inducing expression of Cut in stage 14 follicle cells is sufficient to inhibit follicle rupture and ovulation through its negative regulation of Hnt and promotion of Ttk69 expression. | Downregulation of homeodomain protein Cut is essential for Drosophila follicle maturation and ovulation. Knapp EM, Li W, Sun J., Free PMC Article | 06/27/2020 |
These analyses identified a host of putative Cut and/or Knot effector molecules, and a subset of these putative TF targets converge on modulating dendritic cytoskeletal architecture, which are grouped into three major phenotypic categories, based upon neuromorphometric analyses: complexity enhancer, complexity shifter, and complexity suppressor | Dendritic Cytoskeletal Architecture Is Modulated by Combinatorial Transcriptional Regulation in Drosophila melanogaster. Das R, Bhattacharjee S, Patel AA, Harris JM, Bhattacharya S, Letcher JM, Clark SG, Nanda S, Iyer EPR, Ascoli GA, Cox DN., Free PMC Article | 07/21/2018 |
and ecdysone signaling pathways synergistically regulate Cut expression for proper DV boundary formation in the wing disc | The Ecdysone and Notch Pathways Synergistically Regulate Cut at the Dorsal-Ventral Boundary in Drosophila Wing Discs. Jia D, Bryant J, Jevitt A, Calvin G, Deng WM., Free PMC Article | 10/28/2017 |
Loss of Ct and Hth in the antenna disc resulted in ectopic eye development in the antenna. | Segregation of eye and antenna fates maintained by mutual antagonism in Drosophila. Wang CW, Sun YH. | 11/3/2012 |
Drosophila transcription factor Cut coordinately controls differentiation and repression of apoptosis via direct regulation of the pro-apoptotic gene | Antagonistic regulation of apoptosis and differentiation by the Cut transcription factor represents a tumor-suppressing mechanism in Drosophila. Zhai Z, Ha N, Papagiannouli F, Hamacher-Brady A, Brady N, Sorge S, Bezdan D, Lohmann I., Free PMC Article | 09/8/2012 |
Turtle is downstream effector of Cut-mediated regulation of da neuron dendrite morphology. | Turtle functions downstream of Cut in differentially regulating class specific dendrite morphogenesis in Drosophila. Sulkowski MJ, Iyer SC, Kurosawa MS, Iyer EP, Cox DN., Free PMC Article | 12/10/2011 |
Study of distant interactions of LCR from the locus CUT. | Study of distant interactions of LCR from the Drosophila melanogaster locus CUT. Sosin DV, Moiseeva ED, Tchurikov NA. | 11/6/2010 |
Opposing interactions between Drosophila cut and the C/EBP encoded by slow border cells direct apical constriction and epithelial invagination | Opposing interactions between Drosophila cut and the C/EBP encoded by slow border cells direct apical constriction and epithelial invagination. Levine B, Hackney JF, Bergen A, Dobens L 3rd, Truesdale A, Dobens L. | 08/16/2010 |
cut protein acts in parallel to atonal, spalt-major and spalt-related transcription factors for differentiation of Johnston's organ of Drosophila antennae. | Cut mutant Drosophila auditory organs differentiate abnormally and degenerate. Ebacher DJ, Todi SV, Eberl DF, Boekhoff-Falk GE., Free PMC Article | 01/21/2010 |
cut control the dendrite cytoskeleton and synergize to define final arbor shape. | Knot/Collier and cut control different aspects of dendrite cytoskeleton and synergize to define final arbor shape. Jinushi-Nakao S, Arvind R, Amikura R, Kinameri E, Liu AW, Moore AW. | 01/21/2010 |
Cut functions in regulating both cell differentiation and the cell cycle, and downregulation of Cut by Notch contributes to the mitotic cycle/endocycle switch and cell differentiation in follicle cells. | Notch-dependent downregulation of the homeodomain gene cut is required for the mitotic cycle/endocycle switch and cell differentiation in Drosophila follicle cells. Sun J, Deng WM., Free PMC Article | 01/21/2010 |
Data show that Nipped-B is required for sister chromatid cohesion but that, opposite to the effect of Nipped-B, the stromalin/Scc3 component of Cohesin inhibits long-range activation of cut. | Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene. Rollins RA, Korom M, Aulner N, Martens A, Dorsett D., Free PMC Article | 01/21/2010 |
bft acts downstream of cut and tramtrack to implement correct bristle morphogenesis | The bereft gene, a potential target of the neural selector gene cut, contributes to bristle morphogenesis. Hardiman KE, Brewster R, Khan SM, Deo M, Bodmer R., Free PMC Article | 01/21/2010 |
These results indicate that Cut functions as a transcriptional repressor of dPCNA gene by binding to the promoter region in the differentiated state | Antagonistic regulation of the Drosophila PCNA gene promoter by DREF and Cut. Seto H, Hayashi Y, Kwon E, Taguchi O, Yamaguchi M. | 01/21/2010 |
Gene loci that interact with cut during Drosophila wing-margin development were identified. | Identification of genetic loci that interact with cut during Drosophila wing-margin development. Krupp JJ, Yaich LE, Wessells RJ, Bodmer R., Free PMC Article | 01/21/2010 |