| Relationship between p16/ki67 immunoscores and PAX1/ZNF582 methylation status in precancerous and cancerous cervical lesions in high-risk HPV-positive women. | Relationship between p16/ki67 immunoscores and PAX1/ZNF582 methylation status in precancerous and cancerous cervical lesions in high-risk HPV-positive women.
Luo H, Lian Y, Tao H, Zhao Y, Wang Z, Zhou J, Zhang Z, Jiang S., Free PMC Article | 09/29/2024 |
| PAX1 represses canonical Wnt signaling pathway and plays dual roles during endoderm differentiation. | PAX1 represses canonical Wnt signaling pathway and plays dual roles during endoderm differentiation.
Miao D, Ren J, Jia Y, Jia Y, Li Y, Huang H, Gao R., Free PMC Article | 04/30/2024 |
| High-grade cervical lesions diagnosed by JAM3/PAX1 methylation in high-risk human papillomavirus-infected patients. | High-grade cervical lesions diagnosed by JAM3/PAX1 methylation in high-risk human papillomavirus-infected patients.
Li X, He S, Zhao X, Sun D, Wu S, Xu D, Li Y., Free PMC Article | 03/11/2024 |
| PAX1 expression in thymic epithelial neoplasms and morphologic mimics. | PAX1 expression in thymic epithelial neoplasms and morphologic mimics.
Parrack PH, Hornick JL, Sholl LM. | 12/15/2023 |
| Aberrant Epigenetic Alteration of PAX1 Expression Contributes to Parathyroid Tumorigenesis. | Aberrant Epigenetic Alteration of PAX1 Expression Contributes to Parathyroid Tumorigenesis.
Singh P, Bhadada SK, Arya AK, Saikia UN, Sachdeva N, Dahiya D, Kaur J, Brandi ML, Rao SD., Free PMC Article | 02/19/2022 |
| Real time quantitative methylation detection of PAX1 gene in cervical cancer screening. | Real time quantitative methylation detection of PAX1 gene in cervical cancer screening.
Liu H, Meng X, Wang J. | 11/13/2021 |
| The application value of PAX1 and ZNF582 gene methylation in high grade intraepithelial lesion and cervical cancer. | The application value of PAX1 and ZNF582 gene methylation in high grade intraepithelial lesion and cervical cancer.
Liang H, Li GL, Liu J, Fu M, Huang H, Zhao K, Wei Y, Xiao J. | 08/28/2021 |
| SOX1 and PAX1 Are Hypermethylated in Cervical Adenocarcinoma and Associated with Better Prognosis. | SOX1 and PAX1 Are Hypermethylated in Cervical Adenocarcinoma and Associated with Better Prognosis.
Zhao Z, Zhang X, Zhao X, Cai J, Wu NY, Wang J., Free PMC Article | 06/12/2021 |
| Hypermethylated PAX1 and ZNF582 genes in the tissue sample are associated with aggressive progression of oral squamous cell carcinoma. | Hypermethylated PAX1 and ZNF582 genes in the tissue sample are associated with aggressive progression of oral squamous cell carcinoma.
Sun R, Juan YC, Su YF, Zhang WB, Yu Y, Yang HY, Yu GY, Peng X. | 12/26/2020 |
| PAX1 is essential for development and function of the human thymus. | PAX1 is essential for development and function of the human thymus.
Yamazaki Y, Urrutia R, Franco LM, Giliani S, Zhang K, Alazami AM, Dobbs AK, Masneri S, Joshi A, Otaizo-Carrasquero F, Myers TG, Ganesan S, Bondioni MP, Ho ML, Marks C, Alajlan H, Mohammed RW, Zou F, Valencia CA, Filipovich AH, Facchetti F, Boisson B, Azzari C, Al-Saud BK, Al-Mousa H, Casanova JL, Abraham RS, Notarangelo LD., Free PMC Article | 12/5/2020 |
| Temporal and spatial expression of Sox9, Pax1, TGF-beta1 and type I and II collagen in human intervertebral disc development. | Temporal and spatial expression of Sox9, Pax1, TGF-β1 and type I and II collagen in human intervertebral disc development.
Xu G, Liu Y, Zhang C, Zhou Y, Hou S, Tang J, Li Z. | 11/21/2020 |
| Paired Box-1 (PAX1) Activates Multiple Phosphatases and Inhibits Kinase Cascades in Cervical Cancer. | Paired Box-1 (PAX1) Activates Multiple Phosphatases and Inhibits Kinase Cascades in Cervical Cancer.
Su PH, Lai HC, Huang RL, Chen LY, Wang YC, Wu TI, Chan MWY, Liao CC, Chen CW, Lin WY, Chang CC., Free PMC Article | 10/24/2020 |
| The methylation levels ofPAX1, SOX1 and ZNF582 genes were all higher in cancer tissues. | Aberrant DNA methylation of PAX1, SOX1 and ZNF582 genes as potential biomarkers for esophageal squamous cell carcinoma.
Tang L, Liou YL, Wan ZR, Tang J, Zhou Y, Zhuang W, Wang G. | 04/11/2020 |
| Data found a strong association between PAX1 methylation and the development of cervical cancer. Hypermethylation of distinct CpG sites may induce HSIL transformation into invasive cervical cancer in both Uyghur and Han patients suggesting the existence of ethnic differences in the genetic susceptibility to cervical cancer. Also, PAX1 methylation and HPV infection exhibited synergistic effects on cervical tumorigenesis. | Association between dense PAX1 promoter methylation and HPV16 infection in cervical squamous epithelial neoplasms of Xin Jiang Uyghur and Han women.
