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    SIRT7 sirtuin 7 [ Homo sapiens (human) ]

    Gene ID: 51547, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    [Effect of SIRT7 on inhibiting the epithelial-mesenchymal transformation in pancreatic cancer cells and related mechanism].

    [Effect of SIRT7 on inhibiting the epithelial-mesenchymal transformation in pancreatic cancer cells and related mechanism].
    Wang MD, Gao TY, Huang W, Yang YK, Wang Y.

    10/10/2024
    Sirt7/HIC1 complex participates in hyperglycaemia-mediated EndMT via modulation of SDC1 expression in diabetic kidney disease and metabolic memory.

    Sirt7/HIC1 complex participates in hyperglycaemia-mediated EndMT via modulation of SDC1 expression in diabetic kidney disease and metabolic memory.
    Lu L, Zhu M, Wu Q, Sun Z, Chen X, Miao C., Free PMC Article

    08/1/2024
    SIRT7 promotes mitochondrial biogenesis to render the adaptive resistance to MAPK inhibition in melanoma.

    SIRT7 promotes mitochondrial biogenesis to render the adaptive resistance to MAPK inhibition in melanoma.
    Du J, Yi X, Guo S, Wang H, Shi Q, Zhang J, Tian Y, Wang H, Zhang H, Zhang B, Gao T, Li C, Guo W, Yang Y.

    07/16/2024
    SIRT7 promotes lung cancer progression by destabilizing the tumor suppressor ARF.

    SIRT7 promotes lung cancer progression by destabilizing the tumor suppressor ARF.
    Kumari P, Tarighi S, Fuchshuber E, Li L, Fernández-Duran I, Wang M, Ayoson J, Castelló-García JM, Gámez-García A, Espinosa-Alcantud M, Sreenivasan K, Guenther S, Olivella M, Savai R, Yue S, Vaquero A, Braun T, Ianni A., Free PMC Article

    06/26/2024
    SIRT7: A potential prognostic marker and therapeutic target in gallbladder cancer.

    SIRT7: A potential prognostic marker and therapeutic target in gallbladder cancer.
    Xu B, Cai X, Cai G, Huang G.

    04/18/2024
    KAT8/SIRT7-mediated Fascin-K41 acetylation/deacetylation regulates tumor metastasis in esophageal squamous cell carcinoma.

    KAT8/SIRT7-mediated Fascin-K41 acetylation/deacetylation regulates tumor metastasis in esophageal squamous cell carcinoma.
    Li DJ, Cheng YW, Pan JM, Guo ZC, Wang SH, Huang QF, Nie PJ, Shi WQ, Xu XE, Wen B, Zhong JL, Zhang ZD, Wu ZY, Zhao H, Liao LD, Wu JY, Zhang K, Dong G, Li EM, Xu LY.

    04/5/2024
    Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krupple-like factor 4 deacetylation.

    Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation.
    Zhang J, Xu C, Tang X, Sun S, Liu S, Yang L, Chen Y, Yang Q, Wei TW, Wu X, Wang J, Wang C, Yan X, Yang L, Niu Y, Gou D, Shyy JYJ, Liu B., Free PMC Article

    04/3/2024
    SIRT7 promotes the proliferation and migration of anaplastic thyroid cancer cells by regulating the desuccinylation of KIF23.

    SIRT7 promotes the proliferation and migration of anaplastic thyroid cancer cells by regulating the desuccinylation of KIF23.
    Wu Y, Chen W, Miao H, Xu T., Free PMC Article

    02/23/2024
    USP39 interacts with SIRT7 to promote cervical squamous cell carcinoma by modulating autophagy and oxidative stress via FOXM1.

    USP39 interacts with SIRT7 to promote cervical squamous cell carcinoma by modulating autophagy and oxidative stress via FOXM1.
    Yu J, Yuan S, Song J, Yu S., Free PMC Article

    11/29/2023
    SIRT7: the seventh key to unlocking the mystery of aging.

    SIRT7: the seventh key to unlocking the mystery of aging.
    Raza U, Tang X, Liu Z, Liu B., Free PMC Article

    11/27/2023
    MiR-21-5p promotes sorafenib resistance and hepatocellular carcinoma progression by regulating SIRT7 ubiquitination through USP24.

