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    Mir206 microRNA 206 [ Mus musculus (house mouse) ]

    Gene ID: 387202, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    miR-206-3p Targets Brain-Derived Neurotrophic Factor and Affects Postoperative Cognitive Function in Aged Mice.

    miR-206-3p Targets Brain-Derived Neurotrophic Factor and Affects Postoperative Cognitive Function in Aged Mice.
    Wang S, Zhao J, Wang C, Yao Y, Song Z, Li L, Jiang J.

    08/2/2024
    miRNA-206-3p alleviates LPS-induced acute lung injury via inhibiting inflammation and pyroptosis through modulating TLR4/NF-kappaB/NLRP3 pathway.

    miRNA-206-3p alleviates LPS-induced acute lung injury via inhibiting inflammation and pyroptosis through modulating TLR4/NF-κB/NLRP3 pathway.
    Chen M, Zhang J, Huang H, Wang Z, Gao Y, Liu J., Free PMC Article

    06/12/2024
    USF2 activates RhoB/ROCK pathway by transcriptional inhibition of miR-206 to promote pyroptosis in septic cardiomyocytes.

    USF2 activates RhoB/ROCK pathway by transcriptional inhibition of miR-206 to promote pyroptosis in septic cardiomyocytes.
    Dong W, Liao R, Weng J, Du X, Chen J, Fang X, Liu W, Long T, You J, Wang W, Peng X.

    05/31/2024
    miR-206 alleviates LPS-induced inflammatory injury in cardiomyocytes via directly targeting USP33 to inhibit the JAK2/STAT3 signaling pathway.

    miR-206 alleviates LPS-induced inflammatory injury in cardiomyocytes via directly targeting USP33 to inhibit the JAK2/STAT3 signaling pathway.
    Dong W, Chen J, Wang Y, Weng J, Du X, Fang X, Liu W, Long T, You J, Wang W, Peng X., Free PMC Article

    04/17/2024
    MicroRNA-206 promotes the recruitment of CD8(+) T cells by driving M1 polarisation of Kupffer cells.

    MicroRNA-206 promotes the recruitment of CD8(+) T cells by driving M1 polarisation of Kupffer cells.
    Liu N, Wang X, Steer CJ, Song G., Free PMC Article

    07/16/2022
    Upregulated miR-206 Aggravates Deep Vein Thrombosis by Regulating GJA1-Mediated Autophagy of Endothelial Progenitor Cells.

    Upregulated miR-206 Aggravates Deep Vein Thrombosis by Regulating GJA1-Mediated Autophagy of Endothelial Progenitor Cells.
    Li Y, Ge J, Yin Y, Yang R, Kong J, Gu J., Free PMC Article

    04/9/2022
    Hippocampal miR-206-3p participates in the pathogenesis of depression via regulating the expression of BDNF.

    Hippocampal miR-206-3p participates in the pathogenesis of depression via regulating the expression of BDNF.
    Guan W, Xu DW, Ji CH, Wang CN, Liu Y, Tang WQ, Gu JH, Chen YM, Huang J, Liu JF, Jiang B.

    03/12/2022
    Free Fatty Acid Impairs Myogenic Differentiation through the AMPKalpha-MicroRNA 206 Pathway.

    Free Fatty Acid Impairs Myogenic Differentiation through the AMPKα-MicroRNA 206 Pathway.
    Jiang A, Guo H, Zhang L, Jiang X, Zhang X, Wu W, Liu H., Free PMC Article

    02/26/2022
    Epithelial miR-206 targets CD39/extracellular ATP to upregulate airway IL-25 and TSLP in type 2-high asthma.

    Epithelial miR-206 targets CD39/extracellular ATP to upregulate airway IL-25 and TSLP in type 2-high asthma.
    Zhang K, Feng Y, Liang Y, Wu W, Chang C, Chen D, Chen S, Gao J, Chen G, Yi L, Cheng D, Zhen G., Free PMC Article

    02/19/2022
    Bone marrow mesenchymal stem cell-derived exosomal miR-206 promotes osteoblast proliferation and differentiation in osteoarthritis by reducing Elf3.

    Bone marrow mesenchymal stem cell-derived exosomal miR-206 promotes osteoblast proliferation and differentiation in osteoarthritis by reducing Elf3.
    Huang Y, Zhang X, Zhan J, Yan Z, Chen D, Xue X, Pan X., Free PMC Article

    02/19/2022
    Circ_0057558 promotes nonalcoholic fatty liver disease by regulating ROCK1/AMPK signaling through targeting miR-206.

    Circ_0057558 promotes nonalcoholic fatty liver disease by regulating ROCK1/AMPK signaling through targeting miR-206.
    Chen X, Tan QQ, Tan XR, Li SJ, Zhang XX., Free PMC Article

    01/29/2022
    GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity.

    GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity.
    Guo S, Gu J, Ma J, Xu R, Wu Q, Meng L, Liu H, Li L, Xu Y., Free PMC Article

    01/29/2022
    MicroRNA-206 antagomiRenriched extracellular vesicles attenuate lung ischemiareperfusion injury through CXCL1 regulation in alveolar epithelial cells.

