| Integrative high-throughput enhancer surveying and functional verification divulges a YY2-condensed regulatory axis conferring risk for osteoporosis. | Integrative high-throughput enhancer surveying and functional verification divulges a YY2-condensed regulatory axis conferring risk for osteoporosis.
Chen XF, Duan YY, Jia YY, Dong QH, Shi W, Zhang Y, Dong SS, Li M, Liu Z, Chen F, Huang XT, Hao RH, Zhu DL, Jing RH, Guo Y, Yang TL., Free PMC Article | 03/19/2024 |
| YY2-DRP1 Axis Regulates Mitochondrial Fission and Determines Cancer Stem Cell Asymmetric Division. | YY2-DRP1 Axis Regulates Mitochondrial Fission and Determines Cancer Stem Cell Asymmetric Division.
Wei M, Nurjanah U, Li J, Luo X, Hosea R, Li Y, Zeng J, Duan W, Song G, Miyagishi M, Kasim V, Wu S., Free PMC Article | 08/22/2023 |
| Homeostasis Imbalance of YY2 and YY1 Promotes Tumor Growth by Manipulating Ferroptosis. | Homeostasis Imbalance of YY2 and YY1 Promotes Tumor Growth by Manipulating Ferroptosis.
Li Y, Li J, Li Z, Wei M, Zhao H, Miyagishi M, Wu S, Kasim V., Free PMC Article | 05/14/2022 |
| Biological roles of Yin Yang 2: Its implications in physiological and pathological events. | Biological roles of Yin Yang 2: Its implications in physiological and pathological events.
Li L, Li Y, Timothy Sembiring Meliala I, Kasim V, Wu S., Free PMC Article | 06/19/2021 |
| different effects of YY1 and YY2 on gene expression patterns | The transcription factor YY2 has less momentous properties of an intrinsically disordered protein than its paralog YY1.
Figiel M, Łakomska J, Miłek P, Dziedzicka-Wasylewska M, Górecki A. | 06/20/2020 |
| A summary is of the published studies on the expression levels of YY1 in human cancers and their potential cross-reactivities with YY2 is also provided. Well-documented monospecific antibodies to both YY1 and YY2 have to be developed and used when examining the expression levels of YY1 and YY2 in human cancers to elucidate the accurate relationship between them and clinical significance of each. | The Forgotten YY2 in Reported YY1 Expression Levels in Human Cancers.
Kaufhold S, Aziz N, Bonavida B. | 04/6/2019 |
| In human colorectal cancer metastases to the liver, the levels of AES protein are correlated with those of YY2 | Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2.
Kakizaki F, Sonoshita M, Miyoshi H, Itatani Y, Ito S, Kawada K, Sakai Y, Taketo MM., Free PMC Article | 02/18/2017 |
| article summarizes all critical aspects that are (or will be) relevant for a better understanding of YY1- and/or YY2-mediated cellular control mechanisms | Yin Yang 2: the great unknown within the Yin Yang 1 regulatory network.
Klar M. | 03/24/2012 |
| Results show that human YY2 is not redundant to YY1, and YY2 is a significant regulator of genes previously identified as uniquely responding to YY1. | Genome-wide analysis of YY2 versus YY1 target genes.
Chen L, Shioda T, Coser KR, Lynch MC, Yang C, Schmidt EV., Free PMC Article | 08/2/2010 |
| yy2 expression is mediated by its own methylation-sensitive promoter. | Transcriptional activity of the novel identified human yy2 promoter is modified by DNA methylation.
Klar M, Drews D, Dame C. | 01/21/2010 |
| the novel factor YY2 antagonizes the negative actions exerted by YY1 | Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2.
Klar M, Bode J., Free PMC Article | 01/21/2010 |
| YY2 can bind to and regulate some promoters known to be controlled by YY1. Similar to YY1, YY2 contains both transcriptional activation and repression functions. | Molecular cloning and functional characterization of the transcription factor YY2.
Nguyen N, Zhang X, Olashaw N, Seto E. | 01/21/2010 |