The inhibition of YTHDF3/m[6]A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer. | The inhibition of YTHDF3/m(6)A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer. Zhong S, Guo Q, Chen X, Luo X, Long Y, Chong T, Ye M, He H, Lu A, Ao K, Yin M, Xu A, Li X, Hao Y, Guo X., Free PMC Article | 02/16/2024 |
LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women. | LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women. Li J, Liu Z, Ren Y, Shao H, Li S., Free PMC Article | 05/23/2023 |
Overexpression of circRNAs LRP6 in gestational diabetes mellitus predicts foetal malformation and intrauterine death. | Overexpression of circRNAs LRP6 in gestational diabetes mellitus predicts foetal malformation and intrauterine death. Hao H, Liu Q, Chen J, Zhou H. | 03/22/2023 |
LRP6/filamentous-actin signaling facilitates osteogenic commitment in mechanically induced periodontal ligament stem cells. | LRP6/filamentous-actin signaling facilitates osteogenic commitment in mechanically induced periodontal ligament stem cells. Wang J, Yang H, Ma X, Liu J, Li L, Chen L, Wei F., Free PMC Article | 02/4/2023 |
A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer's disease. | A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer's disease. Jones ME, Büchler J, Dufor T, Palomer E, Teo S, Martin-Flores N, Boroviak K, Metzakopian E, Gibb A, Salinas PC., Free PMC Article | 01/21/2023 |
An LRP6 mutation (Arg360His) associated with low bone mineral density but not cardiovascular events in a Caucasian family. | An LRP6 mutation (Arg360His) associated with low bone mineral density but not cardiovascular events in a Caucasian family. Puente N, Vega AI, Hernandez JL, Fernandez-Luna JL, Riancho JA., Free PMC Article | 10/22/2022 |
Mutations in LRP6 highlight the role of WNT signaling in oral exostoses and dental anomalies. | Mutations in LRP6 highlight the role of WNT signaling in oral exostoses and dental anomalies. Kantaputra P, Jatooratthawichot P, Chintakanon K, Intachai W, Pradermdutsadeeporn P, Adisornkanj P, Tongsima S, Ngamphiw C, Olsen B, Tucker AS, Ketudat Cairns JR. | 09/24/2022 |
Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy. | Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy. Li S, Yang M, He Y, Jiang X, Zhao R, Liu W, Huang L, Shi Y, Li X, Sun K, Yang Y, Sundaresan P, Zhao P, Yang Z, Zhu X. | 09/3/2022 |
SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/beta-catenin signaling. | SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling. Rong Z, Zhang L, Li Z, Xiao Z, Duan Y, Ren X, Zi Y, Gao J, Mu Y, Guan Y, Cao Z, Wang X, Pei Q, Zeng Y, Fan Q, Zeng Z, Ou D, He J, Nie Y, Tan R, Weng L, Li Y, Xiang R, Deng Y, Sun L. | 05/7/2022 |
circLRP6 contributes to osteosarcoma progression by regulating the miR1413p/HDAC4/HMGB1 axis. | circ‑LRP6 contributes to osteosarcoma progression by regulating the miR‑141‑3p/HDAC4/HMGB1 axis. Yu Y, Dong G, Li Z, Zheng Y, Shi Z, Wang G., Free PMC Article | 03/26/2022 |
Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/beta-catenin-Cyp2e1 Signaling. | Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-Cyp2e1 Signaling. Chen LJ, Lin XX, Guo J, Xu Y, Zhang SX, Chen D, Zhao Q, Xiao J, Lian GH, Peng SF, Guo D, Yang H, Shu Y, Zhou HH, Zhang W, Chen Y., Free PMC Article | 02/19/2022 |
Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer. | Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer. Zhu H, Su Z, Ning J, Zhou L, Tan L, Sayed S, Song J, Wang Z, Li H, Sun Q, Liu S, Sha O, Leng F, Chen X, Lu D., Free PMC Article | 02/5/2022 |
The complex role of Wnt ligands in type 2 diabetes mellitus and related complications. | The complex role of Wnt ligands in type 2 diabetes mellitus and related complications. Nie X, Wei X, Ma H, Fan L, Chen WD., Free PMC Article | 02/5/2022 |
