| NRN1 epistasis with BDNF and CACNA1C: mediation effects on symptom severity through neuroanatomical changes in schizophrenia. | NRN1 epistasis with BDNF and CACNA1C: mediation effects on symptom severity through neuroanatomical changes in schizophrenia.
Almodóvar-Payá C, Guardiola-Ripoll M, Giralt-López M, Oscoz-Irurozqui M, Canales-Rodríguez EJ, Madre M, Soler-Vidal J, Ramiro N, Callado LF, Arias B, Gallego C, Pomarol-Clotet E, Fatjó-Vilas M., Free PMC Article | 10/7/2024 |
| NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma. | NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma.
Devitt L, Westphal D, Pieger K, Schneider N, Bosserhoff AK, Kuphal S., Free PMC Article | 05/10/2024 |
| Neuritin affects the activity of neuralized-like 1 by promoting degradation and weakening its affinity for substrate. | Neuritin affects the activity of neuralized-like 1 by promoting degradation and weakening its affinity for substrate.
Zhu J, Li Y, Zhong C, Zhu M, Zheng Y, Xiong A, Meng P, Shan L, Li Y, Huang J., Free PMC Article | 11/28/2023 |
| Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease. | Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease.
Hurst C, Pugh DA, Abreha MH, Duong DM, Dammer EB, Bennett DA, Herskowitz JH, Seyfried NT., Free PMC Article | 05/28/2023 |
| NRN1 Gene as a Potential Marker of Early-Onset Schizophrenia: Evidence from Genetic and Neuroimaging Approaches. | NRN1 Gene as a Potential Marker of Early-Onset Schizophrenia: Evidence from Genetic and Neuroimaging Approaches.
Almodóvar-Payá C, Guardiola-Ripoll M, Giralt-López M, Gallego C, Salgado-Pineda P, Miret S, Salvador R, Muñoz MJ, Lázaro L, Guerrero-Pedraza A, Parellada M, Carrión MI, Cuesta MJ, Maristany T, Sarró S, Fañanás L, Callado LF, Arias B, Pomarol-Clotet E, Fatjó-Vilas M., Free PMC Article | 07/23/2022 |
| NRN1 and CAT Gene Polymorphisms, Complex Noise, and Lifestyles interactively Affect the Risk of Noise-induced Hearing Loss. | NRN1 and CAT Gene Polymorphisms, Complex Noise, and Lifestyles interactively Affect the Risk of Noise-induced Hearing Loss.
Liu SY, Song WQ, Xin JR, Li Z, Lei S, Chen YQ, Zhao TY, Wang HY, Xu LW, Zhang MB, Hong Y, Yang L. | 10/2/2021 |
| Methylation of NRN1 is a novel synthetic lethal marker of PI3K-Akt-mTOR and ATR inhibitors in esophageal cancer. | Methylation of NRN1 is a novel synthetic lethal marker of PI3K-Akt-mTOR and ATR inhibitors in esophageal cancer.
Du W, Gao A, Herman JG, Wang L, Zhang L, Jiao S, Guo M., Free PMC Article | 07/10/2021 |
| The impact of DNA demethylation on the upregulation of the NRN1 and TNFAIP3 genes associated with advanced gastric cancer. | The impact of DNA demethylation on the upregulation of the NRN1 and TNFAIP3 genes associated with advanced gastric cancer.
Wisnieski F, Santos LC, Calcagno DQ, Geraldis JC, Gigek CO, Anauate AC, Chen ES, Rasmussen LT, Payão SLM, Artigiani R, Demachki S, Assumpção PP, Lourenço LG, Arasaki CH, Pabinger S, Krainer J, Leal MF, Burbano RR, Arruda Cardoso Smith M. | 06/12/2021 |
| Association of AEBP1 and NRN1 RNA expression with Alzheimer's disease and neurofibrillary tangle density in middle temporal gyrus. | Association of AEBP1 and NRN1 RNA expression with Alzheimer's disease and neurofibrillary tangle density in middle temporal gyrus.
Piras IS, Krate J, Delvaux E, Nolz J, De Both MD, Mastroeni DF, Serrano GE, Sue LI, Beach TG, Coleman PD, Huentelman MJ. | 10/24/2020 |
| The expression of NRN1 was significantly lower in women with ovarian endometriosis treated with GnRHa. These results suggest that NRN1 may be a biomarker response to the effect of GnRHa treatment for patients with ovarian endometriosis. | Decreased Level of Neurotrophic Factor Neuritin 1 in Women with Ovarian Endometriosis after Receiving Gonadotropin-Releasing Hormone Agonist Treatment.
Rahmawati E, Yang WV, Lei YP, Maurya PK, Chen HW, Tzeng CR., Free PMC Article | 02/1/2020 |
| NRN1 is expressed more extensively in melanoma than in normal melanocytes and healthy tissue. Secreted NRN1 seems to play a role also in earlier phases of melanoma development as we can discover NRN1 over-expression to be associated to primary melanoma | The neurotrophin Neuritin1 (cpg15) is involved in melanoma migration, attachment independent growth, and vascular mimicry.
Bosserhoff AK, Schneider N, Ellmann L, Heinzerling L, Kuphal S., Free PMC Article | 03/10/2018 |
| results suggest that DTNBP1 and NRN1 genes show a joint effect on the risk for schizophrenia spectrum disorders. Although the precise mechanism underlying this effect is unclear, the fact that these genes have been involved in synaptic maturation, connectivity and glutamate signalling suggests that our findings could be of value as a link to the schizophrenia aetiology. | Evidence of an epistatic effect between Dysbindin-1 and Neuritin-1 genes on the risk for schizophrenia spectrum disorders.
