| Orbit/CLASP determines centriole length by antagonising Klp10A in Drosophila spermatocytes. | Orbit/CLASP determines centriole length by antagonising Klp10A in Drosophila spermatocytes.
Shoda T, Yamazoe K, Tanaka Y, Asano Y, Inoue YH., Free PMC Article | 07/24/2021 |
| Findings suggest that Msps is a novel Rac effector that acts, in partnership with Orbit, to regionally regulate microtubule dynamics. | TOG Proteins Are Spatially Regulated by Rac-GSK3β to Control Interphase Microtubule Dynamics.
Trogden KP, Rogers SL., Free PMC Article | 05/28/2016 |
| Orbit plays an essential role as a connector between microtubules and the contractile ring in Drosophila male meiosis. | Orbit/CLASP is required for myosin accumulation at the cleavage furrow in Drosophila male meiosis.
Kitazawa D, Matsuo T, Kaizuka K, Miyauchi C, Hayashi D, Inoue YH., Free PMC Article | 06/20/2015 |
| Orbit is involved in the proper orientation of spindles towards fusomes during synchronous mitosis of spermatogonial cysts. | Orbit/CLASP is required for germline cyst formation through its developmental control of fusomes and ring canals in Drosophila males.
Miyauchi C, Kitazawa D, Ando I, Hayashi D, Inoue YH., Free PMC Article | 09/14/2013 |
| Data suggest a model in which CLASP and Msps converge in an antagonistic balance in the Abl signaling pathway. | Parallel genetic and proteomic screens identify Msps as a CLASP-Abl pathway interactor in Drosophila.
Lowery LA, Lee H, Lu C, Murphy R, Obar RA, Zhai B, Schedl M, Van Vactor D, Zhan Y., Free PMC Article | 02/26/2011 |
| Dynein and mast/orbit/CLASP have antagonistic roles in regulating kinetochore-microtubule plus-end dynamics. | Dynein and mast/orbit/CLASP have antagonistic roles in regulating kinetochore-microtubule plus-end dynamics.
Reis R, Feijão T, Gouveia S, Pereira AJ, Matos I, Sampaio P, Maiato H, Sunkel CE. | 01/21/2010 |
| results suggest that Mast plays an essential role in reducing the dynamic behaviour of microtubules by specifically promoting the pause state | The Drosophila CLASP homologue, Mast/Orbit regulates the dynamic behaviour of interphase microtubules by promoting the pause state.
Sousa A, Reis R, Sampaio P, Sunkel CE. | 01/21/2010 |
| is an essential component for microtubule subunit incorporation into fluxing K-fibres | Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres.
Maiato H, Khodjakov A, Rieder CL., Free PMC Article | 01/21/2010 |
| MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity. | MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity.
Maiato H, Sampaio P, Lemos CL, Findlay J, Carmena M, Earnshaw WC, Sunkel CE., Free PMC Article | 01/21/2010 |
| Orbit/Mast/CLASP localizes to interior rather than peripheral central spindle microtubules | Mutations in orbit/mast reveal that the central spindle is comprised of two microtubule populations, those that initiate cleavage and those that propagate furrow ingression.
Inoue YH, Savoian MS, Suzuki T, Máthé E, Yamamoto MT, Glover DM., Free PMC Article | 01/21/2010 |
| Data show that the Orbit/Mast microtubule-associated protein is required at several stages in Drosophila oocyte cell differentiation. | Orbit/Mast, the CLASP orthologue of Drosophila, is required for asymmetric stem cell and cystocyte divisions and development of the polarised microtubule network that interconnects oocyte and nurse cells during oogenesis.
Máthé E, Inoue YH, Palframan W, Brown G, Glover DM. | 01/21/2010 |