| Melanocortin-4 Receptor PLC Activation Is Modulated by an Interaction with the Monocarboxylate Transporter 8. | Melanocortin-4 Receptor PLC Activation Is Modulated by an Interaction with the Monocarboxylate Transporter 8.
Anthofer L, Gmach P, Uretmen Kagiali ZC, Kleinau G, Rotter J, Opitz R, Scheerer P, Beck-Sickinger AG, Wolf P, Biebermann H, Bechmann I, Kühnen P, Krude H, Paisdzior S., Free PMC Article | 09/5/2024 |
| The Association between Obesity Susceptibility and Polymorphisms of MC4R, SH2B1, and NEGR1 in Tibetans. | The Association between Obesity Susceptibility and Polymorphisms of MC4R, SH2B1, and NEGR1 in Tibetans.
Huang T, Zhang X, Li Q, Li X, Yao J, Song J, Chen Y, Ye L, Li C, Xiran P, Wen Y. | 08/15/2024 |
| Novel Melanocortin-3 and -4 Receptor Functional Variants in Asian Children With Severe Obesity. | Novel Melanocortin-3 and -4 Receptor Functional Variants in Asian Children With Severe Obesity.
Ong SG, Dehghan R, Dorajoo R, Liu JJ, Sng AA, Lee YS, Ooi DSQ. | 07/1/2024 |
| Unexpected identification of obesity-associated mutations in LEP and MC4R genes in patients with anorexia nervosa. | Unexpected identification of obesity-associated mutations in LEP and MC4R genes in patients with anorexia nervosa.
Rajcsanyi LS, Zheng Y, Herpertz-Dahlmann B, Seitz J, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Giel K, Egberts K, Burghardt R, Föcker M, Antel J, Fischer-Posovszky P, Hebebrand J, Hinney A., Free PMC Article | 04/5/2024 |
| Evaluation of the role of FTO (rs9939609) and MC4R (rs17782313) gene polymorphisms in type 1 diabetes and their relation to obesity. | Evaluation of the role of FTO (rs9939609) and MC4R (rs17782313) gene polymorphisms in type 1 diabetes and their relation to obesity.
Mosaad YM, Morzak M, Abd El Aziz El Chennawi F, Elsharkawy AA, Abdelsalam M. | 02/14/2024 |
| Predisposition of the Common MC4R rs17782313 Female Carriers to Elevated Obesity and Interaction with Eating Habits. | Predisposition of the Common MC4R rs17782313 Female Carriers to Elevated Obesity and Interaction with Eating Habits.
Chermon D, Birk R., Free PMC Article | 11/28/2023 |
| Functional Characterization of Novel MC4R Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar. | Functional Characterization of Novel MC4R Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar.
Mohammed I, Selvaraj S, Ahmed WS, Al-Barazenji T, Hammad AS, Dauleh H, Saraiva LR, Al-Shafai M, Hussain K., Free PMC Article | 11/28/2023 |
| Computational analysis of missense variants of human MC4R and childhood obesity. | Computational analysis of missense variants of human MC4R and childhood obesity.
Douiyeh I, Khamlich J, Saih A, Baggar A, Kettani A, Safi A. | 11/14/2023 |
| Influence of polymorphisms in IRS1, IRS2, MC3R, and MC4R on metabolic and inflammatory status and food intake in Brazilian adults: An exploratory pilot study. | Influence of polymorphisms in IRS1, IRS2, MC3R, and MC4R on metabolic and inflammatory status and food intake in Brazilian adults: An exploratory pilot study.
Fajardo CM, Cerda A, Bortolin RH, de Oliveira R, Stefani TIM, Dos Santos MA, Braga AA, Dorea EL, Bernik MMS, Bastos GM, Sampaio MF, Damasceno NRT, Verlengia R, de Oliveira MRM, Hirata MH, Hirata RDC. | 11/14/2023 |
| Functional Characterization of MC4R Variants in Chinese Morbid Obese Patients and Weight Loss after Bariatric Surgery. | Functional Characterization of MC4R Variants in Chinese Morbid Obese Patients and Weight Loss after Bariatric Surgery.
Gong Y, Wu Q, Huang S, Fu Z, Ye J, Liu R, Lin S, Guan W, Yang N, Li JZ, Liang H, Zhou H. | 09/27/2023 |
| Sex differences in weight gain, blood pressure control, and responses to melanocortin-4 receptor antagonism in offspring from lean and obese parents. | Sex differences in weight gain, blood pressure control, and responses to melanocortin-4 receptor antagonism in offspring from lean and obese parents.
do Carmo JM, Dai X, Aitken N, Larson KM, Omoto ACM, Gulke RR, Wang Z, Li X, Mouton AJ, Hall JE, da Silva AA., Free PMC Article | 09/13/2023 |
| The rs17782313 polymorphism near MC4R gene confers a high risk of obesity and hyperglycemia, while PGC1alpha rs8192678 polymorphism is weakly correlated with glucometabolic disorder: a systematic review and meta-analysis. | The rs17782313 polymorphism near MC4R gene confers a high risk of obesity and hyperglycemia, while PGC1α rs8192678 polymorphism is weakly correlated with glucometabolic disorder: a systematic review and meta-analysis.
Zhang Y, Li S, Nie H, Wang X, Li X, Wen J, Li M, Song Y., Free PMC Article | 09/7/2023 |
| Investigation the interaction of dietary fat quality indices and the MC4R gene in metabolically healthy and unhealthy overweight and obese women. | Investigation the interaction of dietary fat quality indices and the MC4R gene in metabolically healthy and unhealthy overweight and obese women.
