| Laminin receptor 1 expression in premalignant and malignant squamous lesions of the cervix. | Laminin receptor 1 expression in premalignant and malignant squamous lesions of the cervix.
Kurdoğlu M, Kurdoğlu Z, Küçükaydın Z, Erten R, Bulut G, Özen S. | 06/25/2024 |
| Ribosomal protein SA is a common component of neuronal intranuclear inclusions in polyglutamine diseases and Marinesco bodies. | Ribosomal protein SA is a common component of neuronal intranuclear inclusions in polyglutamine diseases and Marinesco bodies.
Yagita K, Sadashima S, Koyama S, Noguchi H, Hamasaki H, Sasagasako N, Honda H. | 02/7/2024 |
| LAMR1 restricts Zika virus infection by attenuating the envelope protein ubiquitination. | LAMR1 restricts Zika virus infection by attenuating the envelope protein ubiquitination.
Hu D, Wang Y, Li A, Li Q, Wu C, Shereen MA, Huang S, Wu K, Zhu Y, Wang W, Wu J., Free PMC Article | 01/29/2022 |
| The role of LR-TIMAP/PP1c complex in the occurrence and development of no-reflow. | The role of LR-TIMAP/PP1c complex in the occurrence and development of no-reflow.
Quan X, Liu X, Qin X, Wang Y, Sun T, Li Z, Zhu L, Chen J, Zhou Y, Singh S, Dong H, Zhang Z, Zhang H., Free PMC Article | 11/6/2021 |
| AG-9, an Elastin-Derived Peptide, Increases In Vitro Oral Tongue Carcinoma Cell Invasion, through an Increase in MMP-2 Secretion and MT1-MMP Expression, in a RPSA-Dependent Manner. | AG-9, an Elastin-Derived Peptide, Increases In Vitro Oral Tongue Carcinoma Cell Invasion, through an Increase in MMP-2 Secretion and MT1-MMP Expression, in a RPSA-Dependent Manner.
Bretaudeau C, Baud S, Dupont-Deshorgue A, Cousin R, Brassart B, Brassart-Pasco S., Free PMC Article | 06/26/2021 |
| Mutations in RPSA and NKX2-3 link development of the spleen and intestinal vasculature. | Mutations in RPSA and NKX2-3 link development of the spleen and intestinal vasculature.
Kerkhofs C, Stevens SJC, Faust SN, Rae W, Williams AP, Wurm P, Østern R, Fockens P, Würfel C, Laass M, Kokke F, Stegmann APA, Brunner HG., Free PMC Article | 05/22/2021 |
| MicroRNA-587 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Targeting Ribosomal Protein SA. | MicroRNA-587 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Targeting Ribosomal Protein SA.
Chen M, Wang D, Liu J, Zhou Z, Ding Z, Liu L, Su D, Li H., Free PMC Article | 05/1/2021 |
| Dentate gyrus volume deficit in schizophrenia. | Dentate gyrus volume deficit in schizophrenia.
Nakahara S, Turner JA, Calhoun VD, Lim KO, Mueller B, Bustillo JR, O'Leary DS, McEwen S, Voyvodic J, Belger A, Mathalon DH, Ford JM, Macciardi F, Matsumoto M, Potkin SG, van Erp TGM., Free PMC Article | 04/17/2021 |
| Identification of the Neuroinvasive Pathogen Host Target, LamR, as an Endothelial Receptor for the Treponema pallidum Adhesin Tp0751. | Identification of the Neuroinvasive Pathogen Host Target, LamR, as an Endothelial Receptor for the Treponema pallidum Adhesin Tp0751.
Lithgow KV, Church B, Gomez A, Tsao E, Houston S, Swayne LA, Cameron CE., Free PMC Article | 03/20/2021 |
| LRP::FLAG Rescues Cells from Amyloid-beta-Mediated Cytotoxicity Through Increased TERT Levels and Telomerase Activity. | LRP::FLAG Rescues Cells from Amyloid-β-Mediated Cytotoxicity Through Increased TERT Levels and Telomerase Activity.
Bignoux MJ, Cuttler K, Otgaar TC, Ferreira E, Letsolo BT, Weiss SFT. | 09/19/2020 |
| The development of drugs targeting both ITGA6 and RPSA may be an effective strategy for the treatment of pancreatic cancer. | ITGA6 and RPSA synergistically promote pancreatic cancer invasion and metastasis via PI3K and MAPK signaling pathways.
Wu Y, Tan X, Liu P, Yang Y, Huang Y, Liu X, Meng X, Yu B, Wu M, Jin H. | 05/30/2020 |
| Disease progression-related gradual increment in laminin receptor 1 expression in the epithelial basement membranes of hyperplastic endometrium with or without atypia and cancer of endometrium reveals that it may play a substantial role in the transition from premalignant to the malignant state of endometrial lesions. | Expression of Laminin Receptor 1 in Normal, Hyperplastic, and Malignant Endometrium.
Kurdoglu M, Kucukaydin Z, Kurdoglu Z, Bulut G, Unlu Y, Ozen S. | 11/30/2019 |
| caspase-3 activity assays revealed that apoptosis was induced in both cell lines after siRNA-mediated down-regulation of laminin receptor | siRNA - Mediated LRP/LR knock-down reduces cellular viability of malignant melanoma cells through the activation of apoptotic caspases.
