Epigenetic Repression of RUNX2 and OSX Promoters Controls the Nonmineralized State of the Periodontal Ligament. | Epigenetic Repression of RUNX2 and OSX Promoters Controls the Nonmineralized State of the Periodontal Ligament. Gopinathan G, Luan X, Diekwisch TGH., Free PMC Article | 02/14/2023 |
Diminished arachidonate 5-lipoxygenase perturbs phase separation and transcriptional response of Runx2 to reverse pathological ventricular remodeling. | Diminished arachidonate 5-lipoxygenase perturbs phase separation and transcriptional response of Runx2 to reverse pathological ventricular remodeling. Xie S, Chen M, Fang W, Liu S, Wu Q, Liu C, Xing Y, Shi W, Xu M, Zhang M, Chen S, Zeng X, Wang S, Deng W, Tang Q., Free PMC Article | 01/14/2023 |
Parathyroid Hormone-regulation of Runx2 by MiR-290 for Matrix Metalloproteinase-13 Expression in Rat Osteoblastic Cells. | Parathyroid Hormone-regulation of Runx2 by MiR-290 for Matrix Metalloproteinase-13 Expression in Rat Osteoblastic Cells. Akshaya N, Srinaath N, Rohini M, Ilangovan R, Selvamurugan N. | 06/11/2022 |
Regulation of transforming growth factor-beta1-stimulation of Runx2 acetylation for matrix metalloproteinase 13 expression in osteoblastic cells. | Regulation of transforming growth factor-β1-stimulation of Runx2 acetylation for matrix metalloproteinase 13 expression in osteoblastic cells. Gomathi K, Rohini M, Partridge NC, Selvamurugan N. | 05/14/2022 |
LncRNA H19 sponges miR-103-3p to promote the high phosphorus-induced osteoblast phenotypic transition of vascular smooth muscle cells by upregulating Runx2. | LncRNA H19 sponges miR-103-3p to promote the high phosphorus-induced osteoblast phenotypic transition of vascular smooth muscle cells by upregulating Runx2. Zhou W, Feng Q, Cheng M, Zhang D, Jin J, Zhang S, Bai Y, Xu J. | 04/9/2022 |
Induction of cardiomyocyte calcification is dependent on FoxO1/NFATc3/Runx2 signaling. | Induction of cardiomyocyte calcification is dependent on FoxO1/NFATc3/Runx2 signaling. Samanta J, Mondal A, Das S, Chakraborty S, Sengupta A. | 03/26/2022 |
MiR-320b negatively regulates ovariectomy-induced osteoporosis in rats by decreasing RUNX2. | MiR-320b negatively regulates ovariectomy-induced osteoporosis in rats by decreasing RUNX2. Zhang L, Yao Z, Liu M, Liu Y. | 03/19/2022 |
miRNA320a-3p/RUNX2 signal programming mediates the transgenerational inheritance of inhibited ovarian estrogen synthesis in female offspring rats induced by prenatal dexamethasone exposure. | miRNA320a-3p/RUNX2 signal programming mediates the transgenerational inheritance of inhibited ovarian estrogen synthesis in female offspring rats induced by prenatal dexamethasone exposure. Gong X, Zhang J, Ge C, Yi Y, Dai S, Fan G, Li C, Zhang Y, Wang H, Xu D. | 12/25/2021 |
Spatio-temporal immunolocalization of VEGF-A, Runx2, and osterix during the early steps of intramembranous ossification of the alveolar process in rat embryos. | Spatio-temporal immunolocalization of VEGF-A, Runx2, and osterix during the early steps of intramembranous ossification of the alveolar process in rat embryos. da Silva Sasso GR, Florencio-Silva R, Sasso-Cerri E, Gil CD, de Jesus Simões M, Cerri PS. | 10/16/2021 |
Cbfa1 expression in vascular smooth muscle cells may be elevated by increased nitric oxide/iNOS. | Cbfa1 expression in vascular smooth muscle cells may be elevated by increased nitric oxide/iNOS. Gloria MAD, Mouro MG, Geraldini S, Higa EMS, Carvalho AB., Free PMC Article | 08/14/2021 |
Expression of RUNX2 and Osterix in Rat Mesenchymal Stem Cells during Culturing in Osteogenic-Conditioned Medium. | Expression of RUNX2 and Osterix in Rat Mesenchymal Stem Cells during Culturing in Osteogenic-Conditioned Medium. Pokrovskaya LA, Nadezhdin SV, Zubareva EV, Burda YE, Gnezdyukova ES. | 07/10/2021 |
BMP2-mimicking peptide modified with E7 coupling to calcined bovine bone enhanced bone regeneration associating with activation of the Runx2/SP7 signaling axis. | BMP2-mimicking peptide modified with E7 coupling to calcined bovine bone enhanced bone regeneration associating with activation of the Runx2/SP7 signaling axis. Xi Y, Miao X, Li Y, Lai K, Du X, Jiang Z, Wang Y, Yang G. | 07/3/2021 |
