| POSTN promotes nucleus pulposus cell senescence and extracellular matrix metabolism via activing Wnt/beta-catenin and NF-kappaB signal pathway in intervertebral disc degeneration. | POSTN promotes nucleus pulposus cell senescence and extracellular matrix metabolism via activing Wnt/β-catenin and NF-κB signal pathway in intervertebral disc degeneration.
Zhu D, Chen S, Sheng P, Wang Z, Li Y, Kang X. | 08/30/2024 |
| Self-amplifying loop of NF-kappaB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration. | Self-amplifying loop of NF-κB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration.
Wu J, Chen Y, Liao Z, Liu H, Zhang S, Zhong D, Qiu X, Chen T, Su D, Ke X, Wan Y, Zhou T, Su P., Free PMC Article | 10/15/2022 |
| Periostin aggravates the early phase of traumatic brain injury via the MAPK/ERK pathway. | Periostin aggravates the early phase of traumatic brain injury via the MAPK/ERK pathway.
Zheng Y, Zeng L, Dong X, Du Q, Gao Y. | 06/18/2022 |
| POSTN promotes diabetic vascular calcification by interfering with autophagic flux. | POSTN promotes diabetic vascular calcification by interfering with autophagic flux.
Sun XJ, Ma WQ, Zhu Y, Liu NF. | 01/22/2022 |
| Periostin promotes arterial calcification through PPARgamma-related glucose metabolism reprogramming. | Periostin promotes arterial calcification through PPARγ-related glucose metabolism reprogramming.
Zhu Y, Ji JJ, Wang XD, Sun XJ, Li M, Wei Q, Ren LQ, Liu NF. | 07/24/2021 |
| Periostin aggravates NLRP3 inflammasome-mediated pyroptosis in myocardial ischemia-reperfusion injury. | Periostin aggravates NLRP3 inflammasome-mediated pyroptosis in myocardial ischemia-reperfusion injury.
Yao L, Song J, Meng XW, Ge JY, Du BX, Yu J, Ji FH. | 07/17/2021 |
| Functional regeneration and repair of tendons using biomimetic scaffolds loaded with recombinant periostin. | Functional regeneration and repair of tendons using biomimetic scaffolds loaded with recombinant periostin.
Wang Y, Jin S, Luo D, He D, Shi C, Zhu L, Guan B, Li Z, Zhang T, Zhou Y, Wang CY, Liu Y., Free PMC Article | 03/20/2021 |
| Periostin Mediates Oestrogen-Induced Osteogenic Differentiation of Bone Marrow Stromal Cells in Ovariectomised Rats. | Periostin Mediates Oestrogen-Induced Osteogenic Differentiation of Bone Marrow Stromal Cells in Ovariectomised Rats.
Li C, Li X, Wang X, Miao P, Liu J, Li C, Li D, Zhou W, Jin Z, Cao M., Free PMC Article | 02/13/2021 |
| Periostin functions as a profibrotic and proinflammatory factor in nephron loss-associated chronic kidney disease. Periostin possibly triggers renal inflammation by restraining basal autophagic flux. | Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D. | 06/20/2020 |
| Data show that the levels of periostin (Postn) in ovariectomy (OVX)-bone marrow mesenchymal stem cells (BMMSCs) were significantly reduced. | Periostin-modified bone marrow mesenchymal stem cells from osteoporotic rats promote alveolar bone regeneration.
Li D, Zhou W, Cao M. | 04/25/2020 |
| High POSTN expression is associated with renal and cardiac dysfunction. | Periostin contributes to renal and cardiac dysfunction in rats with chronic kidney disease: Reduction of PPARα.
Bian X, Su X, Wang Y, Zhao G, Zhang B, Li D. | 07/13/2019 |
| Increased expression of Periostin promotes liver fibrogenesis by activating lysyl oxidase. | Periostin promotes liver fibrogenesis by activating lysyl oxidase in hepatic stellate cells.
Kumar P, Smith T, Raeman R, Chopyk DM, Brink H, Liu Y, Sulchek T, Anania FA., Free PMC Article | 02/16/2019 |
| In vitro analysis using LX2 HSC cells indicated that ATII can augment TGFbeta1 and collagen type I alpha1 mRNA expression via periostin expression, suggesting that the interaction between ATII and periostin may serve a role in liver fibrosis development. In conclusion, blockade of ATIIinduced periostin may suppress the progression of liver fibrosis development. | Periostin cross‑reacts with the renin‑angiotensin system during liver fibrosis development.
