| LncRNA MIR100HG Promotes Cell Proliferation in Nasopharyngeal Carcinoma by Targeting miR-136-5p/IL-6 Axis. | LncRNA MIR100HG Promotes Cell Proliferation in Nasopharyngeal Carcinoma by Targeting miR-136-5p/IL-6 Axis.
Huang X, Zhong H, Cai Y. | 05/30/2024 |
| LncRNA MIR100HG affects the proliferation and metastasis of lung cancer cells through mediating the microRNA-5590-3p/DCBLD2 axis. | LncRNA MIR100HG affects the proliferation and metastasis of lung cancer cells through mediating the microRNA-5590-3p/DCBLD2 axis.
Min S, Zhang L, Zhang L, Liu F, Liu M., Free PMC Article | 04/22/2024 |
| A concise review on the role of MIR100HG in human disorders. | A concise review on the role of MIR100HG in human disorders.
Ghafouri-Fard S, Harsij A, Farahzadi H, Hussen BM, Taheri M, Mokhtari M., Free PMC Article | 08/17/2023 |
| Constitutive beta-Catenin Overexpression Represses Lncrna MIR100HG Transcription via HDAC6-Mediated Histone Modification in Colorectal Cancer. | Constitutive β-Catenin Overexpression Represses Lncrna MIR100HG Transcription via HDAC6-Mediated Histone Modification in Colorectal Cancer.
Peng J, Ma Y, Zhao X, Yang X, Wang H. | 06/11/2022 |
| Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m(6)A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression. | Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m(6)A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression.
Liu H, Li D, Sun L, Qin H, Fan A, Meng L, Graves-Deal R, Glass SE, Franklin JL, Liu Q, Wang J, Yeatman TJ, Guo H, Zong H, Jin S, Chen Z, Deng T, Fang Y, Li C, Karijolich J, Patton JG, Wang X, Nie Y, Fan D, Coffey RJ, Zhao X, Lu Y., Free PMC Article | 05/7/2022 |
| The study in vitro suggested down-regulation of MIR100HG expression inhibits cell proliferation, migration, and invasion in gastric cancer. In conclusion, MIR100HG is a credible prognostic biomarker and functions as an oncogenic lncRNA in gastric cancer. | MIR100HG: a credible prognostic biomarker and an oncogenic lncRNA in gastric cancer.
Li J, Xu Q, Wang W, Sun S., Free PMC Article | 04/18/2020 |
| MIR100HG rs1816158 was associated with overall survival in oral cavity cancer. Expression of miR-100 was associated with overall survival in an independent cohort of head and neck squamous cell carcinoma (HNSCC) cases. | MicroRNA-Related Genetic Variants Associated with Survival of Head and Neck Squamous Cell Carcinoma.
Wilkins OM, Titus AJ, Salas LA, Gui J, Eliot M, Butler RA, Sturgis EM, Li G, Kelsey KT, Christensen BC., Free PMC Article | 02/15/2020 |
| MIR100HG formed a triplex structure with p27. Through regulating the expression of p27, MIR100HG promoted cell proliferation in TNBC. Increased expression of MIR100HG was associated with poor prognosis. | LncRNA MIR100HG promotes cell proliferation in triple-negative breast cancer through triplex formation with p27 loci.
Wang S, Ke H, Zhang H, Ma Y, Ao L, Zou L, Yang Q, Zhu H, Nie J, Wu C, Jiao B., Free PMC Article | 12/7/2019 |
| We conclude that MIR100HG potentially serves as a binding platform for both HuR and its target mRNAs, thus modulating HuR-target mRNA interaction | MIR100 host gene-encoded lncRNAs regulate cell cycle by modulating the interaction between HuR and its target mRNAs.
Sun Q, Tripathi V, Yoon JH, Singh DK, Hao Q, Min KW, Davila S, Zealy RW, Li XL, Polycarpou-Schwarz M, Lehrmann E, Zhang Y, Becker KG, Freier SM, Zhu Y, Diederichs S, Prasanth SG, Lal A, Gorospe M, Prasanth KV., Free PMC Article | 06/29/2019 |
| ELK1-induced up-regulation of MIR100HG promoted osteosarcoma progression by epigenetically silencing LATS1 and LATS2. | ELK1-induced upregulation of long non-coding RNA MIR100HG predicts poor prognosis and promotes the progression of osteosarcoma by epigenetically silencing LATS1 and LATS2.
Su X, Teng J, Jin G, Li J, Zhao Z, Cao X, Guo Y, Guo M, Li X, Wu J, Wang C, Guo Z, Guo Q. | 04/6/2019 |
| TGF-beta induces MIR100HG lncRNA, encoding miR-100, let-7a and miR-125b that control pancreatic ductal adenocarcinoma tumorigenesis. Pro-tumorigenic miR-100 and miR-125b increase and anti-tumorigenic let-7a is unchanged, as TGF-beta also induces LIN28B. The induction of LIN28B results in the up-regulation of miR-100 and miR-125b, with let-7a unchanged despite being part of the same MIR100HG primary transcript. | TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression.
Ottaviani S, Stebbing J, Frampton AE, Zagorac S, Krell J, de Giorgio A, Trabulo SM, Nguyen VTM, Magnani L, Feng H, Giovannetti E, Funel N, Gress TM, Jiao LR, Lombardo Y, Lemoine NR, Heeschen C, Castellano L., Free PMC Article | 12/22/2018 |
| Linc-NeD125 represents the host gene for miR-125b-1, a microRNA with an established role as negative regulator of human neuroblastoma cell proliferation. | Identification of linc-NeD125, a novel long non coding RNA that hosts miR-125b-1 and negatively controls proliferation of human neuroblastoma cells.
Bevilacqua V, Gioia U, Di Carlo V, Tortorelli AF, Colombo T, Bozzoni I, Laneve P, Caffarelli E., Free PMC Article | 10/22/2016 |
| This study reveals an unprecedented function of long non-coding RNAs MONC and MIR100HG as regulators of hematopoiesis and oncogenes in the development of myeloid leukemia. | LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia.
Emmrich S, Streltsov A, Schmidt F, Thangapandi VR, Reinhardt D, Klusmann JH., Free PMC Article | 07/4/2015 |
| Tag single nucleotide polymorphisms near the BLID and LOC399959 genes are not susceptibility loci for high myopia in the Chinese Han population. | Evaluation of BLID and LOC399959 as candidate genes for high myopia in the Chinese Han population.
Zhao F, Bai J, Chen W, Xue A, Li C, Yan Z, Chen H, Lu F, Hu Y, Qu J, Zeng C, Zhou X, Zhao F, Bai J, Chen W, Xue A, Li C, Yan Z, Chen H, Lu F, Hu Y, Qu J, Zeng C, Zhou X., Free PMC Articles: PMC2956664, PMC2956664 | 02/26/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | Evaluation of BLID and LOC399959 as candidate genes for high myopia in the Chinese Han population.
Zhao F, Bai J, Chen W, Xue A, Li C, Yan Z, Chen H, Lu F, Hu Y, Qu J, Zeng C, Zhou X, Zhao F, Bai J, Chen W, Xue A, Li C, Yan Z, Chen H, Lu F, Hu Y, Qu J, Zeng C, Zhou X., Free PMC Articles: PMC2956664, PMC2956664 | 12/5/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.
Nakanishi H, Yamada R, Gotoh N, Hayashi H, Yamashiro K, Shimada N, Ohno-Matsui K, Mochizuki M, Saito M, Iida T, Matsuo K, Tajima K, Yoshimura N, Matsuda F., Free PMC Article | 12/2/2009 |