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    IL22 interleukin 22 [ Homo sapiens (human) ]

    Gene ID: 50616, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Interleukin-22 improves ovulation in polycystic ovary syndrome via STAT3 signaling.

    Interleukin-22 improves ovulation in polycystic ovary syndrome via STAT3 signaling.
    Liao B, Chen W, Qi X, Yun C, Pang Y.

    11/6/2024
    IL-22 promotes mucin-type O-glycosylation and MATH1[+] cell-mediated amelioration of intestinal inflammation.

    IL-22 promotes mucin-type O-glycosylation and MATH1(+) cell-mediated amelioration of intestinal inflammation.
    Singh A, Beaupre M, Villegas-Novoa C, Shiomitsu K, Gaudino SJ, Tawch S, Damle R, Kempen C, Choudhury B, McAleer JP, Sheridan BS, Denoya P, Blumberg RS, Hearing P, Allbritton NL, Kumar P., Free PMC Article

    09/24/2024
    The role of IL-22 in cancer.

    The role of IL-22 in cancer.
    Hunzeker ZE, Zhao L, Kim AM, Parker JM, Zhu Z, Xiao H, Bai Q, Wakefield MR, Fang Y.

    09/12/2024
    The evolving landscape of IL-10, IL-22 and IL-26 in pleurisy especially in tuberculous pleurisy.

    The evolving landscape of IL-10, IL-22 and IL-26 in pleurisy especially in tuberculous pleurisy.
    Niu Q, Wang M, Liu XS., Free PMC Article

    07/31/2024
    Expression and diagnostic value of interleukin-22 in rheumatoid arthritis-associated interstitial lung disease.

    Expression and diagnostic value of interleukin-22 in rheumatoid arthritis-associated interstitial lung disease.
    Fang Q, Xie J, Zong J, Zhou Y, Zhou Q, Yin S, Cao L, Yin H, Zhou D.

    06/10/2024
    Expression and function of cytokine interleukin-22 gene in the tumor microenvironment of triple negative breast cancer.

    Expression and function of cytokine interleukin-22 gene in the tumor microenvironment of triple negative breast cancer.
    Xiao Y, Zhao X, Guo Y, Li Y.

    05/28/2024
    Interleukin-22 inhibits cardiac fibrosis by regulating fibroblast metabolic reprogramming in myocardial infarction.

    Interleukin-22 inhibits cardiac fibrosis by regulating fibroblast metabolic reprogramming in myocardial infarction.
    Liu F, Chen Y, Qin D, Qian C.

    04/18/2024
    Interleukin-22 enhanced the mucosal barrier and inhibited the invasion of Salmonella enterica in human-induced pluripotent stem cell-derived small intestinal epithelial cells.

    Interleukin-22 enhanced the mucosal barrier and inhibited the invasion of Salmonella enterica in human-induced pluripotent stem cell-derived small intestinal epithelial cells.
    Yamazaki F, Kobayashi K, Mochizuki J, Sashihara T.

    02/15/2024
    Unraveling IL-17 and IL-22 role in occult hepatitis C versus chronic hepatitis C virus infection.

    Unraveling IL-17 and IL-22 role in occult hepatitis C versus chronic hepatitis C virus infection.
    Elbaz S, Mousa N, Elmetwalli A, Abdel-Razik A, Salah M, ElHammady A, Abdelsalam M, Abdelkader E, El-Wakeel N, Eldars W, El-Emam O, Elbeltagy A, Shaheen M, El-Zamek H, Mousa E, Deiab A, Elgamal A, Habib A., Free PMC Article

    02/7/2024
    Pro-osteogenic role of interleukin-22 in calcific aortic valve disease.

    Pro-osteogenic role of interleukin-22 in calcific aortic valve disease.
    Deng H, Li H, Liu Z, Shen N, Dong N, Deng C, Liu F.

    02/5/2024
    IL-22 is secreted by proximal tubule cells and regulates DNA damage response and cell death in acute kidney injury.

    IL-22 is secreted by proximal tubule cells and regulates DNA damage response and cell death in acute kidney injury.
    Taguchi K, Sugahara S, Elias BC, Pabla NS, Canaud G, Brooks CR.,

    01/8/2024
    Gut microbiota-mediated IL-22 alleviates metabolic inflammation.

    Gut microbiota-mediated IL-22 alleviates metabolic inflammation.
    Wang K, Zhou M, Si H, Ma J.

    11/30/2023
    Interleukin-22 and acute pancreatitis: A review.

    Interleukin-22 and acute pancreatitis: A review.
    Fu X, Xiu Z, Xu H., Free PMC Article

    11/28/2023
    Interleukin-22 Inhibits Apoptosis of Gingival Epithelial Cells Through TGF-beta Signaling Pathway During Periodontitis.

    Interleukin-22 Inhibits Apoptosis of Gingival Epithelial Cells Through TGF-β Signaling Pathway During Periodontitis.
    Huang Y, Zhang L, Tan L, Zhang C, Li X, Wang P, Gao L, Zhao C.

    11/8/2023
    CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis.

    CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis.
    Zhang T, Wahib R, Zazara DE, Lücke J, Shiri AM, Kempski J, Zhao L, Agalioti T, Machicote AP, Giannou O, Belios I, Jia R, Zhang S, Tintelnot J, Seese H, Grass JK, Mercanoglu B, Stern L, Scognamiglio P, Fard-Aghaie M, Seeger P, Wakker J, Kemper M, Brunswig B, Duprée A, Lykoudis PM, Pikouli A, Giorgakis E, Stringa P, Lausada N, Gentilini MV, Gondolesi GE, Bachmann K, Busch P, Grotelüschen R, Maroulis IC, Arck PC, Nakano R, Thomson AW, Ghadban T, Tachezy M, Melling N, Achilles EG, Puelles VG, Nickel F, Hackert T, Mann O, Izbicki JR, Li J, Gagliani N, Huber S, Giannou AD., Free PMC Article

    10/28/2023
    Screening of IL-22 first and second introns and FOXP3 second exon for SNPs and mutations with potential role in the susceptibility of SLE in selected population.

    Screening of IL-22 first and second introns and FOXP3 second exon for SNPs and mutations with potential role in the susceptibility of SLE in selected population.
    Hussain N, Aneela S, Aqsa N, Saeed A, Aziz T, Majid A, Abdulhakeem SA, Al-Abbas NS, Shaer NA, Barqawi AA, Alghamdi S, Shakoori A, Alshareef SA.

    10/24/2023
    Expression and Clinical Significance of Peripheral Blood IL-17A, IL-22, Tim-3, and gal-9 in Children with Infectious Mononucleosis.

    Expression and Clinical Significance of Peripheral Blood IL-17A, IL-22, Tim-3, and gal-9 in Children with Infectious Mononucleosis.
    Xu M, Li Y, Cao M, Su Y, Ji Z, Zhou W.

    09/20/2023
    Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis.

    Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis.
    Wagner F, Mansfield JC, Lekkerkerker AN, Wang Y, Keir M, Dash A, Butcher B, Harder B, Orozco LD, Mar JS, Chen H, Rothenberg ME., Free PMC Article

    08/4/2023
    MiR-149-5p inhibits cell proliferation, promotes cell apoptosis and retards cell cycle of IL-22-stimulated HaCaT and NHEK keratinocytes via regulating PDE4D.

    MiR-149-5p inhibits cell proliferation, promotes cell apoptosis and retards cell cycle of IL-22-stimulated HaCaT and NHEK keratinocytes via regulating PDE4D.
    Hu W, Jiang Y, Wen C, Zeng Y, Jia M.

    03/20/2023
    The TH 22-mediated IL-22 deficiency associated with premature ovarian insufficiency.

    The T(H) 22-mediated IL-22 deficiency associated with premature ovarian insufficiency.
    Zhang W, Xu S, Zhang R, Li Z, Li N, Zhang X, Lu Y, Bian Y, Yang P, Fang F, Qin Y, Jiao X.

    03/15/2023
    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.

    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.
    Briukhovetska D, Suarez-Gosalvez J, Voigt C, Markota A, Giannou AD, Schübel M, Jobst J, Zhang T, Dörr J, Märkl F, Majed L, Müller PJ, May P, Gottschlich A, Tokarew N, Lücke J, Oner A, Schwerdtfeger M, Andreu-Sanz D, Grünmeier R, Seifert M, Michaelides S, Hristov M, König LM, Cadilha BL, Mikhaylov O, Anders HJ, Rothenfusser S, Flavell RA, Cerezo-Wallis D, Tejedo C, Soengas MS, Bald T, Huber S, Endres S, Kobold S., Free PMC Article

    02/11/2023
    Skin colonization of Staphylococcus aureus harboring superantigen toxin genes and its correlation with serum IL-22 level in psoriasis patients.

    Skin colonization of Staphylococcus aureus harboring superantigen toxin genes and its correlation with serum IL-22 level in psoriasis patients.
    Fouad N, Mostafa F, Soltan M, Zaki A, Hassan RA.

    10/15/2022
    Down-regulating Interleukin-22/Interleukin-22 binding protein axis promotes inflammation and aggravates diet-induced metabolic disorders.

    Down-regulating Interleukin-22/Interleukin-22 binding protein axis promotes inflammation and aggravates diet-induced metabolic disorders.
    Gu J, Zhou P, Liu Y, Xu Q, Chen X, Chen M, Lu C, Qu C, Tong Y, Yu Q, Lu X, Yu C, Liu Z.

    10/15/2022
    Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy.

    Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy.
    Pavlidis P, Tsakmaki A, Pantazi E, Li K, Cozzetto D, Digby-Bell J, Yang F, Lo JW, Alberts E, Sa ACC, Niazi U, Friedman J, Long AK, Ding Y, Carey CD, Lamb C, Saqi M, Madgwick M, Gul L, Treveil A, Korcsmaros T, Macdonald TT, Lord GM, Bewick G, Powell N., Free PMC Article

    10/8/2022
    Lack of Association of Polymorphisms in IL22 and IL22RA1 Genes with Fibrosis Severity in Patients with Chronic Hepatitis C.

    Lack of Association of Polymorphisms in IL22 and IL22RA1 Genes with Fibrosis Severity in Patients with Chronic Hepatitis C.
    de Brito RJVC, do Carmo RF, Silva BMS, Barbosa Júnior WL, Vasconcelos LRS, Pereira LMMB, Moura P.

    10/8/2022
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