| Myoglobin in Brown Adipose Tissue: A Multifaceted Player in Thermogenesis. | Myoglobin in Brown Adipose Tissue: A Multifaceted Player in Thermogenesis.
Aboouf MA, Gorr TA, Hamdy NM, Gassmann M, Thiersch M., Free PMC Article | 09/29/2023 |
| Comparative analysis of the myoglobin gene in whales and humans reveals evolutionary changes in regulatory elements and expression levels. | Comparative analysis of the myoglobin gene in whales and humans reveals evolutionary changes in regulatory elements and expression levels.
Sackerson C, Garcia V, Medina N, Maldonado J, Daly J, Cartwright R., Free PMC Article | 09/6/2023 |
| Pseudoperoxidase activity, conformational stability, and aggregation propensity of the His98Tyr myoglobin variant: implications for the onset of myoglobinopathy. | Pseudoperoxidase activity, conformational stability, and aggregation propensity of the His98Tyr myoglobin variant: implications for the onset of myoglobinopathy.
Hofbauer S, Pignataro M, Borsari M, Bortolotti CA, Di Rocco G, Ravenscroft G, Furtmüller PG, Obinger C, Sola M, Battistuzzi G., Free PMC Article | 05/21/2022 |
| Myoglobin Protects Breast Cancer Cells Due to Its ROS and NO Scavenging Properties. | Myoglobin Protects Breast Cancer Cells Due to Its ROS and NO Scavenging Properties.
Quinting T, Heymann AK, Bicker A, Nauth T, Bernardini A, Hankeln T, Fandrey J, Schreiber T., Free PMC Article | 02/19/2022 |
| GAPDH is involved in the heme-maturation of myoglobin and hemoglobin. | GAPDH is involved in the heme-maturation of myoglobin and hemoglobin.
Tupta B, Stuehr E, Sumi MP, Sweeny EA, Smith B, Stuehr DJ, Ghosh A., Free PMC Article | 01/15/2022 |
| Protective Potential of Uric Acid, Folic Acid, Glutathione and Ascorbic Acid Against the Formation of Toxic Met-Myoglobin. | Protective Potential of Uric Acid, Folic Acid, Glutathione and Ascorbic Acid Against the Formation of Toxic Met-Myoglobin.
Al Abdulmonem W, Aljohani ASM, Alhumaydhi FA, Mousa AHM, Rasheed Z. | 07/3/2021 |
| Molecular Dynamics Simulation and Kinetic Study of Fluoride Binding to V21C/V66C Myoglobin with a Cytoglobin-like Disulfide Bond. | Molecular Dynamics Simulation and Kinetic Study of Fluoride Binding to V21C/V66C Myoglobin with a Cytoglobin-like Disulfide Bond.
Yin LL, Xu JK, Wang XJ, Gao SQ, Lin YW., Free PMC Article | 01/16/2021 |
| Myoglobin for Detection of High-Risk Patients with Acute Myocarditis. | Myoglobin for Detection of High-Risk Patients with Acute Myocarditis.
Kottwitz J, Bruno KA, Berg J, Salomon GR, Fairweather D, Elhassan M, Baltensperger N, Kissel CK, Lovrinovic M, Baltensweiler A, Schmied C, Templin C, Lima JAC, Landmesser U, Lüscher TF, Manka R, Heidecker B., Free PMC Article | 12/12/2020 |
| The role of myoglobin in epithelial cancers: Insights from transcriptomics. | The role of myoglobin in epithelial cancers: Insights from transcriptomics.
Bicker A, Nauth T, Gerst D, Aboouf MA, Fandrey J, Kristiansen G, Gorr TA, Hankeln T., Free PMC Article | 09/12/2020 |
| Despite the structural similarity of myoglobin to alpha and beta subunits of hemoglobin, there is a functional difference between the two proteins, owing to the quaternary structure of hemoglobin. The effect of the quaternary structure of hemoglobin on the intrinsic dynamics of its subunits is explored by dynamical comparison of the two proteins. | Dynamical comparison between myoglobin and hemoglobin.
Aharoni R, Tobi D. | 08/31/2019 |
| Study identifies a recurrent c.292C>T (p.His98Tyr) substitution in MB in fourteen members of six European families suffering from an autosomal dominant progressive myopathy with highly characteristic sarcoplasmic inclusions in skeletal and cardiac muscle. Myoglobinopathy manifests in adulthood with proximal and axial weakness that progresses to involve distal muscles and causes respiratory and cardiac failure. | Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions.
Olivé M, Engvall M, Ravenscroft G, Cabrera-Serrano M, Jiao H, Bortolotti CA, Pignataro M, Lambrughi M, Jiang H, Forrest ARR, Benseny-Cases N, Hofbauer S, Obinger C, Battistuzzi G, Bellei M, Borsari M, Di Rocco G, Viola HM, Hool LC, Cladera J, Lagerstedt-Robinson K, Xiang F, Wredenberg A, Miralles F, Baiges JJ, Malfatti E, Romero NB, Streichenberger N, Vial C, Claeys KG, Straathof CSM, Goris A, Freyer C, Lammens M, Bassez G, Kere J, Clemente P, Sejersen T, Udd B, Vidal N, Ferrer I, Edström L, Wedell A, Laing NG., Free PMC Article | 04/27/2019 |
| The results showed that the MI-based bio-sensing system had high selectivity and sensitivity for detection of Cardiac biomarkers . Compared with the control region, ultrasensitive detections of CRP and Mb were accomplished with the detection limits of 1.0 pg/mL and 0.1 pg/mL, respectively. | A Multi-Region Magnetoimpedance-Based Bio-Analytical System for Ultrasensitive Simultaneous Determination of Cardiac Biomarkers Myoglobin and C-Reactive Protein.
