| Underrepresentation of activating KIR gene expression in single-cell RNA-seq data is due to KIR gene misassignment. | Underrepresentation of activating KIR gene expression in single-cell RNA-seq data is due to KIR gene misassignment.
Alves E, Chopra A, Ram R, Currenti J, Kalams SA, Mallal SA, Phillips EJ, Gaudieri S. | 01/31/2024 |
| KIR2DL4/HLA-G polymorphisms were associated with HCV infection susceptibility among Chinese high-risk population. | KIR2DL4/HLA-G polymorphisms were associated with HCV infection susceptibility among Chinese high-risk population.
Feng Z, Huang P, Zhang J, Xia X, Zhang AM, Zeng T, Chen Q, Zhu C, Tan W, Zhang Y, Yue M. | 03/30/2023 |
| Clinical significance and immune landscape of KIR2DL4 and the senescence-based signature in cutaneous melanoma. | Clinical significance and immune landscape of KIR2DL4 and the senescence-based signature in cutaneous melanoma.
Mao R, Ren Z, Yang F, Yang P, Zhang T., Free PMC Article | 11/12/2022 |
| Roles of HLA-G/KIR2DL4 in Breast Cancer Immune Microenvironment. | Roles of HLA-G/KIR2DL4 in Breast Cancer Immune Microenvironment.
Zheng G, Jia L, Yang AG., Free PMC Article | 04/2/2022 |
| Interaction between HLA-G and NK cell receptor KIR2DL4 orchestrates HER2-positive breast cancer resistance to trastuzumab. | Interaction between HLA-G and NK cell receptor KIR2DL4 orchestrates HER2-positive breast cancer resistance to trastuzumab.
Zheng G, Guo Z, Li W, Xi W, Zuo B, Zhang R, Wen W, Yang AG, Jia L., Free PMC Article | 03/12/2022 |
| KIR2DL4 promotes the proliferation of RCC cell associated with PI3K/Akt signaling activation. | KIR2DL4 promotes the proliferation of RCC cell associated with PI3K/Akt signaling activation.
Ding XF, Chen J, Ma HL, Liang Y, Wang YF, Zhang HT, Li X, Chen G. | 02/26/2022 |
| Expression of HLA-G and KIR2DL4 receptor in chorionic villous in missed abortion. | Expression of HLA-G and KIR2DL4 receptor in chorionic villous in missed abortion.
Bespalova O, Bakleicheva M, Ivashchenko T, Tral T, Tolibova G, Kogan I. | 10/16/2021 |
| Possible roles of HLA-G regulating immune cells in pregnancy and endometrial diseases via KIR2DL4. | Possible roles of HLA-G regulating immune cells in pregnancy and endometrial diseases via KIR2DL4.
Bai Y, Liang J, Liu W, Wang F, Li C. | 09/25/2021 |
| Family-based exome sequencing identifies rare coding variants in age-related macular degeneration. | Family-based exome sequencing identifies rare coding variants in age-related macular degeneration.
Ratnapriya R, Acar İE, Geerlings MJ, Branham K, Kwong A, Saksens NTM, Pauper M, Corominas J, Kwicklis M, Zipprer D, Starostik MR, Othman M, Yashar B, Abecasis GR, Chew EY, Ferrington DA, Hoyng CB, Swaroop A, den Hollander AI., Free PMC Article | 08/28/2021 |
| Altered oxidative stress markers in relation to T cells, NK cells & killer immunoglobulin receptors that are associated with disease activity in SLE patients. | Altered oxidative stress markers in relation to T cells, NK cells & killer immunoglobulin receptors that are associated with disease activity in SLE patients.
Tandon A, Anupam K, Kaushal J, Gautam P, Sharma A, Bhatnagar A. | 07/31/2021 |
| Killer Immunoglobulin-Like Receptor 2DL4 (CD158d) Regulates Human Mast Cells both Positively and Negatively: Possible Roles in Pregnancy and Cancer Metastasis. | Killer Immunoglobulin-Like Receptor 2DL4 (CD158d) Regulates Human Mast Cells both Positively and Negatively: Possible Roles in Pregnancy and Cancer Metastasis.
Kataoka TR, Ueshima C, Hirata M, Minamiguchi S, Haga H., Free PMC Article | 11/21/2020 |
| Have higher frequencies of the KIR2DL4 positive population. | KIR2DL4-HLAG interaction at human NK cell-oligodendrocyte interfaces regulates IFN-γ-mediated effects.
Banerjee PP, Pang L, Soldan SS, Miah SM, Eisenberg A, Maru S, Waldman A, Smith EA, Rosenberg-Hasson Y, Hirschberg D, Smith A, Ablashi DV, Campbell KS, Orange JS., Free PMC Article | 01/18/2020 |
| The allelic diversity of the KIR2DL4 receptor locus showed no significant association with leukemia among ethnic Hans from southern China. | [Association of polymorphisms of KIR2DL4 gene with leukemia among ethnic Hans from southern China].
