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    Mir146 microRNA 146 [ Mus musculus (house mouse) ]

    Gene ID: 387164, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Dysregulation of miR-223, miR-146a, and miR-193a Expression Profile in Acute and Chronic Phases of Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice.

    Dysregulation of miR-223, miR-146a, and miR-193a Expression Profile in Acute and Chronic Phases of Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice.
    Gharibi S, Moghimi B, Mahmoudi MB, Shahvazian E, Yazd EF, Yadegari M, Tahoori MT, Yazdanpanah E, Haghmorad D, Oksenych V., Free PMC Article

    11/5/2024
    Unraveling the Impact of miR-146a in Pulmonary Arterial Hypertension Pathophysiology and Right Ventricular Function.

    Unraveling the Impact of miR-146a in Pulmonary Arterial Hypertension Pathophysiology and Right Ventricular Function.
    Santos-Gomes J, Mendes-Ferreira P, Adão R, Maia-Rocha C, Rego B, Poels M, Saint-Martin Willer A, Masson B, Provencher S, Bonnet S, Montani D, Perros F, Antigny F, Leite-Moreira AF, Brás-Silva C., Free PMC Article

    09/19/2024
    Plasma exosomes carrying mmu-miR-146a-5p and Notch signalling pathway-mediated synaptic activity in schizophrenia.

    Plasma exosomes carrying mmu-miR-146a-5p and Notch signalling pathway-mediated synaptic activity in schizophrenia.
    Wang Z, Wu T, Hu H, Alabed AAA, Cui G, Sun L, Sun Z, Wang Y, Li P., Free PMC Article

    09/11/2024
    miR-146a Decreases Inflammation and ROS Production in Aged Dermal Fibroblasts.

    miR-146a Decreases Inflammation and ROS Production in Aged Dermal Fibroblasts.
    Zhang L, Wang IC, Meng S, Xu J., Free PMC Article

    08/9/2024
    MicroRNA-146b protects kidney injury during urinary tract infections by modulating macrophage polarization.

    MicroRNA-146b protects kidney injury during urinary tract infections by modulating macrophage polarization.
    Wang C, Cheng H, Yan F, Zhang H, Zhang J, Li C, Zhao M, Shi D, Xiong H., Free PMC Article

    07/30/2024
    TLR8-activating miR-146a-3p is an intermediate signal contributing to fetal membrane inflammation in response to bacterial LPS.

    TLR8-activating miR-146a-3p is an intermediate signal contributing to fetal membrane inflammation in response to bacterial LPS.
    Georges HM, Cassin C, Tong M, Abrahams VM.,

    07/26/2024
    miRNA-146a-5p Inhibits Hypoxia-Induced Myocardial Fibrosis Through EndMT.

    miRNA-146a-5p Inhibits Hypoxia-Induced Myocardial Fibrosis Through EndMT.
    Wang Y, Yu J, Ou C, Zhao Y, Chen L, Cai W, Wang H, Huang S, Hu J, Sun G, Li L.

    06/28/2024
    MiR-146a alleviates inflammatory bowel disease in mice through systematic regulation of multiple genetic networks.

    MiR-146a alleviates inflammatory bowel disease in mice through systematic regulation of multiple genetic networks.
    Zhu F, Yang T, Ning M, Liu Y, Xia W, Fu Y, Wen T, Zheng M, Xia R, Qian R, Li Y, Sun M, Liu J, Tian L, Zhou Q, Yu X, Peng C., Free PMC Article

    06/5/2024
    The bone mesenchymal stem cell-derived exosomal miR-146a-5p promotes diabetic wound healing in mice via macrophage M1/M2 polarization.

    The bone mesenchymal stem cell-derived exosomal miR-146a-5p promotes diabetic wound healing in mice via macrophage M1/M2 polarization.
    Zhou X, Ye C, Jiang L, Zhu X, Zhou F, Xia M, Chen Y.

    04/12/2024
    IL-33 Induces Cellular and Exosomal miR-146a Expression as a Feedback Inhibitor of Mast Cell Function.

    IL-33 Induces Cellular and Exosomal miR-146a Expression as a Feedback Inhibitor of Mast Cell Function.
    Taruselli MT, Abdul Qayum A, Abebayehu D, Caslin HL, Dailey JM, Kotha A, Burchett JR, Kee SA, Maldonado TD, Ren B, Chao W, Zou L, Haque TT, Straus D, Ryan JJ., Free PMC Article

    04/5/2024
    MiR-146a alleviates acute lung injury via inhibiting Notch 1 signaling pathway targeting macrophage.

    MiR-146a alleviates acute lung injury via inhibiting Notch 1 signaling pathway targeting macrophage.
    Zhao Q, Wang Y, Zou J, Kuang R, Ji S.

    02/29/2024
    miR-146a regulates emphysema formation and abnormal inflammation in the lungs of two mouse models.

    miR-146a regulates emphysema formation and abnormal inflammation in the lungs of two mouse models.
    Yoshikawa H, Sato T, Horikoshi K, Komura M, Nitta NA, Mitsui A, Koike K, Kodama Y, Takahashi K.

