| FFAR4 activation inhibits lung adenocarcinoma via blocking respiratory chain complex assembly associated mitochondrial metabolism. | FFAR4 activation inhibits lung adenocarcinoma via blocking respiratory chain complex assembly associated mitochondrial metabolism.
Wang Z, Li J, Wang L, Liu Y, Wang W, Chen J, Liang H, Chen YQ, Zhu S., Free PMC Article | 02/1/2024 |
| GPR120/FFAR4: A Potential New Therapeutic Target for Inflammatory Bowel Disease. | GPR120/FFAR4: A Potential New Therapeutic Target for Inflammatory Bowel Disease.
Di Petrillo A, Kumar A, Onali S, Favale A, Fantini MC. | 12/15/2023 |
| Predictive value of first-trimester GPR120 levels in gestational diabetes mellitus. | Predictive value of first-trimester GPR120 levels in gestational diabetes mellitus.
He Q, Lin M, Wu Z, Yu R., Free PMC Article | 10/25/2023 |
| Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells. | Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells.
Karmokar PF, Moniri NH. | 06/25/2023 |
| Immune regulation of poly unsaturated fatty acids and free fatty acid receptor 4. | Immune regulation of poly unsaturated fatty acids and free fatty acid receptor 4.
Duah M, Zhang K, Liang Y, Ayarick VA, Xu K, Pan B. | 01/21/2023 |
| Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells. | Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells.
Karmokar PF, Moniri NH. | 12/10/2022 |
| GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma. | GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma.
Sun X, Chu H, Lei K, Ci Y, Lu H, Wang J, Zhou M, Ren H, Zheng T. | 09/24/2022 |
| Reduced Free Fatty Acid Receptor 4 Gene Expression is Associated With Extreme Obesity and Insulin Resistance in Children. | Reduced Free Fatty Acid Receptor 4 Gene Expression is Associated With Extreme Obesity and Insulin Resistance in Children.
Codoñer-Alejos A, Carrasco-Luna J, Carrasco-García Á, Codoñer-Franch P. | 06/25/2022 |
| Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway. | Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway.
Zhu S, Zhang J, Jiang X, Wang W, Chen YQ., Free PMC Article | 06/25/2022 |
| GPR120 prevents colorectal adenocarcinoma progression by sustaining the mucosal barrier integrity. | GPR120 prevents colorectal adenocarcinoma progression by sustaining the mucosal barrier integrity.
Rubbino F, Garlatti V, Garzarelli V, Massimino L, Spanò S, Iadarola P, Cagnone M, Giera M, Heijink M, Guglielmetti S, Arena V, Malesci A, Laghi L, Danese S, Vetrano S., Free PMC Article | 02/26/2022 |
| GPR120 Ameliorates Apoptosis and Inhibits the Production of Inflammatory Cytokines in Renal Tubular Epithelial Cells. | GPR120 Ameliorates Apoptosis and Inhibits the Production of Inflammatory Cytokines in Renal Tubular Epithelial Cells.
Zhi D, Zhang M, Lin J, Liu P, Duan M. | 11/13/2021 |
| GPR120 promotes radiation resistance in esophageal cancer via regulating AKT and apoptosis pathway. | GPR120 promotes radiation resistance in esophageal cancer via regulating AKT and apoptosis pathway.
Cui Z, Liu J, Sun Q, He Z, Wang C, Zhang X, Ma Q, Li D, Jiang H. | 09/25/2021 |
| Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT. | Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT.
Husted AS, Ekberg JH, Tripp E, Nissen TAD, Meijnikman S, O'Brien SL, Ulven T, Acherman Y, Bruin SC, Nieuwdorp M, Gerhart-Hines Z, Calebiro D, Dragsted LO, Schwartz TW., Free PMC Article | 09/11/2021 |
| Teadenol A in microbial fermented tea acts as a novel ligand on GPR120 to increase GLP-1 secretion. | Teadenol A in microbial fermented tea acts as a novel ligand on GPR120 to increase GLP-1 secretion.