Rebelo TM, Vania L, Ferreira E, Weiss SFT. | 04/6/2019 |
| This review focuses on two particular non-integrin laminin receptors in the epithelial context: dystroglycan and 37/67 laminin receptor (37/67LR).The 37/67LR is a still incompletely understood laminin receptor that is important to regulate intestinal epithelial cell function and could be involved in various pathological conditions. | Non-integrin laminin receptors in epithelia.
Cloutier G, Sallenbach-Morrissette A, Beaulieu JF. | 02/23/2019 |
| Study findings show that the LRP/LR receptor is critically implicated in apoptosis and that LRP/LR down-regulation induces apoptosis in early and late stage colorectal cancer cells through both apoptotic pathways. | Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation.
Vania L, Rebelo TM, Ferreira E, Weiss SFT., Free PMC Article | 01/19/2019 |
| the work revealed that these lysine mutations still appear to be important and can impact the fate and function of 37 LR, by impairing half-life and steady state pre-mRNA levels. These results suggest that the Lys residues within putative SUMO motifs of 37 LR are important for 37 LR function. | Lysines residing in putative Small Ubiquitin-like MOdifier (SUMO) motifs regulate fate and function of 37 KDa laminin receptor.
Umbaugh CS, Figueiredo ML. | 01/12/2019 |
| Mutations in RPSA exons can affect the translated or untranslated regions and can underlie Isolated congenital asplenia with complete or incomplete penetrance. | Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons.
Bolze A, Boisson B, Bosch B, Antipenko A, Bouaziz M, Sackstein P, Chaker-Margot M, Barlogis V, Briggs T, Colino E, Elmore AC, Fischer A, Genel F, Hewlett A, Jedidi M, Kelecic J, Krüger R, Ku CL, Kumararatne D, Lefevre-Utile A, Loughlin S, Mahlaoui N, Markus S, Garcia JM, Nizon M, Oleastro M, Pac M, Picard C, Pollard AJ, Rodriguez-Gallego C, Thomas C, Von Bernuth H, Worth A, Meyts I, Risolino M, Selleri L, Puel A, Klinge S, Abel L, Casanova JL., Free PMC Article | 10/6/2018 |
| The binding of laminin-1 to 67LR causes initial signaling through PKA and Epac, which causes the internalization of 67LR, along with signaling enzymes, such as adenylyl cyclase, into early endosomes. This causes sustained signaling for protection against neuronal cell death induced by serum withdrawal. | Laminin-1 induces endocytosis of 67KDa laminin receptor and protects Neuroscreen-1 cells against death induced by serum withdrawal.
Gopalakrishna R, Gundimeda U, Zhou S, Bui H, Davis A, McNeill T, Mack W. | 01/6/2018 |
| We suggest that PrP(C) and its interactor, LR/37/67 kDa, could be potential therapeutic targets for schwannomas and other Merlin-deficient tumours. | Cellular prion protein (PrP(C)) in the development of Merlin-deficient tumours.
Provenzano L, Ryan Y, Hilton DA, Lyons-Rimmer J, Dave F, Maze EA, Adams CL, Rigby-Jones R, Ammoun S, Hanemann CO. | 11/25/2017 |
| Our results suggest that hypoxia-elicited c-Jun/activator protein 1 regulates 37-kDa laminin receptor precursor expression, which modulates migration and invasion of lung adenocarcinoma cells | 37LRP induces invasion in hypoxic lung adenocarcinoma cancer cells A549 through the JNK/ERK/c-Jun signaling cascade.
Zhou Y, Wang Y, Zhao Z, Wang Y, Zhang N, Zhang H, Liu L. | 07/22/2017 |
| Increased LRP levels correlate with the increased invasive and adhesive potential in early and late stage melanoma cells. | IgG1-iS18 impedes the adhesive and invasive potential of early and late stage malignant melanoma cells.
Munien C, Rebelo TM, Ferreira E, Weiss SF. | 05/20/2017 |
| A polysaccharide from Pinellia ternata inhibits cell proliferation and metastasis in human cholangiocarcinoma cells by targeting of Cdc42 and 67kDa Laminin Receptor | A polysaccharide from Pinellia ternata inhibits cell proliferation and metastasis in human cholangiocarcinoma cells by targeting of Cdc42 and 67kDa Laminin Receptor (LR).
Li Y, Li D, Chen J, Wang S. | 03/18/2017 |
| 67LR plays a considerable role in the development of colon cancer multidrug resistance | Inhibition of human 67-kDa laminin receptor sensitizes multidrug resistance colon cancer cell line SW480 for apoptosis induction.
Lu CL, Xu J, Yao HJ, Luo KL, Li JM, Wu T, Wu GZ. | 02/18/2017 |
| 37LRP regulates the metastasis of glioma cells in vitro and tumor growth in vivo. | The 37-kDa laminin receptor precursor regulates the malignancy of human glioma cells.
Wu H, Li J, Xu D, Jv D, Meng X, Qiao P, Cui T, Shi B. | 01/28/2017 |
| Higher molecular weight Rpsa requires sumoylation to form. | The Transition of the 37-Kda Laminin Receptor (Rpsa) to Higher Molecular Weight Species: Sumoylation or Artifact?
Digiacomo V, Gando IA, Venticinque L, Hurtado A, Meruelo D., Free PMC Article | 08/13/2016 |