    01/12/2024
    miR-146a-3p as a potential novel therapeutic by targeting MBD2 to mediate Th17 differentiation in Th17 predominant neutrophilic severe asthma.

    miR-146a-3p as a potential novel therapeutic by targeting MBD2 to mediate Th17 differentiation in Th17 predominant neutrophilic severe asthma.
    Duan W, Huang J, Wasti B, Chen Z, Yuan Y, He Y, Li D, Jia J, Liu S, Liu Y, Ma L, Zeng Q, Zhu L, Li J, Zhang X, Xiang X., Free PMC Article

    10/5/2023
    A Feedback Loop Involving Exosomal miR-146a and NG2 to Propel the Development and Progression of Hypothyroidism.

    A Feedback Loop Involving Exosomal miR-146a and NG2 to Propel the Development and Progression of Hypothyroidism.
    Sui F, Chen P, Feng C, Yang Q, Zhang S, Ji M, Wang Y, Guan H, Xing M, Hou P.

    09/19/2023
    miR-146a aggravates cognitive impairment and Alzheimer disease-like pathology by triggering oxidative stress through MAPK signaling.

    miR-146a aggravates cognitive impairment and Alzheimer disease-like pathology by triggering oxidative stress through MAPK signaling.
    Zhan-Qiang H, Hai-Hua Q, Chi Z, Miao W, Cui Z, Zi-Yin L, Jing H, Yi-Wei W.

    09/7/2023
    MicroRNA-146a negatively regulates inflammation via the IRAK1/TRAF6/NF-kappaB signaling pathway in dry eye.

    MicroRNA-146a negatively regulates inflammation via the IRAK1/TRAF6/NF-κB signaling pathway in dry eye.
    Han R, Gao J, Wang L, Hao P, Chen X, Wang Y, Jiang Z, Jiang L, Wang T, Zhu L, Li X., Free PMC Article

    07/13/2023
    MicroRNA-146a Promotes Embryonic Stem Cell Differentiation towards Vascular Smooth Muscle Cells through Regulation of Kruppel-like Factor 4.

    MicroRNA-146a Promotes Embryonic Stem Cell Differentiation towards Vascular Smooth Muscle Cells through Regulation of Kruppel-like Factor 4.
    Zhang Q, Pan RR, Wu YT, Wei YM., Free PMC Article

    05/1/2023
    MiR-146a in ALS: Contribution to Early Peripheral Nerve Degeneration and Relevance as Disease Biomarker.

    MiR-146a in ALS: Contribution to Early Peripheral Nerve Degeneration and Relevance as Disease Biomarker.
    Giagnorio E, Malacarne C, Cavalcante P, Scandiffio L, Cattaneo M, Pensato V, Gellera C, Riva N, Quattrini A, Dalla Bella E, Lauria G, Mantegazza R, Bonanno S, Marcuzzo S., Free PMC Article

    04/10/2023
    microRNA-146a modulates behavioural activity, neuroinflammation, and oxidative stress in adult mice.

    microRNA-146a modulates behavioural activity, neuroinflammation, and oxidative stress in adult mice.
    Zhao W, Spiers JG, Vassileff N, Khadka A, Jaehne EJ, van den Buuse M, Hill AF.

    03/8/2023
    miR-146a-5p promotes epithelium regeneration against LPS-induced inflammatory injury via targeting TAB1/TAK1/NF-kappaB signaling pathway.

    miR-146a-5p promotes epithelium regeneration against LPS-induced inflammatory injury via targeting TAB1/TAK1/NF-κB signaling pathway.
    Chen X, Li W, Chen T, Ren X, Zhu J, Hu F, Luo J, Xing L, Zhou H, Sun J, Jiang Q, Zhang Y, Xi Q.

    01/28/2023
    MiR-146a-5p accelerates sepsis through dendritic cell activation and glycolysis via targeting ATG7.

    MiR-146a-5p accelerates sepsis through dendritic cell activation and glycolysis via targeting ATG7.
    Yu J, Xue J, Liu C, Zhang A, Qin L, Liu J, Yang Y.

    10/22/2022
    Regulation of T-independent B-cell responses by microRNA-146a.

    Regulation of T-independent B-cell responses by microRNA-146a.
    King JK, Tran TM, Paing MH, Yin Y, Jaiswal AK, Tso CH, Roy K, Casero D, Rao DS., Free PMC Article

    10/15/2022
    TLR7 Mediates Acute Respiratory Distress Syndrome in Sepsis by Sensing Extracellular miR-146a.

    TLR7 Mediates Acute Respiratory Distress Syndrome in Sepsis by Sensing Extracellular miR-146a.
    Huang H, Zhu J, Gu L, Hu J, Feng X, Huang W, Wang S, Yang Y, Cui P, Lin SH, Suen A, Shimada BK, Williams B, Kane MA, Ke Y, Zhang CO, Birukova AA, Birukov KG, Chao W, Zou L., Free PMC Article

    09/17/2022
    miR-146a-5p Attenuates Allergic Airway Inflammation by Inhibiting the NLRP3 Inflammasome Activation in Macrophages.

    miR-146a-5p Attenuates Allergic Airway Inflammation by Inhibiting the NLRP3 Inflammasome Activation in Macrophages.
    Yang Y, Huang G, Xu Q, Zhao G, Jiang J, Li Y, Guo Z.

    09/17/2022
    Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage.

    Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage.
    Hsieh YT, Chou YC, Kuo PY, Tsai HW, Yen YT, Shiau AL, Wang CR., Free PMC Article

    09/3/2022
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