Chen R, Deng Z. | 06/9/2018 |
| Data show that most of the Langerhans cell histiocytosis (LCH)cases were positive for KIR2DL4, suggesting that KIR2DL4 may serve as a marker for LCH diagnosis. | Killer cell immunoglobulin-like receptor 2DL4 is expressed in and suppresses the cell growth of Langerhans cell histiocytosis.
Takei Y, Ueshima C, Kataoka TR, Hirata M, Sugimoto A, Rokutan-Kurata M, Moriyoshi K, Ono K, Murakami I, Iwamoto S, Haga H., Free PMC Article | 03/24/2018 |
| KIR 2D (L1, L3, L4, S4) and KIR 3DL1 expression was correlated with poor prognosis in non-small cell lung carcinoma patients. | KIR 2D (L1, L3, L4, S4) and KIR 3DL1 protein expression in non-small cell lung cancer.
He Y, Bunn PA, Zhou C, Chan D., Free PMC Article | 02/17/2018 |
| Data show the alignment of different KIR2DL4 receptor alleles with ADOMA. | ADOMA: A Command Line Tool to Modify ClustalW Multiple Alignment Output.
Zaal D, Nota B. | 02/3/2018 |
| Serum levels of soluble HLA-G were similar in CMV- and CMV+ subjects but levels in culture supernatants were significantly higher in cells from CMV+ than from CMV- subjects stimulated with CMV antigens. The HLA-G ligand KIR2DL4 was mainly expressed on NK cells and CD56+ T cells with no differences between CMV+ and CMV- subjects. | The Influence of Cytomegalovirus on Expression of HLA-G and its Ligand KIR2DL4 by Human Peripheral Blood Leucocyte Subsets.
Albayati Z, Alyami A, Alomar S, Middleton D, Bonnett L, Aleem S, Flanagan BF, Christmas SE. | 10/28/2017 |
| a woman's heterozygosity in HLA-G and LILRB1 might be an advantage for a success of reproduction, but the partner's heterozygosity in 9A/10A KIR2DL4 alleles might not | Possible Role of HLA-G, LILRB1 and KIR2DL4 Gene Polymorphisms in Spontaneous Miscarriage.
Nowak I, Malinowski A, Barcz E, Wilczyński JR, Wagner M, Majorczyk E, Motak-Pochrzęst H, Banasik M, Kuśnierczyk P., Free PMC Article | 02/18/2017 |
| Decreased level of KIR2DL4 rather than its single nucleotide polymorphism is correlated with the susceptibility of pre-eclampsia | KIR2DL4 expression rather than its single nucleotide polymorphisms correlates with pre-eclampsia.
Wang D, Tian Y, Zhao Y, Liu L, Liu X, Wu F., Free PMC Article | 10/29/2016 |
| the KIR2DL4 on human mast cells facilitates HLA-G-expressing cancer invasion and the subsequent metastasis. | The Killer Cell Ig-like Receptor 2DL4 Expression in Human Mast Cells and Its Potential Role in Breast Cancer Invasion.
Ueshima C, Kataoka TR, Hirata M, Furuhata A, Suzuki E, Toi M, Tsuruyama T, Okayama Y, Haga H. | 05/7/2016 |
| Among 438 Polish people, a weak difference was seen between males and females in 9769 C/A genotypes and alleles. Fertile women had a high frequency of homozygosity for the defective 9A variant, so KIR2DL4 is not absolutely necessary for reproduction. | Genetic polymorphism of KIR2DL4 in the Polish population.
Nowak I, Barcz E, Majorczyk E, Malinowski A, Wilczyński JR, Banasik M, Motak-Pochrzęst H, Kuśnierczyk P. | 04/23/2016 |
| The 9620 9A/10A (rs11410751) polymorphism in exon 7 did not influence the risk of NSCLC. | Genetic polymorphisms and expression of HLA-G and its receptors, KIR2DL4 and LILRB1, in non-small cell lung cancer.
Wiśniewski A, Kowal A, Wyrodek E, Nowak I, Majorczyk E, Wagner M, Pawlak-Adamska E, Jankowska R, Ślesak B, Frydecka I, Kuśnierczyk P. | 04/23/2016 |
| Array CGH showed a 95 Kb de novo duplication on chromosome 19q13.4 encompassing four killer cell immunoglobulin-like receptor (KIR) genes. | Partial duplication of chromosome 19 associated with syndromic duane retraction syndrome.
Abu-Amero KK, Kondkar AA, Al Otaibi A, Alorainy IA, Khan AO, Hellani AM, Oystreck DT, Bosley TM. | 08/8/2015 |
| Results show that HLA-E and KIR2DL4 demonstrate evidence of positive selection between human, chimpanzee and gorilla suggesting a main role for immunological adaptations linked to embryo deep invasion of the maternal endometrium during pregnancy. | Adaptive evolution at immune system genes and deep pregnancy implantation in primates.
Civetta A. | 07/25/2015 |
| The unique functional properties of KIR2DL4 may be mediated by self-association of the receptor. | The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.
Moradi S, Berry R, Pymm P, Hitchen C, Beckham SA, Wilce MC, Walpole NG, Clements CS, Reid HH, Perugini MA, Brooks AG, Rossjohn J, Vivian JP., Free PMC Article | 06/20/2015 |