ROCK-TAZ signaling axis regulates mechanical tension-induced osteogenic differentiation of rat cranial sagittal suture mesenchymal stem cells. | ROCK-TAZ signaling axis regulates mechanical tension-induced osteogenic differentiation of rat cranial sagittal suture mesenchymal stem cells. Li W, Zhao J, Wang J, Sun L, Xu H, Sun W, Pan Y, Wang H, Zhang WB. | 03/13/2021 |
miR-873-3p targets HDAC4 to stimulate matrix metalloproteinase-13 expression upon parathyroid hormone exposure in rat osteoblasts. | miR-873-3p targets HDAC4 to stimulate matrix metalloproteinase-13 expression upon parathyroid hormone exposure in rat osteoblasts. Malavika D, Shreya S, Raj Priya V, Rohini M, He Z, Partridge NC, Selvamurugan N. | 03/13/2021 |
MiR-137 affects bone mineral density in osteoporosis rats through regulating RUNX2. | MiR-137 affects bone mineral density in osteoporosis rats through regulating RUNX2. Cai WL, Zeng W, Zhu BY, Liu HH, Liu JL. | 02/13/2021 |
Lysine-Specific Demethylase 4A Regulates Osteogenic Differentiation via Regulating the Binding Ability of H3K9me3 with the Promoters of Runx2, Osterix and Osteocalcin. | Lysine-Specific Demethylase 4A Regulates Osteogenic Differentiation via Regulating the Binding Ability of H3K9me3 with the Promoters of Runx2, Osterix and Osteocalcin. Qin G, Li Y, Wang H, Yang J, Chen Q, Tang H, Wang Y, Zhang M, Jiang T, Lin S, Huo S. | 11/28/2020 |
Notch Signaling Regulates MMP-13 Expression via Runx2 in Chondrocytes. | Notch Signaling Regulates MMP-13 Expression via Runx2 in Chondrocytes. Xiao D, Bi R, Liu X, Mei J, Jiang N, Zhu S., Free PMC Article | 11/21/2020 |
Glucose Fluctuations Promote Aortic Fibrosis through the ROS/p38 MAPK/Runx2 Signaling Pathway. | Glucose Fluctuations Promote Aortic Fibrosis through the ROS/p38 MAPK/Runx2 Signaling Pathway. Zhang ZY, Wang N, Qian LL, Miao LF, Dang SP, Wu Y, Wang RX. | 09/12/2020 |
Our findings demonstrated that cyclic stretch suppresses miR-129-1-3p expression, which in turn activates Runx2 and VEGF to promote endothelial differentiation of EPCs and angiogenesis. Therefore, targeting miR-129-1-3p and Runx2 may be a potential therapeutic strategy for treating vessel injury. | MicroRNA-129-1-3p regulates cyclic stretch-induced endothelial progenitor cell differentiation by targeting Runx2. Li N, Wang WB, Bao H, Shi Q, Jiang ZL, Qi YX, Han Y. | 07/18/2020 |
Gingival stromal progenitor cells cultured in Platelet rich fibrin had potential osteogenic differentiation ability predicted by the CBF-alpha1/sox9 ratio. | Osteogenic potential of gingival stromal progenitor cells cultured in platelet rich fibrin is predicted by core-binding factor subunit-α1/Sox9 expression ratio ( in vitro). Nugraha AP, Narmada IB, Ernawati DS, Dinaryanti A, Hendrianto E, Ihsan IS, Riawan W, Rantam FA., Free PMC Article | 09/7/2019 |
Runx2 promoted the migration of Schwann cells and outgrowth of neurites following sciatic nerve crush. | Runx2 was Correlated with Neurite Outgrowth and Schwann Cell Differentiation, Migration After Sciatic Nerve Crush. Ding D, Zhang P, Liu Y, Wang Y, Sun W, Yu Z, Cheng Z, Wang Y. | 05/25/2019 |
FoxO1 and Runx2 play a role in the reconstruction of periodontal tissue during orthodontic movement of teeth, and they are mainly involved in the process of osteoblast formation and bone formation. | [Expression of Forkhead boxO1 and Runt-related transcription factor 2 in periodontal tissue during orthodontic movement of teeth in rats]. Zhou C, Long SC, Huang L, Dai HW. | 03/2/2019 |
that cross-talk between cAMP/PKA signaling and RUNX2 promotes a malignant phenotype of glioma cells | RUNX2 Promotes Malignant Progression in Glioma. Yamada D, Fujikawa K, Kawabe K, Furuta T, Nakada M, Takarada T. | 12/22/2018 |
Results indicate that Runx2 alleviates high glucose-induced inhibition of osteoblast differentiation by modulating PI3K/AKT/GSK3beta/beta-catenin pathway. | Runx2 alleviates high glucose-suppressed osteogenic differentiation via PI3K/AKT/GSK3β/β-catenin pathway. Chen Y, Hu Y, Yang L, Zhou J, Tang Y, Zheng L, Qin P. | 04/14/2018 |
TGF-beta1 stimulates the phosphorylation of Runx2 at three serine amino acids, and this event is required for MMP-13 expression in osteoblastic cells. | Characterization of Runx2 phosphorylation sites required for TGF-β1-mediated stimulation of matrix metalloproteinase-13 expression in osteoblastic cells. Arumugam B, Vairamani M, Partridge NC, Selvamurugan N. | 11/26/2017 |