| Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling. | Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling.
Grintsevich EE, Ahmed G, Ginosyan AA, Wu H, Rich SK, Reisler E, Terman JR., Free PMC Article | 10/16/2021 |
| Dm Ime4 depletion affects permeability barrier and Chic function in Drosophila spermatogenesis. | Dm Ime4 depletion affects permeability barrier and Chic function in Drosophila spermatogenesis.
Rockwell AL, Hongay CF. | 09/18/2021 |
| Drosophila Atg9 regulates the actin cytoskeleton via interactions with profilin and Ena. | Drosophila Atg9 regulates the actin cytoskeleton via interactions with profilin and Ena.
Kiss V, Jipa A, Varga K, Takáts S, Maruzs T, Lőrincz P, Simon-Vecsei Z, Szikora S, Földi I, Bajusz C, Tóth D, Vilmos P, Gáspár I, Ronchi P, Mihály J, Juhász G., Free PMC Article | 07/3/2021 |
| Developmental axon regrowth and primary neuron sprouting utilize distinct actin elongation factors. | Developmental axon regrowth and primary neuron sprouting utilize distinct actin elongation factors.
Yaniv SP, Meltzer H, Alyagor I, Schuldiner O., Free PMC Article | 02/20/2021 |
| Insulin/Insulin-like growth factor signaling specifically activates the expression of the actin regulator chickadee, the Drosophila homolog of Profilin, which is essential for promoting the formation of actin extensions and migration through the egg chamber.and migration through the egg chamber. | The Drosophila insulin pathway controls Profilin expression and dynamic actin-rich protrusions during collective cell migration.
Ghiglione C, Jouandin P, Cérézo D, Noselli S. | 09/8/2018 |
| Chic regulates interactions across the somatic permeability barrier around the germline that is essential for Drosophila spermatogenesis. | A somatic permeability barrier around the germline is essential for Drosophila spermatogenesis.
Fairchild MJ, Smendziuk CM, Tanentzapf G. | 03/21/2015 |
| chickadee, the Drosophila gene that encodes profilin, is required cell autonomously to maintain germline stem cells, possibly facilitating localization or maintenance of E-cadherin to the germline stem cell-hub cell interface. | The actin-binding protein profilin is required for germline stem cell maintenance and germ cell enclosure by somatic cyst cells.
Shields AR, Spence AC, Yamashita YM, Davies EL, Fuller MT., Free PMC Article | 03/15/2014 |
| Data show that chic-deficient larvae fail to form a robust actin cable along the wound edge and also fail to form normal filopodial and lamellipodial extensions into the wound gap. | Transcriptional regulation of Profilin during wound closure in Drosophila larvae.
Brock AR, Wang Y, Berger S, Renkawitz-Pohl R, Han VC, Wu Y, Galko MJ., Free PMC Article | 08/31/2013 |
| D. melanogaster DAAM formin represents an extreme class of barbed end regulators gated by profilin. | Characterization of the biochemical properties and biological function of the formin homology domains of Drosophila DAAM.
Barkó S, Bugyi B, Carlier MF, Gombos R, Matusek T, Mihály J, Nyitrai M., Free PMC Article | 05/31/2010 |
| FMRP1 binds the mRNA of the Drosophila profilin and negatively regulates Profilin protein expression | The Drosophila fragile X mental retardation protein controls actin dynamics by directly regulating profilin in the brain.
Reeve SP, Bassetto L, Genova GK, Kleyner Y, Leyssen M, Jackson FR, Hassan BA. | 01/21/2010 |
| D-SCAR and profilin were identified as important regulators of phagocytosis in Drosophila | Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila.
Pearson AM, Baksa K, Rämet M, Protas M, McKee M, Brown D, Ezekowitz RA. | 01/21/2010 |