| Validation and classification of RNA binding proteins identified by mRNA interactome capture. | Validation and classification of RNA binding proteins identified by mRNA interactome capture.
Vaishali, Dimitrova-Paternoga L, Haubrich K, Sun M, Ephrussi A, Hennig J., Free PMC Article | 10/2/2021 |
| NOD produces congression forces by microtubule plus end-directed motility and tip-tracking on polymerizing microtubule plus ends via association with EB1. | NOD is a plus end-directed motor that binds EB1 via a new microtubule tip localization sequence.
Ye AA, Verma V, Maresca TJ., Free PMC Article | 09/21/2019 |
| The authors that the cytokine receptor homolog Dome, acting downstream of the niche-derived ligand Upd, directly binds to the microtubule-binding protein Eb1 to regulate spindle orientation in Drosophila male germline stem cells (GSCs). | Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division.
Chen C, Cummings R, Mordovanakis A, Hunt AJ, Mayer M, Sept D, Yamashita YM., Free PMC Article | 06/8/2019 |
| tip-tracking of kinesin-14 occurs through several concurrent mechanisms: binding of kinesin only to EB1 located at the MT end, interaction of the kinesin molecules with a composite site formed by EB1 and the MT tip, and probably surface diffusion of the tail along MT. | Insights into the process of EB1-dependent tip-tracking of kinesin-14 Ncd. The role of the microtubule.
Szczęsna E, Kasprzak AA. | 02/18/2017 |
| Drosophila melanogaster larval muscles, exhibiting both elastic features contributed by the stretching capacity of MSP300 (nesprin) and rigidity provided by a perinuclear network of microtubules stabilized by Shot (spectraplakin) and EB1. | Nesprin provides elastic properties to muscle nuclei by cooperating with spectraplakin and EB1.
Wang S, Reuveny A, Volk T., Free PMC Article | 08/1/2015 |
| Kank as an EB1 interactor that predominantly localises to embryonic attachment sites between muscle and tendon cells | Kank Is an EB1 interacting protein that localises to muscle-tendon attachment sites in Drosophila.
Clohisey SM, Dzhindzhev NS, Ohkura H., Free PMC Article | 05/23/2015 |
| Aptamers binding to human EB1 and EB3, which have sequence requirements similar to but distinct from each other and from Drosophila EB1, were identified. | Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics.
Leśniewska K, Warbrick E, Ohkura H., Free PMC Article | 11/29/2014 |
| In Drosophila melanogaster S2 cells, Dynamic microtubules (MT) tip-localizing protein EB1, has been identified as being critical for accelerating MT growth and promoting catastrophe events, thus resulting in the formation of dynamic MTs. | Reconstitution of dynamic microtubules with Drosophila XMAP215, EB1, and Sentin.
Li W, Moriwaki T, Tani T, Watanabe T, Kaibuchi K, Goshima G., Free PMC Article | 02/23/2013 |
| Binding of shot protein to EB1 requires SxIP motifs in Shot's carboxy-terminal tail (Ctail). Mutations of these motifs abolish Shot functions in axonal growth. | Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins).
Alves-Silva J, Sánchez-Soriano N, Beaven R, Klein M, Parkin J, Millard TH, Bellen HJ, Venken KJ, Ballestrem C, Kammerer RA, Prokop A., Free PMC Article | 09/22/2012 |
| Data show that kinesin-2, and the +TIPS EB1 and APC, are required for uniform dendrite microtubule polarity. | Directed microtubule growth, +TIPs, and kinesin-2 are required for uniform microtubule polarity in dendrites.
Mattie FJ, Stackpole MM, Stone MC, Clippard JR, Rudnick DA, Qiu Y, Tao J, Allender DL, Parmar M, Rolls MM., Free PMC Article | 04/9/2011 |
| Eb1 is essential during development and plays a crucial role in the integrity of chordotonal mechanosensory organs. | EB1 is essential during Drosophila development and plays a crucial role in the integrity of chordotonal mechanosensory organs.
Elliott SL, Cullen CF, Wrobel N, Kernan MJ, Ohkura H., Free PMC Article | 01/21/2010 |
| Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle. | Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle.
Rogers SL, Rogers GC, Sharp DJ, Vale RD., Free PMC Article | 01/21/2010 |