Rasaei N, Fallah M, Nemati M, Gholami F, Ghaffarian-Ensaf R, Mirzaei K., Free PMC Article | 08/2/2023 |
| The interaction between MC4R gene variant (rs17782313) and dominant dietary patterns on depression in obese and overweight women: a cross sectional study. | The interaction between MC4R gene variant (rs17782313) and dominant dietary patterns on depression in obese and overweight women: a cross sectional study.
Hajmir MM, Mirzababaei A, Clark CCT, Ghaffarian-Ensaf R, Mirzaei K., Free PMC Article | 05/19/2023 |
| Genetic association of the rs17782313 polymorphism with antipsychotic-induced weight gain. | Genetic association of the rs17782313 polymorphism with antipsychotic-induced weight gain.
Schreyer KF, Leucht S, Heres S, Steimer W., Free PMC Article | 03/15/2023 |
| The interaction between dietary approaches to stop hypertension and MC4R gene variant in predicting cardiovascular risk factors. | The interaction between dietary approaches to stop hypertension and MC4R gene variant in predicting cardiovascular risk factors.
Yarizadeh H, Bahiraee A, Asadi S, Maddahi NS, Setayesh L, Casazza K, Mirzaei K. | 01/14/2023 |
| Effect of the Melanocortin 4-Receptor Ile269Asn Mutation on Weight Loss Response to Dietary, Phentermine and Bariatric Surgery Interventions. | Effect of the Melanocortin 4-Receptor Ile269Asn Mutation on Weight Loss Response to Dietary, Phentermine and Bariatric Surgery Interventions.
Salazar-Valencia IG, Villamil-Ramírez H, Barajas-Olmos F, Guevara-Cruz M, Macias-Kauffer LR, García-Ortiz H, Hernández-Vergara O, Díaz de Sandy-Galán DA, León-Mimila P, Centeno-Cruz F, González-Salazar LE, Guizar-Heredia R, Pichardo-Ontiveros E, Jacobo-Albavera L, Posadas-Sánchez R, Vargas-Alarcón G, Velazquez-Cruz R, Gutiérrez-Aguilar R, Zerrweck C, Rocha-González HI, Reyes-García JG, Carrasco-Portugal MDC, Flores-Murrieta FJ, Tovar AR, Orozco L, Villarreal-Molina T, Canizales-Quinteros S., Free PMC Article | 01/11/2023 |
| The Role of Dietary Glycemic Index and Glycemic Load in Mediating Genetic Susceptibility via MC4R s17782313 Genotypes to Affect Cardiometabolic Risk Factors among Apparently Healthy Obese Individuals. | The Role of Dietary Glycemic Index and Glycemic Load in Mediating Genetic Susceptibility via MC4R s17782313 Genotypes to Affect Cardiometabolic Risk Factors among Apparently Healthy Obese Individuals.
Khodarahmi M, Siri G, Mohammadi M, Farhangi MA, Aleseidi S., Free PMC Article | 12/3/2022 |
| Functional alterations of two novel MC4R mutations found in Argentinian pediatric patients with early onset obesity. | Functional alterations of two novel MC4R mutations found in Argentinian pediatric patients with early onset obesity.
Fernández E, McCarthy CI, Cerviño RH, Rodríguez SS, Yaneff A, Hernández J, Garrido V, Di Rocco F, Raingo J. | 11/26/2022 |
| Melanocortin-4 receptors activate sympathetic preganglionic neurons and elevate blood pressure via TRPV1. | Melanocortin-4 receptors activate sympathetic preganglionic neurons and elevate blood pressure via TRPV1.
Ju SH, Yun H, Oh Y, Choi Y, Sohn JW. | 11/12/2022 |
| Structural analysis of setmelanotide binding to MC4R variants in comparison to wild-type receptor. | Structural analysis of setmelanotide binding to MC4R variants in comparison to wild-type receptor.
Hammad MM, Mohammad A, Alam-Eldin N, Madhu D, Al-Mulla F, Abu-Farha M, Abubaker J. | 10/15/2022 |
| Are there any interactions between modified Nordic-style diet score and MC4R polymorphism on cardiovascular risk factors among overweight and obese women? A cross-sectional study. | Are there any interactions between modified Nordic-style diet score and MC4R polymorphism on cardiovascular risk factors among overweight and obese women? A cross-sectional study.
Hosseininasab D, Mirzababaei A, Abaj F, Firoozi R, Clark CCT, Mirzaei K., Free PMC Article | 09/10/2022 |
| The interaction between Alternative Healthy Eating Index and MC4R rs17782313 gene variants on central and general obesity indices in women: A cross-sectional study. | The interaction between Alternative Healthy Eating Index and MC4R rs17782313 gene variants on central and general obesity indices in women: A cross-sectional study.
Zarei M, Shiraseb F, Mirzababaei A, Mirzaei K. | 08/13/2022 |
| Molecular Analysis and Conformational Dynamics of Human MC4R Disease-Causing Mutations. | Molecular Analysis and Conformational Dynamics of Human MC4R Disease-Causing Mutations.
Fatima MT, Islam Z, Kolatkar PR, Al-Shabeeb Akil AS., Free PMC Article | 07/23/2022 |
| The rs483145 polymorphism of MC4R gene is not associated with obesity in the Chilean population: Results of GENADIO study. | The rs483145 polymorphism of MC4R gene is not associated with obesity in the Chilean population: Results of GENADIO study.
Mardones L, Parra-Valencia E, Petermann-Rocha F, Martínez-Sanguinetti MA, Leiva-Ordoñez AM, Lasserre-Laso N, Martorell M, Ulloa N, Sanhueza E, Pérez-Bravo F, Celis-Morales C, Villagrán M, ELHOC research group (Epidemiology of Lifestyle, Health Outcomes in Chile). | 06/11/2022 |