PUM1 modulates trophoblast cell proliferation and migration through LRP6. | PUM1 modulates trophoblast cell proliferation and migration through LRP6. Wang Y, Sun L, Wang L, Yu H, Yu X, Zou Y. | 01/22/2022 |
MicroRNA-513c-5p is involved in the pathogenesis of preeclampsia by regulating of low-density lipoprotein receptor-associated protein 6. | MicroRNA-513c-5p is involved in the pathogenesis of preeclampsia by regulating of low-density lipoprotein receptor-associated protein 6. Zhou Q, Li H, Zhang Y, Peng W, Hou H, Gu M, Zhang F, Wang X, Gu X, Li L., Free PMC Article | 01/15/2022 |
Low-Density Lipoprotein Receptor-Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes. | Low-Density Lipoprotein Receptor-Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes. Chow HM, Sun JK, Hart RP, Cheng KK, Hung CHL, Lau TM, Kwan KM., Free PMC Article | 12/25/2021 |
Unveiling the Roles of Low-Density Lipoprotein Receptor-Related Protein 6 in Intestinal Homeostasis, Regeneration and Oncogenesis. | Unveiling the Roles of Low-Density Lipoprotein Receptor-Related Protein 6 in Intestinal Homeostasis, Regeneration and Oncogenesis. Raisch J, Côté-Biron A, Langlois MJ, Leblanc C, Rivard N., Free PMC Article | 10/30/2021 |
Clinical Phenotype and Relevance of LRP5 and LRP6 Variants in Patients With Early-Onset Osteoporosis (EOOP). | Clinical Phenotype and Relevance of LRP5 and LRP6 Variants in Patients With Early-Onset Osteoporosis (EOOP). Stürznickel J, Rolvien T, Delsmann A, Butscheidt S, Barvencik F, Mundlos S, Schinke T, Kornak U, Amling M, Oheim R. | 09/18/2021 |
Hsa_circ_0099198 facilitates the progression of retinoblastoma by regulating miR-1287/LRP6 axis. | Hsa_circ_0099198 facilitates the progression of retinoblastoma by regulating miR-1287/LRP6 axis. Jiang Y, Xiao F, Wang L, Wang T, Chen L. | 09/18/2021 |
Circ-LRP6 mediates epithelial-mesenchymal transition and autophagy in oral squamous cell carcinomas. | Circ-LRP6 mediates epithelial-mesenchymal transition and autophagy in oral squamous cell carcinomas. Zhang Q, Jiang C, Ren W, Li S, Zheng J, Gao Y, Zhi K, Gao L. | 09/18/2021 |
The rs2302685 polymorphism in the LRP6 gene is associated with bone mineral density and body composition in Iranian children. | The rs2302685 polymorphism in the LRP6 gene is associated with bone mineral density and body composition in Iranian children. Montazeri-Najafabady N, Dabbaghmanesh MH, Mohammadian Amiri R. | 09/4/2021 |
MiR-30a suppresses clear cell renal cell carcinoma proliferation and metastasis by targeting LRP6. | MiR-30a suppresses clear cell renal cell carcinoma proliferation and metastasis by targeting LRP6. Ren Y, Zhang L, Zhang W, Gao Y. | 08/7/2021 |
Low-density lipoprotein receptor-related protein 6 regulates cardiomyocyte-derived paracrine signaling to ameliorate cardiac fibrosis. | Low-density lipoprotein receptor-related protein 6 regulates cardiomyocyte-derived paracrine signaling to ameliorate cardiac fibrosis. Wang X, Zou Y, Chen Z, Li Y, Pan L, Wang Y, Liu M, Yin C, Wu J, Yang C, Zhang L, Li C, Huang Z, Wang D, Qian J, Ge J, Zou Y, Gong H., Free PMC Article | 07/24/2021 |
ERK1/2 inhibition reduces vascular calcification by activating miR-126-3p-DKK1/LRP6 pathway. | ERK1/2 inhibition reduces vascular calcification by activating miR-126-3p-DKK1/LRP6 pathway. Zeng P, Yang J, Liu L, Yang X, Yao Z, Ma C, Zhu H, Su J, Zhao Q, Feng K, Yang S, Zhu Y, Li X, Wang W, Duan Y, Han J, Chen Y., Free PMC Article | 07/24/2021 |
MicroRNA590 inhibits migration, invasion and epithelialtomesenchymal transition of esophageal squamous cell carcinoma by targeting lowdensity lipoprotein receptorrelated protein 6. | MicroRNA‑590 inhibits migration, invasion and epithelial‑to‑mesenchymal transition of esophageal squamous cell carcinoma by targeting low‑density lipoprotein receptor‑related protein 6. Guan H, Liu J, Lv P, Zhou L, Zhang J, Cao W., Free PMC Article | 07/10/2021 |