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    OGG1 8-oxoguanine DNA glycosylase [ Homo sapiens (human) ]

    Gene ID: 4968, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles.

    Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles.
    Ren M, Gut F, Fan Y, Ma J, Shan X, Yikilmazsoy A, Likhodeeva M, Hopfner KP, Zhou C., Free PMC Article

    11/6/2024
    8-Oxoguanine DNA Glycosylase1 conceals oxidized guanine in nucleoprotein-associated RNA of respiratory syncytial virus.

    8-Oxoguanine DNA Glycosylase1 conceals oxidized guanine in nucleoprotein-associated RNA of respiratory syncytial virus.
    Pan L, Wang K, Hao W, Xue Y, Zheng X, Basu RS, Hazra TK, Islam A, Hosakote Y, Tian B, Gagnon MG, Ba X, Boldogh I., Free PMC Article

    11/5/2024
    OGG1: An emerging multifunctional therapeutic target for the treatment of diseases caused by oxidative DNA damage.

    OGG1: An emerging multifunctional therapeutic target for the treatment of diseases caused by oxidative DNA damage.
    Zhong Y, Zhang X, Feng R, Fan Y, Zhang Z, Zhang QW, Wan JB, Wang Y, Yu H, Li G.

    10/9/2024
    Human 8-oxoguanine glycosylase OGG1 binds nucleosome at the dsDNA ends and the super-helical locations.

    Human 8-oxoguanine glycosylase OGG1 binds nucleosome at the dsDNA ends and the super-helical locations.
    You Q, Feng X, Cai Y, Baylin SB, Li H., Free PMC Article

    10/3/2024
    OGG1 prevents atherosclerosis-induced vascular endothelial cell injury through mediating DNA damage repair.

    OGG1 prevents atherosclerosis-induced vascular endothelial cell injury through mediating DNA damage repair.
    Zhang YM, Wang GH, Xu MJ, Jin G.

    07/22/2024
    SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner.

    SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner.
    Geng A, Sun J, Tang H, Yu Y, Wang X, Zhang J, Wang X, Sun X, Zhou X, Gao N, Tan R, Xu Z, Jiang Y, Mao Z., Free PMC Article

    06/10/2024
    Association between polymorphisms of the DNA repair genes RAD51 and OGG1 and risk of cardiovascular disease.

    Association between polymorphisms of the DNA repair genes RAD51 and OGG1 and risk of cardiovascular disease.
    Alomair A, Alamri A, Shaik J, Aljafari S, Ba Abdullah M, Alanazi M., Free PMC Article

    02/26/2024
    Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1.

    Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1.
    Schaich MA, Weaver TM, Roginskaya V, Freudenthal BD, Van Houten B.,

    02/21/2024
    The 24-h profile of the DNA repair enzyme 8-oxoguanine glycosylase 1 (OGG1) is associated with age, TNF-alpha, and waist circumference in healthy adults.

    The 24-h profile of the DNA repair enzyme 8-oxoguanine glycosylase 1 (OGG1) is associated with age, TNF-α, and waist circumference in healthy adults.
    Arkenberg P, Dittmar M., Free PMC Article

    02/8/2024
    Investigation of APE1 and OGG1 expression in chronic hemodialysis patients.

    Investigation of APE1 and OGG1 expression in chronic hemodialysis patients.
    Rostami M, Yalin SF, Altiparmak MR, Guven M.

    02/7/2024
    8-Oxoguanine DNA glycosylase 1 selectively modulates ROS-responsive NF-kappaB targets through recruitment of MSK1 and phosphorylation of RelA/p65 at Ser276.

    8-Oxoguanine DNA glycosylase 1 selectively modulates ROS-responsive NF-κB targets through recruitment of MSK1 and phosphorylation of RelA/p65 at Ser276.
    Xue Y, Li C, Deng S, Chen X, Han J, Zheng X, Tian M, Hao W, Pan L, Boldogh I, Ba X, Wang R., Free PMC Article

    11/30/2023
    Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells.

    Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells.
    D'Augustin O, Gaudon V, Siberchicot C, Smith R, Chapuis C, Depagne J, Veaute X, Busso D, Di Guilmi AM, Castaing B, Radicella JP, Campalans A, Huet S., Free PMC Article

    06/13/2023
    Mitochondrial OGG1 expression reduces age-associated neuroinflammation by regulating cytosolic mitochondrial DNA.

    Mitochondrial OGG1 expression reduces age-associated neuroinflammation by regulating cytosolic mitochondrial DNA.
    Hussain M, Chu X, Duan Sahbaz B, Gray S, Pekhale K, Park JH, Croteau DL, Bohr VA., Free PMC Article

    06/12/2023
    8-Oxoguanine DNA Glycosylase 1 Upregulation as a Risk Factor for Obesity and Colorectal Cancer.

