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    IFNB1 interferon beta 1 [ Homo sapiens (human) ]

    Gene ID: 3456, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    FHL2 Inhibits SARS-CoV-2 Replication by Enhancing IFN-beta Expression through Regulating IRF-3.

    FHL2 Inhibits SARS-CoV-2 Replication by Enhancing IFN-β Expression through Regulating IRF-3.
    Xu Z, Tian M, Tan Q, Hao P, Gao Z, Li C, Jin N., Free PMC Article

    01/16/2024
    C5aR2 Regulates STING-Mediated Interferon Beta Production in Human Macrophages.

    C5aR2 Regulates STING-Mediated Interferon Beta Production in Human Macrophages.
    Wright O, Harris A, Nguyen VD, Zhou Y, Durand M, Jayyaratnam A, Gormley D, O'Neill LAJ, Triantafilou K, Nichols EM, Booty LM., Free PMC Article

    01/12/2024
    Human lung vascular endothelium may limit infection with HRV16 via IFN-beta-dependent mechanisms.

    Human lung vascular endothelium may limit infection with HRV16 via IFN-β-dependent mechanisms.
    Gawrysiak M, Szewczyk R, Kobierecki M, Szymański M, Gajewski A, Gulbas I, Michlewska S, Chałubiński M.

    01/11/2024
    Coxsackievirus A6 2C protein antagonizes IFN-beta production through MDA5 and RIG-I depletion.

    Coxsackievirus A6 2C protein antagonizes IFN-β production through MDA5 and RIG-I depletion.
    Wang S-H, Du J, Yu J, Zhao Y, Wang Y, Hua S, Zhao K., Free PMC Article

    12/6/2023
    Hypoxia and acidity regulate immune checkpoint molecule and IFN-beta expression in non-small cell lung cancer cell lines.

    Hypoxia and acidity regulate immune checkpoint molecule and IFN-β expression in non-small cell lung cancer cell lines.
    Mitrakas AG, Giatromanolaki A, Koukourakis MI.

    06/26/2023
    Pellino3 ligase negatively regulates influenza B dependent RIG-I signalling through downregulation of TRAF3-mediated induction of the transcription factor IRF3 and IFNbeta production.

    Pellino3 ligase negatively regulates influenza B dependent RIG-I signalling through downregulation of TRAF3-mediated induction of the transcription factor IRF3 and IFNβ production.
    Kula A, Makuch E, Lisowska M, Reniewicz P, Lipiński T, Siednienko J.

    06/16/2023
    Endoplasmic reticulum stress response and the regulation of endometrial interferon-beta production.

    Endoplasmic reticulum stress response and the regulation of endometrial interferon-beta production.
    Sethuram R, Bukowski M, Hernandez F, You Y, Puscheck E, Mor G, Jeyasuria P, Condon JC.

    05/23/2023
    IFN-beta activates cytotoxic function of human natural killer cells toward IL-27 and poly(I:C) stimulated PC3 and DU145 cells.

    IFN-β activates cytotoxic function of human natural killer cells toward IL-27 and poly(I:C) stimulated PC3 and DU145 cells.
    Kourko O, Hawke LG, Ormiston ML, Gee K.

    05/8/2023
    Early plasma interferon-beta levels as a predictive marker of COVID-19 severe clinical events in adult patients.

    Early plasma interferon-β levels as a predictive marker of COVID-19 severe clinical events in adult patients.
    Berri F, N'Guyen Y, Callon D, Lebreil AL, Glenet M, Heng L, Pham BN, Bani-Sadr F, Andreoletti L, Reims COVID-19 Study Group., Free PMC Article

    02/4/2023
    Synergism of TNF-alpha and IFN-beta triggers human airway epithelial cells death by apoptosis and pyroptosis.

    Synergism of TNF-α and IFN-β triggers human airway epithelial cells death by apoptosis and pyroptosis.
    Sun R, Jiang K, Zeng C, Zhu R, Chu H, Liu H, Du J., Free PMC Article

    01/28/2023
    The double-stranded RNA-dependent protein kinase PKR negatively regulates the protein expression of IFN-beta induced by RIG-I signaling.

    The double-stranded RNA-dependent protein kinase PKR negatively regulates the protein expression of IFN-β induced by RIG-I signaling.
    Matsumiya T, Shiba Y, Ding J, Kawaguchi S, Seya K, Imaizumi T.

    01/21/2023
    IFN-beta1b induces OAS3 to inhibit EV71 via IFN-beta1b/JAK/STAT1 pathway.

    IFN-β1b induces OAS3 to inhibit EV71 via IFN-β1b/JAK/STAT1 pathway.
    Zheng B, Zhou X, Tian L, Wang J, Zhang W., Free PMC Article

    10/22/2022
    Endogenous IFNbeta expression predicts outcome in critical patients with COVID-19.

    Endogenous IFNβ expression predicts outcome in critical patients with COVID-19.
    Menezes SM, Braz M, Llorens-Rico V, Wauters J, Van Weyenbergh J., Free PMC Article

    05/7/2022
    Rasmussen's encephalitis is characterized by relatively lower production of IFN-beta and activated cytotoxic T cell upon herpes viruses infection.

