Brain-specific serine/threonine-protein kinase 1 is a substrate of protein kinase C epsilon involved in sex-specific ethanol and anxiety phenotypes. | Brain-specific serine/threonine-protein kinase 1 is a substrate of protein kinase C epsilon involved in sex-specific ethanol and anxiety phenotypes. Dugan MP, Maiya R, Fleischer C, Bajo M, Snyder AE, Koduri A, Srinivasan S, Roberto M, Messing RO., Free PMC Article | 03/22/2024 |
Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex. | Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex. Nakanishi K, Niida H, Tabata H, Ito T, Hori Y, Hattori M, Johmura Y, Yamada C, Ueda T, Takeuchi K, Yamada K, Nagata KI, Wakamatsu N, Kishi M, Pan YA, Ugawa S, Shimada S, Sanes JR, Higashi Y, Nakanishi M., Free PMC Article | 10/10/2020 |
CAST/SAD-B reaction serves as a brake on synaptic transmission | SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression. Mochida S, Hida Y, Tanifuji S, Hagiwara A, Hamada S, Abe M, Ma H, Yasumura M, Kitajima I, Sakimura K, Ohtsuka T. | 11/18/2017 |
Structure and inhibition analysis of the mouse SAD-B C-terminal fragment | Structure and inhibition analysis of the mouse SAD-B C-terminal fragment. Ma H, Wu JX, Wang J, Wang ZX, Wu JW. | 02/4/2017 |
At mature pre-synaptic terminals, SAD-B regulates vesicular release probability and synaptic plasticity. | SAD-B kinase regulates pre-synaptic vesicular dynamics at hippocampal Schaffer collateral synapses and affects contextual fear memory. Watabe AM, Nagase M, Hagiwara A, Hida Y, Tsuji M, Ochiai T, Kato F, Ohtsuka T. | 04/30/2016 |
SAD-A and SAD-B kinases have multiple, sequential roles in axonal differentiation | SAD kinases control the maturation of nerve terminals in the mammalian peripheral and central nervous systems. Lilley BN, Krishnaswamy A, Wang Z, Kishi M, Frank E, Sanes JR., Free PMC Article | 03/29/2014 |
SAD kinase may regulate neurotransmitter release from motor end plates in a similar manner to its regulation of neurotransmitter release in the central nervous system. | Distribution of serine/threonine kinase SAD-B in mouse peripheral nerve synapse. Hagiwara A, Harada K, Hida Y, Kitajima I, Ohtsuka T. | 03/31/2012 |
The regulation of Wee1 by SadA and SadB kinases is essential for the differentiation of polarized neurons. | Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity. Müller M, Lutter D, Püschel AW. | 03/8/2010 |
SADB kinase activity controls centrosome homeostasis by regulating phosphorylation of gamma-tubulin. | SADB phosphorylation of gamma-tubulin regulates centrosome duplication. Alvarado-Kristensson M, Rodríguez MJ, Silió V, Valpuesta JM, Carrera AC. | 01/21/2010 |
results show that SAD-A and SAD-B, mammalian orthologs of a kinase needed for presynaptic differentiation in Caenorhabditis elegans, are required for neuronal polarization. | Mammalian SAD kinases are required for neuronal polarization. Kishi M, Pan YA, Crump JG, Sanes JR. | 01/21/2010 |
Once activated, LKB1 phosphorylates and thereby activates SAD-A and SAD-B kinases, which are also required for neuronal polarization in the cerebral cortex. | LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Barnes AP, Lilley BN, Pan YA, Plummer LJ, Powell AW, Raines AN, Sanes JR, Polleux F. | 01/21/2010 |