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    fng fringe [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40314, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila.

    Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila.
    Pandey A, Harvey BM, Lopez MF, Ito A, Haltiwanger RS, Jafar-Nejad H., Free PMC Article

    09/19/2020
    Mapping Sites of O-Glycosylation and Fringe Elongation on Drosophila Notch.

    Mapping Sites of O-Glycosylation and Fringe Elongation on Drosophila Notch.
    Harvey BM, Rana NA, Moss H, Leonardi J, Jafar-Nejad H, Haltiwanger RS., Free PMC Article

    05/13/2017
    The function of Chi and dLMO on Notch signaling is dependent on the regulation of fng transcription.

    Chi and dLMO function antagonistically on Notch signaling through directly regulation of fng transcription.
    Han H, Fan J, Xiong Y, Wu W, Lu Y, Zhang L, Zhao Y., Free PMC Article

    12/17/2016
    Fringe modulated Notch-ligand cis interactions during Drosophila development.

    Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states.
    LeBon L, Lee TV, Sprinzak D, Jafar-Nejad H, Elowitz MB., Free PMC Article

    07/4/2015
    FOXO-mediated regulation of fringe links the insulin and Notch signaling pathways in the germline stem cell niche.

    FOXO/Fringe is necessary for maintenance of the germline stem cell niche in response to insulin insufficiency.
    Yang SA, Wang WD, Chen CT, Tseng CY, Chen YN, Hsu HJ.

    11/30/2013
    Eaat1 expression is promoted by Fringe-mediated neuron-glial communication during development and suggest that Eaat1 plays an essential role in regulating central nervous system neural circuits that control locomotion in Drosophila

    Drosophila glial glutamate transporter Eaat1 is regulated by fringe-mediated notch signaling and is essential for larval locomotion.
    Stacey SM, Muraro NI, Peco E, Labbé A, Thomas GB, Baines RA, van Meyel DJ., Free PMC Article

    12/4/2010
    the addition of N-acetylglucosamine is the basis for the effects of Fringe on Drosophila Notch-ligand binding

    In vitro reconstitution of the modulation of Drosophila Notch-ligand binding by Fringe.
    Xu A, Haines N, Dlugosz M, Rana NA, Takeuchi H, Haltiwanger RS, Irvine KD.

    01/21/2010
    suppresses effects of OFUT1 on Notch binding; decreases Serrate-Notch binding but increases Delta-Notch binding.

    Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe.
    Okajima T, Xu A, Irvine KD.

    01/21/2010
    analysis of Drosophila Notch regions that contribute to ligand binding and the modulatory influence of Fringe

    Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe.
    Xu A, Lei L, Irvine KD.

    01/21/2010
    molecular genetic analysis

    Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila.
    Correia T, Papayannopoulos V, Panin V, Woronoff P, Jiang J, Vogt TF, Irvine KD., Free PMC Article

    01/21/2010
    Myosin II (zipper) and fringe have roles in planar polarization of the denticle field in the Drosophila embryo

    Planar polarization of the denticle field in the Drosophila embryo: roles for Myosin II (zipper) and fringe.
    Walters JW, Dilks SA, DiNardo S., Free PMC Article

    01/21/2010
    Fringe is required in the stretched cells and the anterior main body follicular cells to control stretched cell number and the timing of main body follicular cell displacement.

    Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis.
    Grammont M., Free PMC Article

    01/21/2010
    modulation of Notch signaling by Fng is important for central nervous system development

    The glycosyltransferase Fringe promotes Delta-Notch signaling between neurons and glia, and is required for subtype-specific glial gene expression.
    Thomas GB, van Meyel DJ.

    01/21/2010
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