    Rasmussen's encephalitis is characterized by relatively lower production of IFN-β and activated cytotoxic T cell upon herpes viruses infection.
    Wang YS, Liu D, Wang X, Luo QL, Ding L, Fan DY, Cai QL, Tang CY, Yang W, Guan YG, Li TF, Wang PG, Luan GM, An J., Free PMC Article

    04/16/2022
    Cells Stimulated with More Than One Toll-Like Receptor-Ligand in the Presence of a MyD88 Inhibitor Augmented Interferon-beta via MyD88-Independent Signaling Pathway.

    Cells Stimulated with More Than One Toll-Like Receptor-Ligand in the Presence of a MyD88 Inhibitor Augmented Interferon-β via MyD88-Independent Signaling Pathway.
    Saikh KU, Ranji CM.

    03/12/2022
    Human IFIT3 Protein Induces Interferon Signaling and Inhibits Adenovirus Immediate Early Gene Expression.

    Human IFIT3 Protein Induces Interferon Signaling and Inhibits Adenovirus Immediate Early Gene Expression.
    Chikhalya A, Dittmann M, Zheng Y, Sohn SY, Rice CM, Hearing P., Free PMC Article

    03/12/2022
    STING-Mediated Interferon Induction by Herpes Simplex Virus 1 Requires the Protein Tyrosine Kinase Syk.

    STING-Mediated Interferon Induction by Herpes Simplex Virus 1 Requires the Protein Tyrosine Kinase Syk.
    Wang C, Sharma N, Veleeparambil M, Kessler PM, Willard B, Sen GC., Free PMC Article

    02/26/2022
    Human Cytomegalovirus UL138 Protein Inhibits the STING Pathway and Reduces Interferon Beta mRNA Accumulation during Lytic and Latent Infections.

    Human Cytomegalovirus UL138 Protein Inhibits the STING Pathway and Reduces Interferon Beta mRNA Accumulation during Lytic and Latent Infections.
    Albright ER, Mickelson CK, Kalejta RF., Free PMC Article

    02/26/2022
    Herpes Simplex Virus Type 1 Infection Disturbs the Mitochondrial Network, Leading to Type I Interferon Production through the RNA Polymerase III/RIG-I Pathway.

    Herpes Simplex Virus Type 1 Infection Disturbs the Mitochondrial Network, Leading to Type I Interferon Production through the RNA Polymerase III/RIG-I Pathway.
    Berry N, Suspène R, Caval V, Khalfi P, Beauclair G, Rigaud S, Blanc H, Vignuzzi M, Wain-Hobson S, Vartanian JP., Free PMC Article

    02/26/2022
    Escherichia coli infection activates the production of IFN-alpha and IFN-beta via the JAK1/STAT1/2 signaling pathway in lung cells.

    Escherichia coli infection activates the production of IFN-α and IFN-β via the JAK1/STAT1/2 signaling pathway in lung cells.
    Jin Y, Jia Z, Cai Q, Sun Y, Liu Z., Free PMC Article

    02/5/2022
    Targeting Aryl Hydrocarbon Receptor Signaling Enhances Type I Interferon-Independent Resistance to Herpes Simplex Virus.

    Targeting Aryl Hydrocarbon Receptor Signaling Enhances Type I Interferon-Independent Resistance to Herpes Simplex Virus.
    Chen J, Liang J, Xu H, Liu W, Liu S, Duan L, Li F, Wang Z, Liu Y, McSharry B, Feng CG, Zhang G., Free PMC Article

    01/29/2022
    Differences in IFNbeta secretion upon Rab1 inactivation in cells exposed to distinct innate immune stimuli.

    Differences in IFNβ secretion upon Rab1 inactivation in cells exposed to distinct innate immune stimuli.
    Yang J, Zhou X, Zhang R, Sun H, You F, Jiang Z., Free PMC Article

    01/29/2022
    Genes for tRNA recycling are upregulated in response to infection with Theiler's mouse encephalitis virus.

    Genes for tRNA recycling are upregulated in response to infection with Theiler's mouse encephalitis virus.
    Seki M, Komuro A, Ishikawa T, Takahashi M, Nashimoto M.

    01/15/2022
    Cellular 5'-3' mRNA Exoribonuclease XRN1 Inhibits Interferon Beta Activation and Facilitates Influenza A Virus Replication.

    Cellular 5'-3' mRNA Exoribonuclease XRN1 Inhibits Interferon Beta Activation and Facilitates Influenza A Virus Replication.
    Liu YC, Mok BW, Wang P, Kuo RL, Chen H, Shih SR., Free PMC Article

    12/25/2021
    Methylation of viral mRNA cap structures by PCIF1 attenuates the antiviral activity of interferon-beta.

    Methylation of viral mRNA cap structures by PCIF1 attenuates the antiviral activity of interferon-β.
    Tartell MA, Boulias K, Hoffmann GB, Bloyet LM, Greer EL, Whelan SPJ., Free PMC Article

    12/18/2021
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