    Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages.

    Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages.
    Xu Z, Li D, Qu W, Yin Y, Qiao S, Zhu Y, Shen S, Hou Y, Yang J, Wang T., Free PMC Article

    06/11/2022
    CARD9 Expression Pattern, Gene Dosage, and Immunodeficiency Phenotype Revisited.

    CARD9 Expression Pattern, Gene Dosage, and Immunodeficiency Phenotype Revisited.
    Goel S, Kuehn HS, Chinen J, Niemela J, Stoddard J, Yamanaka D, Garofalo M, Samir S, Migaud M, Oikonomou V, Fleisher T, Puel A, Lionakis MS, Rosenzweig SD., Free PMC Article

    03/12/2022
    Primary Cutaneous Aspergillosis in a Patient with CARD9 Deficiency and Aspergillus Susceptibility of Card9 Knockout Mice.

    Primary Cutaneous Aspergillosis in a Patient with CARD9 Deficiency and Aspergillus Susceptibility of Card9 Knockout Mice.
    Zhang Y, Huang C, Song Y, Ma Y, Wan Z, Zhu X, Wang X, Li R.

    01/22/2022
    Signaling through Syk or CARD9 Mediates Species-Specific Anti-Candida Protection in Bone Marrow Chimeric Mice.

    Signaling through Syk or CARD9 Mediates Species-Specific Anti-Candida Protection in Bone Marrow Chimeric Mice.
    Zajta E, Csonka K, Tóth A, Tiszlavicz L, Németh T, Orosz A, Novák Á, Csikós M, Vágvölgyi C, Mócsai A, Gácser A., Free PMC Article

    01/8/2022
    TREM (Triggering Receptor Expressed on Myeloid Cells)-1 Inhibition Attenuates Neuroinflammation via PKC (Protein Kinase C) delta/CARD9 (Caspase Recruitment Domain Family Member 9) Signaling Pathway After Intracerebral Hemorrhage in Mice.

    TREM (Triggering Receptor Expressed on Myeloid Cells)-1 Inhibition Attenuates Neuroinflammation via PKC (Protein Kinase C) δ/CARD9 (Caspase Recruitment Domain Family Member 9) Signaling Pathway After Intracerebral Hemorrhage in Mice.
    Lu Q, Liu R, Sherchan P, Ren R, He W, Fang Y, Huang Y, Shi H, Tang L, Yang S, Zhang JH, Tang J., Free PMC Article

    01/8/2022
    A potential role of caspase recruitment domain family member 9 (Card9) in transverse aortic constriction-induced cardiac dysfunction, fibrosis, and hypertrophy.

    A potential role of caspase recruitment domain family member 9 (Card9) in transverse aortic constriction-induced cardiac dysfunction, fibrosis, and hypertrophy.
    Peterson MR, Getiye Y, Bosch L, Sanders AJ, Smith AR, Haller S, Wilson K, Paul Thomas D, He G.

    10/16/2021
    CARD9 Deficiency Increases Hippocampal Injury Following Acute Neurotropic Picornavirus Infection but Does Not Affect Pathogen Elimination.

    CARD9 Deficiency Increases Hippocampal Injury Following Acute Neurotropic Picornavirus Infection but Does Not Affect Pathogen Elimination.
    Pavasutthipaisit S, Stoff M, Ebbecke T, Ciurkiewicz M, Mayer-Lambertz S, Störk T, Pavelko KD, Lepenies B, Beineke A., Free PMC Article

    07/31/2021
    A critical role for CARD9 in pneumocystis pneumonia host defence.

    A critical role for CARD9 in pneumocystis pneumonia host defence.
    Kottom TJ, Nandakumar V, Hebrink DM, Carmona EM, Limper AH., Free PMC Article

    07/31/2021
    E ff ect of CARD9 Deficiency on Neutrophil-Mediated Host Defense against Pulmonary Infection with Streptococcus pneumoniae.

    Effect of CARD9 Deficiency on Neutrophil-Mediated Host Defense against Pulmonary Infection with Streptococcus pneumoniae.
    Ishizuka S, Yokoyama R, Sato K, Shiroma R, Nakahira A, Yamamoto H, Takano K, Kagesawa T, Miyasaka T, Kasamatsu J, Kanno E, Tanno H, Ishii K, Kawakami K., Free PMC Article

    06/26/2021
    S-Layer From Lactobacillus brevis Modulates Antigen-Presenting Cell Functions via the Mincle-Syk-Card9 Axis.

    S-Layer From Lactobacillus brevis Modulates Antigen-Presenting Cell Functions via the Mincle-Syk-Card9 Axis.
    Prado Acosta M, Goyette-Desjardins G, Scheffel J, Dudeck A, Ruland J, Lepenies B., Free PMC Article

    06/26/2021
    CARD9 promotes autophagy in cardiomyocytes in myocardial ischemia/reperfusion injury via interacting with Rubicon directly.

    CARD9 promotes autophagy in cardiomyocytes in myocardial ischemia/reperfusion injury via interacting with Rubicon directly.
    Li Y, Liang P, Jiang B, Tang Y, Liu X, Liu M, Sun H, Chen C, Hao H, Liu Z, Xiao X.

    06/26/2021
    CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection.

    CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection.
    Campuzano A, Zhang H, Ostroff GR, Dos Santos Dias L, Wüthrich M, Klein BS, Yu JJ, Lara HH, Lopez-Ribot JL, Hung CY., Free PMC Article

    02/13/2021
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