Takeda K, Noguchi R, Kitade M, Namisaki T, Moriya K, Kawaratani H, Okura Y, Kaji K, Aihara Y, Douhara A, Nishimura N, Sawada Y, Seki K, Yoshiji H., Free PMC Article | 07/28/2018 |
| the results of the current study suggested that oxidative stressinduced periostin is involved in myocardial fibrosis and hypertension. The present study demonstrated that periostin inhibition may be a promising approach for the inhibition of hypertension-induced cardiac remodeling. | Periostin expression induced by oxidative stress contributes to myocardial fibrosis in a rat model of high salt-induced hypertension.
Wu H, Chen L, Xie J, Li R, Li GN, Chen QH, Zhang XL, Kang LN, Xu B., Free PMC Article | 04/8/2017 |
| therapeutics that specifically inhibit Pn exon-17, via a neutralizing antibody or drug, without suppressing other periostin variants might offer a new class of medication for the treatment of acute myocardial infarction patients. | Selective Blockade of Periostin Exon 17 Preserves Cardiac Performance in Acute Myocardial Infarction.
Taniyama Y, Katsuragi N, Sanada F, Azuma J, Iekushi K, Koibuchi N, Okayama K, Ikeda-Iwabu Y, Muratsu J, Otsu R, Rakugi H, Morishita R. | 05/21/2016 |
| In conclusion, naringin could prevent progress of disuse osteoporosis in rats, which may be mediated by increased periostin expression and subsequently inhibition of sclerostin and activation of Wnt/beta-catenin signaling pathways. | Involvement of periostin-sclerostin-Wnt/β-catenin signaling pathway in the prevention of neurectomy-induced bone loss by naringin.
Lv J, Sun X, Ma J, Ma X, Xing G, Wang Y, Sun L, Wang J, Li F, Li Y. | 04/23/2016 |
| Periostin plays a crucial role in cardiac remodeling in diabetic cardiomyopathy. | Elevated expression of periostin in diabetic cardiomyopathy and the effect of valsartan.
Guan J, Liu WQ, Xing MQ, Shi Y, Tan XY, Jiang CQ, Dai HY., Free PMC Article | 04/9/2016 |
| POSTN significantly enhances neural stem cell proliferation and differentiation after hypoxia-ischemia. | Periostin Promotes Neural Stem Cell Proliferation and Differentiation following Hypoxic-Ischemic Injury.
Ma SM, Chen LX, Lin YF, Yan H, Lv JW, Xiong M, Li J, Cheng GQ, Yang Y, Qiu ZL, Zhou WH., Free PMC Article | 01/16/2016 |
| Excessive periostin expression contributes to cardiomyocytes senescence. | Ageing related periostin expression increase from cardiac fibroblasts promotes cardiomyocytes senescent.
Li Q, Liu X, Wei J. | 02/28/2015 |
| that periostin, a mediator with deleterious impact on conditions exhibiting fibrosis, is also produced and secreted by myoblasts and regenerating myofibers during architectural remodeling in the course of development and regeneration | Periostin is temporally expressed as an extracellular matrix component in skeletal muscle regeneration and differentiation.
Ozdemir C, Akpulat U, Sharafi P, Yıldız Y, Onbaşılar I, Kocaefe C. | 02/7/2015 |
| POSTN plays an essential role in axonal regeneration | Astroglial-derived periostin promotes axonal regeneration after spinal cord injury.
Shih CH, Lacagnina M, Leuer-Bisciotti K, Pröschel C., Free PMC Article | 04/5/2014 |
| PN might play an important role during the healing process of a full-thickness cutaneous wound. | [The expressions of periostin and the related factors during healing process of full-thickness cutaneous wound in rat].
Hou JJ, Nie FF, Li BL, Zhao X, Qin ZL, Ma YG, Li JN. | 08/3/2013 |
| Periostin overexpression is associated with kidney injury. | Periostin: novel tissue and urinary biomarker of progressive renal injury induces a coordinated mesenchymal phenotype in tubular cells.
Satirapoj B, Wang Y, Chamberlin MP, Dai T, LaPage J, Phillips L, Nast CC, Adler SG., Free PMC Article | 12/22/2012 |
| periostin as a previously unrecognized marker associated with disease progression and regression in hypertensive nephropathy | Identification of periostin as a critical marker of progression/reversal of hypertensive nephropathy.
Guerrot D, Dussaule JC, Mael-Ainin M, Xu-Dubois YC, Rondeau E, Chatziantoniou C, Placier S., Free PMC Article | 07/14/2012 |
| High periostin is associated with fibrogenesis in experimental renal insufficiency. | Left ventricular periostin gene expression is associated with fibrogenesis in experimental renal insufficiency.
Pohjolainen V, Rysä J, Näpänkangas J, Kööbi P, Eräranta A, Ilves M, Serpi R, Pörsti I, Ruskoaho H. | 06/2/2012 |