The present study revealed that one of the major rHuOVGP1-enhanced pY proteins could be AKAP3 of the FS and that rHuOVGP1 is capable of binding to human ZP and its presence in the medium results in an increase in sperm-zona binding. Supplement of rHuOVGP1 in in vitro fertilization media could be beneficial for enhancement of the fertilizing ability of human sperm. | Human OVGP1 enhances tyrosine phosphorylation of proteins in the fibrous sheath involving AKAP3 and increases sperm-zona binding. Zhao Y, Kan FWK., Free PMC Article | 12/14/2019 |
OVGP1 is specifically induced in the luminal epithelium at the time of embryo implantation where it regulates receptivity-related genes and aids in trophoblast adhesion. | Oviductal glycoprotein 1 (OVGP1) is expressed by endometrial epithelium that regulates receptivity and trophoblast adhesion. Laheri S, Ashary N, Bhatt P, Modi D., Free PMC Article | 11/10/2018 |
Decreased gene expression of MUC9 was found from colonic biopsies in patients with active and remission ulcerative colitis. | Reduced expression of mucin 9 (MUC9) in patients with ulcerative colitis. Yamamoto-Furusho JK, Mendivil EJ, Fonseca-Camarillo G. | 06/23/2012 |
Observational study of gene-disease association. (HuGE Navigator) | Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A. | 12/5/2010 |
OVGP1 seems to detect a different spectrum of ovarian epithelial cancers than other markers and thus should be a useful adjunct for more accurate detection, particularly of early serous ovarian cancers and mucinous carcinomas. | Oviductal glycoprotein (OVGP1, MUC9): a differentiation-based mucin present in serum of women with ovarian cancer. Maines-Bandiera S, Woo MM, Borugian M, Molday LL, Hii T, Gilks B, Leung PC, Molday RS, Auersperg N. | 05/3/2010 |
Reflux laryngitis is associated with down-regulation of mucin gene expression. | Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux. Samuels TL, Handler E, Syring ML, Pajewski NM, Blumin JH, Kerschner JE, Johnston N. | 01/21/2010 |
Gain of oviduct-specific glycoprotein is associated with the development of endometrial hyperplasia and endometrial cancer | Gain of OGP, an estrogen-regulated oviduct-specific glycoprotein, is associated with the development of endometrial hyperplasia and endometrial cancer. Woo MM, Alkushi A, Verhage HG, Magliocco AM, Leung PC, Gilks CB, Auersperg N. | 01/21/2010 |
The presence of oviductin mRNA and protein has been determined in OE-E6/E7, an immortalized human oviductal epithelial cell line. | Expression of human oviductin in an immortalized human oviductal cell line. Ling L, Lee YL, Lee KF, Tsao SW, Yeung WS, Kan FW. | 01/21/2010 |
The production and function of oviductin at different stages of human reproductive cycle is not well known. Its highest expression at the time of ovulation is consistent with a supportive role in fertilization and early embryo development. | Variable expression of oviductin mRNA at different stages of human reproductive cycle. Lok IH, Briton-Jones CM, Yuen PM, Haines CJ., Free PMC Article | 01/21/2010 |
Results suggests the binding of OGP to human sperm mediates through MYH9. | Identification and characterization of oviductal glycoprotein-binding protein partner on gametes: epitopic similarity to non-muscle myosin IIA, MYH 9. Kadam KM, D'Souza SJ, Bandivdekar AH, Natraj U. | 01/21/2010 |
cloning and characterization of the promoter and gene expression regulation in the oviduct (human oviduct-specific glycoprotein, HuOPG) | Cloning and characterization of the human oviduct-specific glycoprotein (HuOGP) gene promoter. Agarwal A, Yeung WS, Lee KF. | 01/21/2010 |