| The effect of experimental infection with P. aeruginosa on trpl expression in male Drosophila melanogaster flies from different genetic backgrounds exposed by pricking or by ingestion showed downregulation in the whole body and the intestines. The downregulation of trpl in gammaCop mutant males is not confirmed by qRT-PCR data. | Effects of Pseudomonas aeruginosa infection on the expression profile of transient receptor potential-like (TRPL) gene from Drosophila melanogaster.
Mihalache (Radu) MR, Raþiu AC, Neagu A, Lazãr V, Chifiriuc MC, Ecovoiu AA. | 05/19/2018 |
| effects of cholesterol depletion on the TRPL channel activity | Depletion of Membrane Cholesterol Suppresses Drosophila Transient Receptor Potential-Like (TRPL) Channel Activity.
Peters M, Katz B, Lev S, Zaguri R, Gutorov R, Minke B. | 04/28/2018 |
| CG17352 (CULD) plays an important role in the endocytic turnover of Rh1 and TRPL. | CULD is required for rhodopsin and TRPL channel endocytic trafficking and survival of photoreceptor cells.
Xu Y, Wang T., Free PMC Article | 12/17/2016 |
| conclusion, TTD14 is a novel regulator of TRPL trafficking, involved in internalization and subsequent sorting of TRPL into the recycling pathway that enables this ion channel to return to the plasma membrane | The GTP- and Phospholipid-Binding Protein TTD14 Regulates Trafficking of the TRPL Ion Channel in Drosophila Photoreceptor Cells.
Cerny AC, Altendorfer A, Schopf K, Baltner K, Maag N, Sehn E, Wolfrum U, Huber A., Free PMC Article | 06/4/2016 |
| The transient receptor potential-like (TRPL) cation channel is a direct target for camphor in gustatory receptor neurons; long-term feeding on a camphor diet leads to reversible downregulation of TRPL protein concentrations. | Food experience-induced taste desensitization modulated by the Drosophila TRPL channel.
Zhang YV, Raghuwanshi RP, Shen WL, Montell C., Free PMC Article | 11/30/2013 |
| TRP and TRPL assemble exclusively as homomultimeric channels in their native environment. | Drosophila TRP and TRPL are assembled as homomultimeric channels in vivo.
Katz B, Oberacker T, Richter D, Tzadok H, Peters M, Minke B, Huber A., Free PMC Article | 11/30/2013 |
| a light-dependent switch in the phosphorylation pattern of the TRPL channel mediates stable expression of TRPL in the rhabdomeres upon prolonged dark-adaptation. | Mutation of light-dependent phosphorylation sites of the Drosophila transient receptor potential-like (TRPL) ion channel affects its subcellular localization and stability.
Cerny AC, Oberacker T, Pfannstiel J, Weigold S, Will C, Huber A., Free PMC Article | 08/10/2013 |
| These observations show that reduction in TRPC channel function significantly reduces the sensitivity of the olfactory response to CO(2) concentrations of 5% or less in adult Drosophila | Mutants in Drosophila TRPC channels reduce olfactory sensitivity to carbon dioxide.
Badsha F, Kain P, Prabhakar S, Sundaram S, Padinjat R, Rodrigues V, Hasan G., Free PMC Article | 06/1/2013 |
| Vesicle exocytosis depends on cacophony, TRP and TRPL. | TRP, TRPL and cacophony channels mediate Ca2+ influx and exocytosis in photoreceptors axons in Drosophila.
Astorga G, Härtel S, Sanhueza M, Bacigalupo J., Free PMC Article | 02/9/2013 |
| TRPL channel is constitutively active in S2 cells but is silent in HEK cells. | The activity of the TRP-like channel depends on its expression system.
Lev S, Katz B, Minke B., Free PMC Article | 10/20/2012 |
| The involvement of de novo protein synthesis in TRPL translocation, was examined. | Mechanisms underlying stage-1 TRPL channel translocation in Drosophila photoreceptors.
Lieu MH, Vallejos MJ, Michael E, Tsunoda S., Free PMC Article | 06/30/2012 |
| PI(4,5)P(2) is a crucial substrate for PLC-mediated activation of the trpl channels, whereas PUFA may function as the channel activator. | Signal-dependent hydrolysis of phosphatidylinositol 4,5-bisphosphate without activation of phospholipase C: implications on gating of Drosophila TRPL (transient receptor potential-like) channel.
Lev S, Katz B, Tzarfaty V, Minke B., Free PMC Article | 03/3/2012 |
| found that rab proteins, Rab5 and RabX4, are required for the internalization of TRPL into the cell body | The Drosophila TRPL ion channel shares a Rab-dependent translocation pathway with rhodopsin.
Oberegelsbacher C, Schneidler C, Voolstra O, Cerny A, Huber A. | 11/26/2011 |
| the essential function of the TRP channels in TRPL translocation is to enhance Ca(2+)-influx. | Translocation of the Drosophila transient receptor potential-like (TRPL) channel requires both the N- and C-terminal regions together with sustained Ca2+ entry.
Richter D, Katz B, Oberacker T, Tzarfaty V, Belusic G, Minke B, Huber A., Free PMC Article | 11/26/2011 |
| the unitary currents from Drosophila trpl and trp photoreceptors correspond to TRP and TRPL. | Unitary recordings of TRP and TRPL channels from isolated Drosophila retinal photoreceptor rhabdomeres: activation by light and lipids.
Delgado R, Bacigalupo J. | 01/21/2010 |
| TRPL and TRP are required for cool avoidance; however they are dispensable for warm avoidance | Distinct TRP channels are required for warm and cool avoidance in Drosophila melanogaster.
Rosenzweig M, Kang K, Garrity PA., Free PMC Article | 01/21/2010 |
| TRPL translocation represents a novel mechanism to fine tune visual responses. | Light-regulated subcellular translocation of Drosophila TRPL channels induces long-term adaptation and modifies the light-induced current.
Bähner M, Frechter S, Da Silva N, Minke B, Paulsen R, Huber A. | 01/21/2010 |
| Arrestin2 is required for the rhabdomeric localization and stability of TRPL channels. | Two stages of light-dependent TRPL-channel translocation in Drosophila photoreceptors.
Cronin MA, Lieu MH, Tsunoda S. | 01/21/2010 |
| Whole cell recordings from a Drosophila mutant expressing only TRPL indicated that Ca(2+) block also accounts for the voltage dependence of the native TRPL channels. | Open channel block by Ca2+ underlies the voltage dependence of drosophila TRPL channel.
Parnas M, Katz B, Minke B., Free PMC Article | 01/21/2010 |