| MiR-18a affects hypoxia induced glucose metabolism transition in HT22 hippocampal neuronal cell line through the Hif1a gene. | MiR-18a affects hypoxia induced glucose metabolism transition in HT22 hippocampal neuronal cell line through the Hif1a gene.
Liu C, Liu G, Zuo X, Qu D, Sun Y, Liu L, Zhao X, Li J, Cai L., Free PMC Article | 07/1/2024 |
| MiR-18 regulates lipid metabolism of non-alcoholic fatty liver disease via IGF1. | MiR-18 regulates lipid metabolism of non-alcoholic fatty liver disease via IGF1.
Yang H, Zhang B, Yu C. | 05/16/2024 |
| MicroRNA-18a regulates the Pyroptosis, Apoptosis, and Necroptosis (PANoptosis) of osteoblasts induced by tumor necrosis factor-alpha via hypoxia-inducible factor-1alpha. | MicroRNA-18a regulates the Pyroptosis, Apoptosis, and Necroptosis (PANoptosis) of osteoblasts induced by tumor necrosis factor-α via hypoxia-inducible factor-1α.
Zhang W, Xia CL, Qu YD, Li JX, Liu JB, Ou SJ, Yang Y, Qi Y, Xu CP. | 02/13/2024 |
| [miR-18a ameliorates inflammation and tissue injury in a mouse model of allergic rhinitis via blocking TLR4/NF-kappaB pathway]. | [miR-18a ameliorates inflammation and tissue injury in a mouse model of allergic rhinitis via blocking TLR4/NF-κB pathway].
Yang J, Li Q, Wang L, Xie H. | 08/3/2023 |
| miR-181c-5p suppresses neuronal pyroptosis via NLRP1 in Alzheimer's disease. | miR-181c-5p suppresses neuronal pyroptosis via NLRP1 in Alzheimer's disease.
Wang T, Long Q, Hu Y, Yang Y, Li X, Wei H. | 05/8/2023 |
| Long noncoding RNA CASC2 protect ROS-induced oxidative stress in myocardial infarction by miR-18a/SIRT2. | Long noncoding RNA CASC2 protect ROS-induced oxidative stress in myocardial infarction by miR-18a/SIRT2.
Ying G, Tang Z, Zhang J, Zeng J, Zheng Z, Zhang W, Ding L, Wen T, Yi D. | 01/28/2023 |
| miR-18a-3p Encourages Apoptosis of Chondrocyte in Osteoarthritis via HOXA1 Pathway. | miR-18a-3p Encourages Apoptosis of Chondrocyte in Osteoarthritis via HOXA1 Pathway.
Ding B, Xu S, Sun X, Gao J, Nie W, Xu H. | 08/14/2021 |
| miR-18a promotes Mycobacterial survival in macrophages via inhibiting autophagy by down-regulation of ATM. | miR-18a promotes Mycobacterial survival in macrophages via inhibiting autophagy by down-regulation of ATM.
Yuan Q, Chen H, Yang Y, Fu Y, Yi Z., Free PMC Article | 04/24/2021 |
| MEG3 exacerbated TXNIP expression via targeting miR-18a in hyperoxia-induced lung injury | Knockdown of Long Noncoding RNAs of Maternally Expressed 3 Alleviates Hyperoxia-Induced Lung Injury via Inhibiting Thioredoxin-Interacting Protein-Mediated Pyroptosis by Binding to miR-18a.
Zou DM, Zhou SM, Li LH, Zhou JL, Tang ZM, Wang SH. | 06/27/2020 |
| Exosomes from ACE2-expressing endothelial progenitor cells protect ageing endothelial cells against hypoxia/reoxygenation-induced injury through the miR-18a/Nox2/ROS pathway. | ACE2-EPC-EXs protect ageing ECs against hypoxia/reoxygenation-induced injury through the miR-18a/Nox2/ROS pathway.
Zhang C, Wang J, Ma X, Wang W, Zhao B, Chen Y, Chen C, Bihl JC., Free PMC Article | 10/19/2019 |
| Data show that indoleamine 2,3 dioxygenase-1 (IDO1)/ miR-18a/ killer cell lectin-like receptor subfamily K (NKG2D/NKG2DL) regulatory axis in the regulation of NK cell function. | IDO1 impairs NK cell cytotoxicity by decreasing NKG2D/NKG2DLs via promoting miR-18a.
