| Transient Receptor Potential Vanilloid 3 (TRPV3) in the Cerebellum of Rat and Its Role in Motor Coordination. | Transient Receptor Potential Vanilloid 3 (TRPV3) in the Cerebellum of Rat and Its Role in Motor Coordination.
Singh U, Upadhya M, Basu S, Singh O, Kumar S, Kokare DM, Singru PS. | 12/12/2020 |
| MiR-103 could attenuate cardiomyocyte hypertrophy partly by reducing cardiac autophagy activity through the targeted inhibition of TRPV3 signalling. | MiR-103 inhibiting cardiac hypertrophy through inactivation of myocardial cell autophagy via targeting TRPV3 channel in rat hearts.
Qi H, Ren J, E M, Zhang Q, Cao Y, Ba L, Song C, Shi P, Fu B, Sun H., Free PMC Article | 06/27/2020 |
| the activation of TRPV3 aggravated pathological cardiac hypertrophy through calcineurin/NFATc3 signalling pathway and correlated with the protein expression levels of calcineurin, phosphorylated CaMKII and NFATc3, revealing that TRPV3 might be a potential therapeutic target for cardiac hypertrophy. | Activation of transient receptor potential vanilloid 3 channel (TRPV3) aggravated pathological cardiac hypertrophy via calcineurin/NFATc3 pathway in rats.
Zhang Q, Qi H, Cao Y, Shi P, Song C, Ba L, Chen Y, Gao J, Li S, Li B, Sun H., Free PMC Article | 11/2/2019 |
| Activation of the peripheral ion channel TRPM8 with menthol and rapid cooling (decrease in body temperature by 3C) led to 1.5-fold activation of the expression of TRPV3 ion channel gene in the posterior hypothalamus, but had no effect on the expression of this gene in the anterior hypothalamus. | Effect of Activation of Peripheral Ion Channel TRPM8 on Gene Expression of Thermosensitive TRP Ion Channels in the Hypothalamus. Comparison with the Effect of Cooling.
Kozyreva TV, Evtushenko AA, Voronova IP, Khramova GM, Kozaruk VP. | 03/23/2019 |
| TRPV3 activation exacerbated cardiac fibrosis by promoting cardiac fibroblast proliferation through the TGF-beta1 pathway. | Transient receptor potential vanilloid-3 (TRPV3) activation plays a central role in cardiac fibrosis induced by pressure overload in rats via TGF-β(1) pathway.
Liu Y, Qi H, E M, Shi P, Zhang Q, Li S, Wang Y, Cao Y, Chen Y, Ba L, Gao J, Huang W, Sun H. | 08/18/2018 |
| TRPV3 is involved in hypoxia-induced pulmonary vascular remodeling and promotes proliferation of pulmonary artery smooth muscle cells and the effect is, at least in part, mediated via the PI3K/AKT pathway. | The transient receptor potential vanilloid-3 regulates hypoxia-mediated pulmonary artery smooth muscle cells proliferation via PI3K/AKT signaling pathway.
Zhang Q, Cao Y, Luo Q, Wang P, Shi P, Song C, E M, Ren J, Fu B, Sun H., Free PMC Article | 06/30/2018 |
| Antagonism of TRPV3 receptors modulates activity of key classes of neurons in the pain pathway in a manner consistent with limiting pathological nociceptive signaling and was mediated by receptors in the periphery and brain. Blockade of TRPV3 receptors is likely an effective means to alleviate mechanical allodynia and nonevoked pain by blocking supraspinal TRPV3 receptors. | TRPV3 modulates nociceptive signaling through peripheral and supraspinal sites in rats.
McGaraughty S, Chu KL, Xu J, Leys L, Radek RJ, Dart MJ, Gomtsyan A, Schmidt RG, Kym PR, Brederson JD., Free PMC Article | 04/28/2018 |
| Results demonstrate a role for TRPV3 in driving mesolimbic-dopamine food-reward pathway, and underscores the importance of these channels in the ventral tegmental area as key components processing reward. | Transient receptor potential vanilloid 3 (TRPV3) in the ventral tegmental area of rat: Role in modulation of the mesolimbic-dopamine reward pathway.
Singh U, Kumar S, Shelkar GP, Yadav M, Kokare DM, Goswami C, Lechan RM, Singru PS. | 02/24/2018 |
| It was concluded that TRPV3 is expressed in a discrete subpopulation of vagal afferent neurons and may contribute to vagal afferent signaling either directly or in combination with TRPV1. | Genetic and pharmacological evidence for low-abundance TRPV3 expression in primary vagal afferent neurons.
Wu SW, Lindberg JE, Peters JH., Free PMC Article | 07/1/2017 |
| TRPV3 caused an endothelium-independent, IKCa-mediated dilation of the uterine radial artery. NO-PKG-mediated modulation of TRPV3 activity is lost in pregnancy, but this did not alter the response to vasodilator carvacrol. | TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats.
Murphy TV, Kanagarajah A, Toemoe S, Bertrand PP, Grayson TH, Britton FC, Leader L, Senadheera S, Sandow SL. | 06/10/2017 |
| findings suggest that although TRPV3 agonism induces hypothermia in rodents, it may have a limited potential as a novel pharmacological method for induction of hypothermia | Systemic Administration of the TRPV3 Ion Channel Agonist Carvacrol Induces Hypothermia in Conscious Rodents.
Feketa VV, Marrelli SP., Free PMC Article | 06/11/2016 |
| Demonstrate similarities but also notable differences in TRPV3 pharmacology between recombinant and native systems. | Pharmacological profiling of the TRPV3 channel in recombinant and native assays.
Grubisha O, Mogg AJ, Sorge JL, Ball LJ, Sanger H, Ruble CL, Folly EA, Ursu D, Broad LM., Free PMC Article | 12/20/2014 |
| Long-term cold adaptation modified the gene expression of TRPV3 ion channel. | [Thermosensitive TRP channels gene expression in hypothalamus of normal rats and rats adapted to cold].
Voronova IP, Tuzhikova AA, Kozyreva TV. | 01/26/2013 |
| Polymerase chain reaction used to check the expression of all TRPM and TRPV channel members with specific primers. | Distribution profiles of transient receptor potential melastatin-related and vanilloid-related channels in prostatic tissue in rat.
Wang HP, Pu XY, Wang XH. | 12/6/2011 |
| TRPV1, V2, and V3 channels are expressed on these sensory neurons and their terminals. | 2-aminoethoxydiphenyl borate stimulates pulmonary C neurons via the activation of TRPV channels.
Gu Q, Lin RL, Hu HZ, Zhu MX, Lee LY., Free PMC Article | 01/21/2010 |
| TRPV3 was the gene responsible for Nh and Ht mutations, and mutation in TRPV3 possibly correlated with increased mast cell numbers. | Association of a mutation in TRPV3 with defective hair growth in rodents.
Asakawa M, Yoshioka T, Matsutani T, Hikita I, Suzuki M, Oshima I, Tsukahara K, Arimura A, Horikawa T, Hirasawa T, Sakata T. | 01/21/2010 |