Nagasawa T , Ishimaru K , Higashiyama S , Hama Y , Mitsutake S . | 06/12/2021 |
| The rs11187533 C>T Variant of the FFAR4 Gene Is Associated with Lower Levels of Fasting Glucose and Decreases in Markers of Liver Injury in Children with Obesity. | The rs11187533 C>T Variant of the FFAR4 Gene Is Associated with Lower Levels of Fasting Glucose and Decreases in Markers of Liver Injury in Children with Obesity.
Codoñer-Alejos A, Carrasco-Luna J, Codoñer-Franch P. | 01/9/2021 |
| Long noncoding RNA LINC00662-miR-15b-5p mediated GPR120 dysregulation contributes to osteoarthritis. | Long noncoding RNA LINC00662-miR-15b-5p mediated GPR120 dysregulation contributes to osteoarthritis.
Lu M, Zhou E. | 01/2/2021 |
| Regulation of cell survival through free fatty acid receptor 1 (FFA1) and FFA4 induced by endothelial cells in osteosarcoma cells. | Regulation of cell survival through free fatty acid receptor 1 (FFA1) and FFA4 induced by endothelial cells in osteosarcoma cells.
Minami K, Ueda N, Ishimoto K, Tsujiuchi T. | 12/12/2020 |
| FFAR4 promotes cell proliferation and migration and servers as a potential biomarker for clinicopathological characteristics and prognosis in laryngocarcinoma. | FFAR4 promotes cell proliferation and migration and servers as a potential biomarker for clinicopathological characteristics and prognosis in laryngocarcinoma.
Zhou LZ, Cui YX, Wang WZ, Wu J, Sun Z, Ma SY. | 10/10/2020 |
| Activation of GPR120 promotes the metastasis of breast cancer through the PI3K/Akt/NF-kappaB signaling pathway. | Activation of GPR120 promotes the metastasis of breast cancer through the PI3K/Akt/NF-κB signaling pathway.
Zhang M, Qiu S. | 09/26/2020 |
| free fatty acid receptor 4 is involved in long-term diet-mediated changes to fatty acid taste perception | A low-fat diet up-regulates expression of fatty acid taste receptor gene FFAR4 in fungiform papillae in humans: a co-twin randomised controlled trial.
Costanzo A, Liu D, Nowson C, Duesing K, Archer N, Bowe S, Keast R. | 06/13/2020 |
| Selective FFAR4 activation regulates both islet and enteroendocrine hormone function. | Pharmacological potential of novel agonists for FFAR4 on islet and enteroendocrine cell function and glucose homeostasis.
McCloskey AG, Miskelly MG, Flatt PR, McKillop AM. | 06/6/2020 |
| the mechanisms of docosahexaenoic acid-induced phosphorylation of FFA4-L and subsequent beta-arrestin-2 recruitment and extracellular-signal regulated kinase-1/2 activity, are reported. | Carboxy-Terminal Phosphoregulation of the Long Splice Isoform of Free-Fatty Acid Receptor-4 Mediates β-Arrestin Recruitment and Signaling to ERK1/2.
Senatorov IS, Cheshmehkani A, Burns RN, Singh K, Moniri NH., Free PMC Article | 04/25/2020 |
| Metabolic and physiological role of FFAR1 (GPR40), FFAR4 (GPR120), FFAR3 (GPR41) and FFAR2 (GPR43) is REVIEWED. | Free Fatty Acid Receptors in Health and Disease.
Kimura I, Ichimura A, Ohue-Kitano R, Igarashi M. | 04/25/2020 |
| GPR120/FFAR4-mediating system could be a key signaling pathway to prevent the development of NASH. | [Involvement of the Free Fatty Acid Receptor GPR120/FFAR4 in the Development of Nonalcoholic Steatohepatitis].
Nakamoto K, Tokuyama S. | 02/8/2020 |
| Generally positive correlations are found between the total amount of lipids and expression levels of GPR120 and FGF21 in gestational diabetes mellitus patients. FGF21 expression is induced by GPR120 activation in THP-1cells and white blood cells. | Increased GPR120 level is associated with gestational diabetes mellitus.
He Q, Zhu S, Lin M, Yang Q, Wei L, Zhang J, Jiang X, Zhu D, Lu X, Chen YQ. | 02/8/2020 |