Prats C, Arias B, Moya-Higueras J, Pomarol-Clotet E, Parellada M, González-Pinto A, Peralta V, Ibáñez MI, Martín M, Fañanás L, Fatjó-Vilas M. | 12/23/2017 |
| NRN1 is associated with depressive symptoms and executive function in a non-clinical sample. Our results also suggest that the role of NRN1 seems to be modulated by BDNF. | Neurotrophins role in depressive symptoms and executive function performance: Association analysis of NRN1 gene and its interaction with BDNF gene in a non-clinical sample.
Prats C, Arias B, Ortet G, Ibáñez MI, Moya J, Pomarol-Clotet E, Fañanás L, Fatjó-Vilas M. | 12/2/2017 |
| On analysis of the expression of NRN1 in SMA patients for the first time, NRN1 could be a potential modifier gene | Transcript levels of plastin 3 and neuritin 1 modifier genes in spinal muscular atrophy siblings.
Yener İH, Topaloglu H, Erdem-Özdamar S, Dayangac-Erden D. | 05/13/2017 |
| Ca(2+)/calcineurin (CaN)/nuclear factor of activated T-cells (NFAT) c4 axis is required for neuritin-induced Kv4.2 transcriptional expression and potentiation of IA densities in cerebellum granule neurons. | Neuritin Up-regulates Kv4.2 α-Subunit of Potassium Channel Expression and Affects Neuronal Excitability by Regulating the Calcium-Calcineurin-NFATc4 Signaling Pathway.
Yao JJ, Zhao QR, Liu DD, Chow CW, Mei YA., Free PMC Article | 05/7/2017 |
| (i) NRN1 variability is a shared risk factor for both schizophrenia-spectrum disorders (SSD) and bipolar disorders (BPD), (ii) NRN1 may have a selective impact on age at onset and intelligence in SSD. | Involvement of NRN1 gene in schizophrenia-spectrum and bipolar disorders and its impact on age at onset and cognitive functioning.
Fatjó-Vilas M, Prats C, Pomarol-Clotet E, Lázaro L, Moreno C, González-Ortega I, Lera-Miguel S, Miret S, Muñoz MJ, Ibáñez I, Campanera S, Giralt-López M, Cuesta MJ, Peralta V, Ortet G, Parellada M, González-Pinto A, McKenna PJ, Fañanás L. | 10/29/2016 |
| Data indicate that neuritin not only plays an important role in the nervous system but also has an effect on the migration, senescence, proliferation, and viability of stem cells | Effects of neuritin on the migration, senescence and proliferation of human bone marrow mesenchymal stem cells.
Wang X, Liu C, Xu F, Cui L, Tan S, Chen R, Yang L, Huang J. | 04/30/2016 |
| Neuritin is reduced in the brains of Alzheimer's disease (AD) patients. | Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease.
Choi Y, Lee K, Ryu J, Kim HG, Jeong AY, Woo RS, Lee JH, Hyun JW, Hahn S, Kim JH, Kim HS., Free PMC Article | 04/25/2015 |
| MiR-204 promotes apoptosis in oxidative stress-induced rat Schwann cells by suppressing neuritin expression | MiR-204 promotes apoptosis in oxidative stress-induced rat Schwann cells by suppressing neuritin expression.
Gao R, Wang L, Sun J, Nie K, Jian H, Gao L, Liao X, Zhang H, Huang J, Gan S. | 10/18/2014 |
| we found neuritin is overexpressed in astrocytoma, which may be an important factor in tumorigenesis and progression of astrocytoma | Neuritin expression and its relation with proliferation, apoptosis, and angiogenesis in human astrocytoma.
Zhang L, Zhao Y, Wang CG, Fei Z, Wang Y, Li L, Li L, Zhen HN. | 01/21/2012 |
| Data show that SMN and HuD form a complex in spinal motor axons, and that both interact with cpg15 mRNA in neurons. | Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits.
Akten B, Kye MJ, Hao le T, Wertz MH, Singh S, Nie D, Huang J, Merianda TT, Twiss JL, Beattie CE, Steen JA, Sahin M., Free PMC Article | 10/1/2011 |
| NRN1 polymorphisms have roles in fluid intelligence in schizophrenia | Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia.
Chandler D, Dragović M, Cooper M, Badcock JC, Mullin BH, Faulkner D, Wilson SG, Hallmayer J, Howell S, Rock D, Palmer LJ, Kalaydjieva L, Jablensky A. | 01/1/2011 |
| CPG15 and CPG15-2 perform similar cellular functions but may play distinct roles in vivo through their cell-type- and tissue-specific transcriptional regulation | cpg15 and cpg15-2 constitute a family of activity-regulated ligands expressed differentially in the nervous system to promote neurite growth and neuronal survival.
Fujino T, Wu Z, Lin WC, Phillips MA, Nedivi E., Free PMC Article | 01/21/2010 |
| By Northern blot, we confirm hypoxia-induced expression of insulin-like growth factor binding protein 3 (igfbp3), thioredoxin-interacting protein (txnip), neuritin (nrn1). | Characterization of the expression of the hypoxia-induced genes neuritin, TXNIP and IGFBP3 in cancer.
Le Jan S, Le Meur N, Cazes A, Philippe J, Le Cunff M, Léger J, Corvol P, Germain S. | 01/21/2010 |