Yang Z, Wang H, Guo P, Ding Y, Lei C, Luo Y., Free PMC Article | 10/6/2018 |
| Report morphology of myoglobin casts in renal biopsies with acute kidney injury. | Myoglobin casts in renal biopsies: immunohistochemistry and morphologic spectrum.
Liapis H, Boils C, Hennigar R, Silva F. | 08/19/2017 |
| Myoglobin is associated with larger hematoma volume and growth after adjusting potential confounding factors in intracerebral hemorrhage. | High Level of Serum Myoglobin in Human Intracerebral Hemorrhage: Implications for Large Hematoma Volume and Growth.
Xu M, Lin J, Lei C, Liu J, Yuan R, Tan G, Liu M. | 05/6/2017 |
| we found that the A79G polymorphism of the MB gene plays an important role in influencing the development of exercise-induced skeletal muscle damage. | Myoglobin A79G polymorphism association with exercise-induced skeletal muscle damage.
Cui T, Jiang MS. | 02/18/2017 |
| Electroanalysis of myoglobin as a marker of acute myocardial infarction by means of screenprinted electrodes modified with multiwalled carbon nanotubes and polymeric artificial antibodies is developed. Plastic antibodies to myoglobin (molecularly imprinted polymers, MIPs) based on o-phenylenediamine were produced by electropolymerization. Molecular imprinting technology in biosensor analysis was used. | Electroanalysis of myoglobin based on electropolymerized molecularly imprinted polymer poly-o-phenylenediamine and carbon nanotubes/screen printed electrode.
Shumyantseva VV, Bulko TV, Sigolaeva LV, Kuzikov AV, Archakov AI. | 01/28/2017 |
| In the absence of Mb, the Y-shape structure remains intact. So, a weak electrochemical signal is observed. Upon addition of target, the DApt leave the CS and bind to Mb, leading to disassembly of Y-shape structure and following the addition of Exo I, a strong electrochemical signal could be recorded. | A novel electrochemical aptasensor based on Y-shape structure of dual-aptamer-complementary strand conjugate for ultrasensitive detection of myoglobin.
Taghdisi SM, Danesh NM, Ramezani M, Emrani AS, Abnous K. | 11/19/2016 |
| analysis of myoglobin gene regulatory networks in breast and prostate cancer | The Distinct Gene Regulatory Network of Myoglobin in Prostate and Breast Cancer.
Bicker A, Brahmer AM, Meller S, Kristiansen G, Gorr TA, Hankeln T., Free PMC Article | 07/2/2016 |
| Data show that with the myoglobin (MYO) monoclonal antibody of high specificity and affinity, a one-step sandwich ELISA for detecting MYO has been established successfully, which provides a basis for the development of domestic ELISA kit. | [Preparation and application of monoclonal antibody against human myoglobin].
Yang Q, Liu S, Tan S, Shao C, Huang J, Xiang J. | 12/19/2015 |
| Misfolding and amyloid aggregation of apomyoglobin. | Misfolding and amyloid aggregation of apomyoglobin.
Iannuzzi C, Maritato R, Irace G, Sirangelo I., Free PMC Article | 10/17/2015 |
| A non-ischemic serum myoglobin release is rare, but could be associated in subgroups of patients. | Associated factors for non-ischemic serum myoglobin release after cardiac surgical procedures.
Arndt-H K, Florian G, A SU, Andres BF, Angela K, Anton M. | 04/18/2015 |
| Data show that chimeric neuroglobin and myoglobin were generated by swapping a regulatory segment. | Engineered chimeras reveal the structural basis of hexacoordination in globins: a case study of neuroglobin and myoglobin.
Boron I, Capece L, Pennacchietti F, Wetzler DE, Bruno S, Abbruzzetti S, Chisari L, Luque FJ, Viappiani C, Marti MA, Estrin DA, Nadra AD. | 02/21/2015 |
| Findings indicate that myoglobin (Mb) and neuroglobin (Ngb) can be expressed in nonmuscle and non-neural contexts. | Hematopoietic stem/progenitor cells express myoglobin and neuroglobin: adaptation to hypoxia or prevention from oxidative stress?
D'Aprile A, Scrima R, Quarato G, Tataranni T, Falzetti F, Di Ianni M, Gemei M, Del Vecchio L, Piccoli C, Capitanio N. | 12/20/2014 |
| Analogous to breast cancer, MB expression in prostate cancer is associated with steroid hormone signaling and markers of hypoxia | Myoglobin expression in prostate cancer is correlated to androgen receptor expression and markers of tumor hypoxia.
Meller S, Bicker A, Montani M, Ikenberg K, Rostamzadeh B, Sailer V, Wild P, Dietrich D, Uhl B, Sulser T, Moch H, Gorr TA, Stephan C, Jung K, Hankeln T, Kristiansen G. | 11/29/2014 |
| the novel cancer-associated MB splice variants exhibited increased expression in tumor cells subjected to experimental hypoxia; the novel gene regulatory mechanisms unveiled in this study support the idea of a non-canonical role of MB during carcinogenesis | Extensive transcriptional complexity during hypoxia-regulated expression of the myoglobin gene in cancer.
Bicker A, Dietrich D, Gleixner E, Kristiansen G, Gorr TA, Hankeln T. | 08/9/2014 |