| These results provide supportive evidence that sNPF-producing neurons promote long-lasting increases in sleep, and show for the first time that even brief periods of activation of these neurons can cause changes in behavior that persist after cessation of activation. | Optogenetic activation of short neuropeptide F (sNPF) neurons induces sleep in Drosophila melanogaster.
Juneau ZC, Stonemetz JM, Toma RF, Possidente DR, Heins RC, Vecsey CG., Free PMC Article | 07/4/2020 |
| Light and the neuropeptides PDF and sNPF act dynamically at distinct hubs of the circadian neural circuit to produce multiple suppressive events that create the proper tempo and sequence of circadian pacemaker neuronal activities. | A Series of Suppressive Signals within the Drosophila Circadian Neural Circuit Generates Sequential Daily Outputs.
Liang X, Holy TE, Taghert PH., Free PMC Article | 08/5/2017 |
| Findings indicate that short neuropeptide F (sNPF) and corazonin (CRZ) co-released from a small set of neurons regulate insulin-producing cells (IPCs) stress resistance and metabolism. | Identified peptidergic neurons in the Drosophila brain regulate insulin-producing cells, stress responses and metabolism by coexpressed short neuropeptide F and corazonin.
Kapan N, Lushchak OV, Luo J, Nässel DR., Free PMC Article | 11/21/2015 |
| Loss of function of sNPF and sNPFR1 also elevated sleep. | Regulation of sleep by the short neuropeptide F (sNPF) in Drosophila melanogaster.
Chen W, Shi W, Li L, Zheng Z, Li T, Bai W, Zhao Z. | 03/1/2014 |
| Here we show that a neuropeptide precursor gene encoding four types of short neuropeptide F (sNPF) is required in the Kenyon cells for appetitive olfactory memory. | Short neuropeptide F acts as a functional neuromodulator for olfactory memory in Kenyon cells of Drosophila mushroom bodies.
Knapek S, Kahsai L, Winther AM, Tanimoto H, Nässel DR., Free PMC Article | 06/1/2013 |
| Different layers of the fan-shaped body sNPFR1 | Distribution of metabotropic receptors of serotonin, dopamine, GABA, glutamate, and short neuropeptide F in the central complex of Drosophila.
Kahsai L, Carlsson MA, Winther AM, Nässel DR. | 07/21/2012 |
| We have demonstrated here that subsets of Drosophila lateral clock neurons are heterogeneous with respect to expression of neuroactive compounds, including ion transport peptide and short neuropeptide F | Peptidergic clock neurons in Drosophila: ion transport peptide and short neuropeptide F in subsets of dorsal and ventral lateral neurons.
Johard HA, Yoishii T, Dircksen H, Cusumano P, Rouyer F, Helfrich-Förster C, Nässel DR. | 01/21/2010 |
| These results indicate that sNPF1 and sNPF2 peptides processed from the sNPF precursor are sufficient for regulating body growth through the ERK-insulin pathway in Drosophila. | Processed short neuropeptide F peptides regulate growth through the ERK-insulin pathway in Drosophila melanogaster.
Lee KS, Hong SH, Kim AK, Ju SK, Kwon OY, Yu K. | 01/21/2010 |
| Data show Drosophila brain expressing short neuropeptide F transcript and short neuropeptide F peptide. Most of these | A large population of diverse neurons in the Drosophila central nervous system expresses short neuropeptide F, suggesting multiple distributed peptide functions.
Nässel DR, Enell LE, Santos JG, Wegener C, Johard HA., Free PMC Article | 01/21/2010 |
| Results show that Drosophila short neuropeptide F, an orthologue of mammalian neuropeptide Y, and sNPF receptor sNPFR1 regulate expression of insulin-like peptides. | Drosophila short neuropeptide F signalling regulates growth by ERK-mediated insulin signalling.
Lee KS, Kwon OY, Lee JH, Kwon K, Min KJ, Jung SA, Kim AK, You KH, Tatar M, Yu K. | 01/21/2010 |
| sNPF is expressed in the nervous systems to control food intake and regulate body size in Drosophila melanogaster | Drosophila short neuropeptide F regulates food intake and body size.
Lee KS, You KH, Choo JK, Han YM, Yu K. | 01/21/2010 |