Zhang J, Han X, Hu X, Jin F, Gao Z, Yin L, Qin J, Yin F, Li C, Wang Y. | 05/4/2019 |
| miR-18a was decreased during lung fibrosis in vitro and in vivo, as well as in patients with IPF. Moreover, knockdown of miR-18a led to fibrogenesis in lung fibroblasts, whereas enhanced expression of miR-18a attenuated TGF-beta1-induced lung fibrosis by directly targeting the regulation of connecting tissue growth factor. | lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a.
Li X, Yu T, Shan H, Jiang H, Sun J, Zhao X, Su W, Yang L, Shan H, Liang H. | 04/6/2019 |
| miR-18a participates in the regulation of proliferation by partly decreasing the expression of Fgf1. | MiR-18a regulates myoblasts proliferation by targeting Fgf1.
Liu C, Chen M, Wang M, Pi W, Li N, Meng Q., Free PMC Article | 02/9/2019 |
| in adult pancreatic progenitors, miR-18a inhibits cell proliferation and induces cell cycle arrest by targeting the expressions of CTGF, Nedd9, and CDK19, further counteracting the activation of AKT and ERK signaling | miR-18a counteracts AKT and ERK activation to inhibit the proliferation of pancreatic progenitor cells.
Li X, Zhang Z, Li Y, Zhao Y, Zhai W, Yang L, Kong D, Wu C, Chen Z, Teng CB., Free PMC Article | 11/10/2018 |
| Overexpression of miR-18a-5p in podocytes resulted in significant inhibition of cleaved-caspase 3 protein, and increased the ratio of LC3-II/LC3-I and ATM protein was a target of mir-18a-5p. | Resveratrol transcriptionally regulates miRNA-18a-5p expression ameliorating diabetic nephropathy via increasing autophagy.
Xu XH, Ding DF, Yong HJ, Dong CL, You N, Ye XL, Pan ML, Ma JH, You Q, Lu YB. | 08/11/2018 |
| miR-18a suppresses the expression of Igf1 in a 3'UTR-dependent manner | miR-18a induces myotubes atrophy by down-regulating IgfI.
Liu C, Wang M, Chen M, Zhang K, Gu L, Li Q, Yu Z, Li N, Meng Q. | 11/18/2017 |
| The data showed that the overexpression of miR-18a-5p could downregulate Notch2 expression and subsequently suppress endothelial-mesenchymal transition and cardiac fibrosis. | MiR-18a-5p inhibits endothelial-mesenchymal transition and cardiac fibrosis through the Notch2 pathway.
Geng H, Guan J. | 08/26/2017 |
| these data suggest that The Kampo medicine Yokukansan normalizes glucocorticoid receptor protein levels by regulating miR-18 expression in the hypothalamus, thus normalizing hypothalamic-pituitary-adrenal A axis activity following stress exposure. | The Kampo Medicine Yokukansan Decreases MicroRNA-18 Expression and Recovers Glucocorticoid Receptors Protein Expression in the Hypothalamus of Stressed Mice.
Shimizu S, Tanaka T, Takeda T, Tohyama M, Miyata S., Free PMC Article | 03/19/2016 |
| miRNA18a expression was increased in mammary epithelial cells grown on stiff substrate, which promotes malignant progression via miRNA18a regulation of PTEN and HOXA9. | Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.
Mouw JK, Yui Y, Damiano L, Bainer RO, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen YY, Weaver VM., Free PMC Article | 05/31/2014 |
| let-7 and miR-18 down-regulate Acvr1b and Smad2, respectively, to attenuate Nodal responsiveness and bias blastomeres to ectoderm and mesoderm fates | Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis.
Colas AR, McKeithan WL, Cunningham TJ, Bushway PJ, Garmire LX, Duester G, Subramaniam S, Mercola M., Free PMC Article | 01/26/2013 |
| miR-18a plays a fine-tuning role in regulating pancreatic progenitors and exocrine cells through the repression of Ptf1a expression. | MiR-18a regulates expression of the pancreatic transcription factor Ptf1a in pancreatic progenitor and acinar cells.
Yang Y, Ding L, An Y, Zhang ZW, Lang Y, Tai S, Guo F, Teng CB. | 04/14/2012 |
| results reveal that miR-18 regulates heat shock factor 2 (HSF2) activity in spermatogenesis and link miR-18 to HSF2-mediated physiological processes such as male germ cell maturation. | miR-18, a member of Oncomir-1, targets heat shock transcription factor 2 in spermatogenesis.
Björk JK, Sandqvist A, Elsing AN, Kotaja N, Sistonen L. | 10/23/2010 |