Zhang L, Hu D, Wang S, Zhang Y, Pang L, Tao L, Jia W. | 11/9/2019 |
| Here we report a third family of OTFCS2 phenotype wherein whole exome sequencing identified a novel homozygous small insertion in PAX1 as the underlying genetic cause. | Autosomal recessive otofaciocervical syndrome type 2 with novel homozygous small insertion in PAX1 gene.
Patil SJ, Das Bhowmik A, Bhat V, Satidevi Vineeth V, Vasudevamurthy R, Dalal A. | 05/25/2019 |
| Hypermethylated ZNF582 and PAX1 genes in oral epithelial cells collected by mouth rinse are effective biomarkers for the detection of oral dysplasia and oral cancer. | Hypermethylated ZNF582 and PAX1 genes in mouth rinse samples as biomarkers for oral dysplasia and oral cancer detection.
Cheng SJ, Chang CF, Ko HH, Lee JJ, Chen HM, Wang HJ, Lin HS, Chiang CP. | 05/25/2019 |
| Both PAX1 rs17861031 and rs6137473 were significantly associated with AIS and different PUMC classifications of AIS in a northern Chinese Han population. | Genetic polymorphisms of PAX1 are functionally associated with different PUMC types of adolescent idiopathic scoliosis in a northern Chinese Han population.
Liu G, Liu S, Li X, Chen J, Chen W, Zuo Y, Liu J, Niu Y, Lin M, Zhao S, Long B, Zhao Y, Ye Y, Zhang J, Shen J, Qiu G, Wu Z, Wu N. | 02/9/2019 |
| The association between PAX1 and the susceptibility of AIS was successfully replicated in the Chinese population | Genetic Variant of PAX1 Gene Is Functionally Associated With Adolescent Idiopathic Scoliosis in the Chinese Population.
Xu L, Sheng F, Xia C, Qin X, Tang NL, Qiu Y, Cheng JC, Zhu Z. | 09/29/2018 |
| Hypermethylated ZNF582 and PAX1 genes in the oral scrapings collected from adjacent normal oral mucosal sites rather than cancer sites are associated with aggressive progression and poor prognosis of OSCC | Hypermethylated ZNF582 and PAX1 genes in oral scrapings collected from cancer-adjacent normal oral mucosal sites are associated with aggressive progression and poor prognosis of oral cancer.
Cheng SJ, Chang CF, Ko HH, Liu YC, Peng HH, Wang HJ, Lin HS, Chiang CP. | 08/11/2018 |
| A novel PAX1 null homozygous mutation in autosomal recessive otofaciocervical syndrome associated with severe combined immunodeficiency has been described in a consanguineous family. | A novel PAX1 null homozygous mutation in autosomal recessive otofaciocervical syndrome associated with severe combined immunodeficiency.
Paganini I, Sestini R, Capone GL, Putignano AL, Contini E, Giotti I, Gensini F, Marozza A, Barilaro A, Porfirio B, Papi L. | 07/7/2018 |
| PAX1 gene methylation was associated with the transition of CIN I to CIN II/III and CIN II/III to cervical cancer, so that it could be an auxiliary biomarker to estimate the risk of CIN progress. | PAX1 Methylation as a Potential Biomarker to Predict the Progression of Cervical Intraepithelial Neoplasia: A Meta-analysis of Related Studies.
Luan T, Hua Q, Liu X, Xu P, Gu Y, Qian H, Yan L, Xu X, Geng R, Zeng X, Li P. | 02/10/2018 |
| conclude that hypermethylated ZNF582 and PAX1 are effective biomarkers for the detection of oral dysplasia and oral cancer and for the prediction of oral cancer recurrence | Hypermethylated ZNF582 and PAX1 are effective biomarkers for detection of oral dysplasia and oral cancer.
Cheng SJ, Chang CF, Lee JJ, Chen HM, Wang HJ, Liou YL, Yen C, Chiang CP. | 02/3/2018 |
| DNA methylation status of PAX1 showed a relatively good sensitivity and specificity for the detection of ESOPHAGEAL SQUAMOUS CELL CARCINOMA. | DNA Methylation Status of PAX1 and ZNF582 in Esophageal Squamous Cell Carcinoma.
Huang J, Wang G, Tang J, Zhuang W, Wang LP, Liou YL, Liu YZ, Zhou HH, Zhu YS., Free PMC Article | 07/1/2017 |
| Paired boxed gene 1 protein expression is a potential histopathology biomarker for the differential diagnosis of malignant and premalignant endometrial lesions. Paired boxed gene 1 is also a potential prognostic marker in cases of endometrial carcinoma. | Paired boxed gene 1 expression: A single potential biomarker for differentiating endometrial lesions associated with favorable outcomes in patients with endometrial carcinoma.
Liu LC, Lai HC, Chou YC, Huang RL, Yu MH, Lin CP, Tsai WC, Chiang KJ, Wang YC, Chao TK. | 04/29/2017 |
| Hypermethylation of PAX1 gene may be highly associated with the development of cervical cancer. | Methylation of Cervical Neoplastic Cells Infected With Human Papillomavirus 16.
Ki EY, Lee KH, Hur SY, Rhee JE, Kee MK, Kang C, Park JS., Free PMC Article | 10/8/2016 |