| Disruption of the SP-A/SP-R210L (MYO18Aalpha) pathway prolongs gestation and reduces fetal survival during lipopolysaccharide-induced parturition in late gestation. | Disruption of the SP-A/SP-R210(L) (MYO18Aα) pathway prolongs gestation and reduces fetal survival during lipopolysaccharide-induced parturition in late gestation.
Guan Z, Worth B, Umstead TM, Amatya S, Booth J, Chroneos ZC., | 04/11/2024 |
| Tanc1/2 TPR domain interacts with Myo18a C-terminus and undergoes liquid-liquid phase separation. | Tanc1/2 TPR domain interacts with Myo18a C-terminus and undergoes liquid-liquid phase separation.
Yang Q, Liu H, Zhong D, Li Z, Li J, Xiao K, Liu W. | 01/17/2024 |
| Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages. | Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages.
Yau E, Chen Y, Song C, Webb J, Carillo M, Kawasawa YI, Tang Z, Takahashi Y, Umstead TM, Dovat S, Chroneos ZC., Free PMC Article | 03/19/2022 |
| Cutting Edge: Myosin 18A Is a Novel Checkpoint Regulator in B Cell Differentiation and Antibody-Mediated Immunity. | Cutting Edge: Myosin 18A Is a Novel Checkpoint Regulator in B Cell Differentiation and Antibody-Mediated Immunity.
Cheung MB, Enyindah-Asonye G, Matsui K, Kosik I, Dvorina N, Baldwin WM 3rd, Yewdell JW, Gupta N., Free PMC Article | 10/2/2021 |
| Myosin 18Aalpha targets the guanine nucleotide exchange factor beta-Pix to the dendritic spines of cerebellar Purkinje neurons and promotes spine maturation. | Myosin 18Aα targets the guanine nucleotide exchange factor β-Pix to the dendritic spines of cerebellar Purkinje neurons and promotes spine maturation.
Alexander CJ, Barzik M, Fujiwara I, Remmert K, Wang YX, Petralia RS, Friedman TB, Hammer JA., Free PMC Article | 06/19/2021 |
| we have identified a previously unrecognized sarcomere component, a large novel isoform (denoted Myo18Agamma) of Myo18A. Thus, both members of class XVIII myosins are critical components of cardiac sarcomeres | A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart.
Horsthemke M, Nutter LMJ, Bachg AC, Skryabin BV, Honnert U, Zobel T, Bogdan S, Stoll M, Seidl MD, Müller FU, Ravens U, Unger A, Linke WA, van Gorp PRR, de Vries AAF, Bähler M, Hanley PJ., Free PMC Article | 01/11/2020 |
| MYO18A has the potential to form a multiprotein complex that links the Golgi apparatus to F-actin, which regulates muscle integrity and function during early development | Identification of novel MYO18A interaction partners required for myoblast adhesion and muscle integrity.
Cao JM, Cheng XN, Li SQ, Heller S, Xu ZG, Shi DL., Free PMC Article | 05/19/2018 |
| studies revealed a novel physical association between SP-R210S, CD14, and SR-A leading to an enhanced response to LPS, and found that SP-R210L and SP-R210S regulate internalization of CD14 via distinct macropinocytosis-like mechanisms | SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation.
Yang L, Carrillo M, Wu YM, DiAngelo SL, Silveyra P, Umstead TM, Halstead ES, Davies ML, Hu S, Floros J, McCormack FX, Christensen ND, Chroneos ZC., Free PMC Article | 02/6/2016 |
| Data showed that M18A coassembles with NM2 into mixed bipolar filaments. | Myosin 18A coassembles with nonmuscle myosin 2 to form mixed bipolar filaments.
Billington N, Beach JR, Heissler SM, Remmert K, Guzik-Lendrum S, Nagy A, Takagi Y, Shao L, Li D, Yang Y, Zhang Y, Barzik M, Betzig E, Hammer JA 3rd, Sellers JR., Free PMC Article | 01/16/2016 |
| Mammalian myosin-18A is a highly divergent myosin that does not operate as a traditional molecular motor in cells | Mammalian myosin-18A, a highly divergent myosin.
Guzik-Lendrum S, Heissler SM, Billington N, Takagi Y, Yang Y, Knight PJ, Homsher E, Sellers JR., Free PMC Article | 06/1/2013 |
| p110 myosin XVIIIA lacks a PDZ domain and, in addition, it may lack motor activity. The phosphorylation of p110 myosin XVIIIA by CSF-1 may alter its cellular localization or target its association with other proteins. | A novel 110 kDa form of myosin XVIIIA (MysPDZ) is tyrosine-phosphorylated after colony-stimulating factor-1 receptor signalling.
Cross M, Csar XF, Wilson NJ, Manes G, Addona TA, Marks DC, Whitty GA, Ashman K, Hamilton JA., Free PMC Article | 01/21/2010 |
| MyoXVIIIA constitutes a novel receptor for SP-A | Identification of the surfactant protein A receptor 210 as the unconventional myosin 18A.
Yang CH, Szeliga J, Jordan J, Faske S, Sever-Chroneos Z, Dorsett B, Christian RE, Settlage RE, Shabanowitz J, Hunt DF, Whitsett JA, Chroneos ZC., Free PMC Article | 01/21/2010 |