    8-Oxoguanine DNA Glycosylase 1 Upregulation as a Risk Factor for Obesity and Colorectal Cancer.
    Pilo J, García-Flores LA, Clemente-Postigo M, Arranz-Salas I, Alcaide J, Ramos-Fernandez M, Lozano J, Boughanem H, Kompella P, Macías-González M., Free PMC Article

    03/31/2023
    PARP1 and OGG1 in Medicated Patients With Depression and the Response to ECT.

    PARP1 and OGG1 in Medicated Patients With Depression and the Response to ECT.
    Ryan KM, McLoughlin DM., Free PMC Article

    02/27/2023
    Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.

    Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.
    Shang Q, Pan C, Zhang X, Yang T, Hu T, Zheng L, Cao S, Feng C, Hu X, Chai X, Wang J, Fang Q., Free PMC Article

    02/4/2023
    OGG1 in the Kidney: Beyond Base Excision Repair.

    OGG1 in the Kidney: Beyond Base Excision Repair.
    Zhao F, Zhu J, Shi L, Wu X., Free PMC Article

    01/14/2023
    Assessment of hOGG1 Genetic Polymorphism (rs1052133) and DNA Damage in Radiation-Exposed Workers.

    Assessment of hOGG1 Genetic Polymorphism (rs1052133) and DNA Damage in Radiation-Exposed Workers.
    Surniyantoro HNE, Yusuf D, Rahardjo T, Rahajeng N, Kisnanto T, Nurhayati S, Lusiyanti Y, Syaifudin M, Hande MP., Free PMC Article

    01/11/2023
    hOGG1 rs1052133 Polymorphism and Prostate Cancer Risk: A Chinese Case-Control Study and Meta-Analysis.

    hOGG1 rs1052133 Polymorphism and Prostate Cancer Risk: A Chinese Case-Control Study and Meta-Analysis.
    Xu H, Zhang M, Hao Z, Liang C., Free PMC Article

    11/5/2022
    Direct hOGG1-Myc interactions inhibit hOGG1 catalytic activity and recruit Myc to its promoters under oxidative stress.

    Direct hOGG1-Myc interactions inhibit hOGG1 catalytic activity and recruit Myc to its promoters under oxidative stress.
    Bangalore DM, Tessmer I., Free PMC Article

    10/22/2022
    Expression variation of OGG1 and HPRT gene and DNA damage in arsenic exposed industrial workers.

    Expression variation of OGG1 and HPRT gene and DNA damage in arsenic exposed industrial workers.
    Akram Z, Mahjabeen I, Umair M, Fahim M, Kayani MA, Fatima L, Ahmad MW, Jahan S, Afsar T, Almajwal A, Alruwaili NW, Khawar IA, Razak S., Free PMC Article

    10/15/2022
    Association of base excision repair pathway genes OGG1, XRCC1 and MUTYH polymorphisms and the level of 8-oxo-guanine with increased risk of colorectal cancer occurrence.

    Association of base excision repair pathway genes OGG1, XRCC1 and MUTYH polymorphisms and the level of 8-oxo-guanine with increased risk of colorectal cancer occurrence.
    Kabziński J, Majsterek I., Free PMC Article

    10/15/2022
    RELA8-Oxoguanine DNA Glycosylase1 Is an Epigenetic Regulatory Complex Coordinating the Hexosamine Biosynthetic Pathway in RSV Infection.

    RELA∙8-Oxoguanine DNA Glycosylase1 Is an Epigenetic Regulatory Complex Coordinating the Hexosamine Biosynthetic Pathway in RSV Infection.
    Xu X, Qiao D, Pan L, Boldogh I, Zhao Y, Brasier AR., Free PMC Article

    08/13/2022
    OGG1 contributes to hepatocellular carcinoma by promoting cell cycle-related protein expression and enhancing DNA oxidative damage repair in tumor cells.

    OGG1 contributes to hepatocellular carcinoma by promoting cell cycle-related protein expression and enhancing DNA oxidative damage repair in tumor cells.
    Zhang H, Jiang PJ, Lv MY, Zhao YH, Cui J, Chen J., Free PMC Article

    07/23/2022
    Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases MUTYH and hOGG1 in Colorectal Cancer Patients.

    Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases MUTYH and hOGG1 in Colorectal Cancer Patients.
    Kavec MJ, Urbanova M, Makovicky P, Opattová A, Tomasova K, Kroupa M, Kostovcikova K, Siskova A, Navvabi N, Schneiderova M, Vymetalkova V, Vodickova L, Vodicka P., Free PMC Article

    06/11/2022
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