    MicroRNA-206 antagomiR‒enriched extracellular vesicles attenuate lung ischemia‒reperfusion injury through CXCL1 regulation in alveolar epithelial cells.
    Cai J, Gehrau R, Tu Z, Leroy V, Su G, Shang J, Mas VR, Emtiazjoo A, Pelaez A, Atkinson C, Machuca T, Upchurch GR Jr, Sharma AK., Free PMC Article

    10/2/2021
    miR-206 enforces a slow muscle phenotype.

    miR-206 enforces a slow muscle phenotype.
    Bjorkman KK, Guess MG, Harrison BC, Polmear MM, Peter AK, Leinwand LA., Free PMC Article

    06/26/2021
    miR-206 knockout shows it is critical for myogenesis and directly regulates newly identified target mRNAs.

    miR-206 knockout shows it is critical for myogenesis and directly regulates newly identified target mRNAs.
    Salant GM, Tat KL, Goodrich JA, Kugel JF., Free PMC Article

    05/15/2021
    Palmitic Acid Impairs Myogenesis and Alters Temporal Expression of miR-133a and miR-206 in C2C12 Myoblasts.

    Palmitic Acid Impairs Myogenesis and Alters Temporal Expression of miR-133a and miR-206 in C2C12 Myoblasts.
    da Paixão AO, Bolin AP, Silvestre JG, Rodrigues AC., Free PMC Article

    05/1/2021
    Signaling Modulations of miR-206-3p in Tooth Morphogenesis.

    Signaling Modulations of miR-206-3p in Tooth Morphogenesis.
    Neupane S, Aryal YP, Kim TY, Yeon CY, An CH, Kim JY, Yamamoto H, Lee Y, Sohn WJ, Kim JY., Free PMC Article

    02/20/2021
    miR-206 family is important for mitochondrial and muscle function, but not essential for myogenesis in vitro.

    miR-206 family is important for mitochondrial and muscle function, but not essential for myogenesis in vitro.
    Przanowska RK, Sobierajska E, Su Z, Jensen K, Przanowski P, Nagdas S, Kashatus JA, Kashatus DF, Bhatnagar S, Lukens JR, Dutta A., Free PMC Article

    01/23/2021
    Wnt/beta-catenin signaling induces the myomiRs miR-133b and miR-206 to suppress Pax7 and induce the myogenic differentiation program.

    Wnt/β-catenin signaling induces the myomiRs miR-133b and miR-206 to suppress Pax7 and induce the myogenic differentiation program.
    Cui S, Li L, Mubarokah SN, Meech R.

    08/15/2020
    miR-206 targets Srsf9 to promote C2C12 differentiation.

    miR-1/206 downregulates splicing factor Srsf9 to promote C2C12 differentiation.
    Bjorkman KK, Buvoli M, Pugach EK, Polmear MM, Leinwand LA., Free PMC Article

    08/1/2020
    These results demonstrated that the miR-206-G6PD pathway suppresses muscle cell proliferation, and these findings may facilitate the treatment of muscle diseases.

    MicroRNA-206 regulates cell proliferation by targeting G6PD in skeletal muscle.
    Jiang A, Dong C, Li B, Zhang Z, Chen Y, Ning C, Wu W, Liu H.

    06/27/2020
    This study provides a broad insight into the breast cancer suppressive functions of miR-206.

    A miR-206 regulated gene landscape enhances mammary epithelial differentiation.
    Wang J, Aydoğdu E, Mukhopadhyay S, Helguero LA, Williams C., Free PMC Article

    06/20/2020
    In cardiomyocytes, miR-206 is a upstream regulator of Cx43, and its overexpression downregulates Cx43 to induce abnormal heart-rate and PR interval

    MicroRNA-206 Downregulates Connexin43 in Cardiomyocytes to Induce Cardiac Arrhythmias in a Transgenic Mouse Model.
    Jin Y, Zhou TY, Cao JN, Feng QT, Fu YJ, Xu X, Yang CJ.

    02/29/2020
    miR-206 helped rescue myogenic deficiency by inhibiting CUGBP1 accumulation in cell models of myotonic dystrophy. These data suggest that increased miR-206 levels in myoblasts may lead to better skeletal muscle differentiation.

    Mir-206 partially rescues myogenesis deficiency by inhibiting CUGBP1 accumulation in the cell models of myotonic dystrophy.
    Dong W, Chen X, Wang M, Zheng Z, Zhang X, Xiao Q, Peng X.

    01/18/2020
    acting through histamine 1 receptor, histamine increased miR-206 and miR-216b, which worked in concert to target to Atg13, resulting in the reduction of autophagy activation under hypoxia and acute myocardial infarction condition.

    Histamine deficiency aggravates cardiac injury through miR-206/216b-Atg13 axis-mediated autophagic-dependant apoptosis.
    Ding S, Abudupataer M, Zhou Z, Chen J, Li H, Xu L, Zhang W, Zhang S, Zou Y, Hong T, Wang TC, Yang X, Ge J., Free PMC Article

    11/30/2019
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