    MiR-21-5p promotes sorafenib resistance and hepatocellular carcinoma progression by regulating SIRT7 ubiquitination through USP24.
    Hu Z, Zhao Y, Mang Y, Zhu J, Yu L, Li L, Ran J.

    06/1/2023
    Musclin attenuates lipid deposition in hepatocytes through SIRT7/autophagy-mediated suppression of ER stress.

    Musclin attenuates lipid deposition in hepatocytes through SIRT7/autophagy-mediated suppression of ER stress.
    Cho W, Choi SW, Oh H, Baygutalp F, Abd El-Aty AM, Jeong JH, Song JH, Shin YK, Jung TW.

    04/21/2023
    A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.

    A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.
    Wang X, Jiang X, Li B, Zheng J, Guo J, Gao L, Du M, Weng X, Li L, Chen S, Zhang J, Fang L, Liu T, Wang L, Liu W, Neculai D, Sun Q., Free PMC Article

    04/14/2023
    Oncogenic SIRT7 inhibits GATA4 transcriptional activity and activates the Wnt signaling pathway in ovarian cancer.

    Oncogenic SIRT7 inhibits GATA4 transcriptional activity and activates the Wnt signaling pathway in ovarian cancer.
    Li G, Xu W, Li X, Chen M, Shi Y, Wei M, Peng D.

    03/29/2023
    SIRT7 orchestrates melanoma progression by simultaneously promoting cell survival and immune evasion via UPR activation.

    SIRT7 orchestrates melanoma progression by simultaneously promoting cell survival and immune evasion via UPR activation.
    Yi X, Wang H, Yang Y, Wang H, Zhang H, Guo S, Chen J, Du J, Tian Y, Ma J, Zhang B, Wu L, Shi Q, Gao T, Guo W, Li C., Free PMC Article

    03/20/2023
    SIRT7 silencing by miR-152-3p confers cell apoptosis and renal functional impairment induced by renal ischaemia/reperfusion injury.

    SIRT7 silencing by miR-152-3p confers cell apoptosis and renal functional impairment induced by renal ischaemia/reperfusion injury.
    Wang Y, Wu XQ, Cai JR, Ji HX, Xu T.

    02/11/2023
    CYP2E1-dependent upregulation of SIRT7 is response to alcohol mediated metastasis in hepatocellular carcinoma.

    CYP2E1-dependent upregulation of SIRT7 is response to alcohol mediated metastasis in hepatocellular carcinoma.
    Zhang C, Zhao J, Zhao J, Liu B, Tang W, Liu Y, Huang W, Weinman SA, Li Z., Free PMC Article

    12/24/2022
    USP17L2-SIRT7 axis regulates DNA damage repair and chemoresistance in breast cancer cells.

    USP17L2-SIRT7 axis regulates DNA damage repair and chemoresistance in breast cancer cells.
    Su Y, Wu C, Chang Y, Li L, Chen Y, Jia X, Wang X, Lv Y, Yu B, Yuan J.

    10/15/2022
    PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours.

    PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours.
    Yuan HF, Zhao M, Zhao LN, Yun HL, Yang G, Geng Y, Wang YF, Zheng W, Yuan Y, Song TQ, Niu JQ, Zhang XD., Free PMC Article

    09/10/2022
    SIRT7 Deficiency Protects against Abeta42-Induced Apoptosis through the Regulation of NOX4-Derived Reactive Oxygen Species Production in SH-SY5Y Cells.

    SIRT7 Deficiency Protects against Aβ(42)-Induced Apoptosis through the Regulation of NOX4-Derived Reactive Oxygen Species Production in SH-SY5Y Cells.
    Mizutani H, Sato Y, Yamazaki M, Yoshizawa T, Ando Y, Ueda M, Yamagata K., Free PMC Article

    09/3/2022
    A miR-125/Sirtuin-7 pathway drives the pro-calcific potential of myeloid cells in diabetic vascular disease.

    A miR-125/Sirtuin-7 pathway drives the pro-calcific potential of myeloid cells in diabetic vascular disease.
    Vigili de Kreutzenberg S, Giannella A, Ceolotto G, Faggin E, Cappellari R, Mazzucato M, Fraccaro C, Tarantini G, Avogaro A, Fadini GP., Free PMC Article

    08/13/2022
    Downregulation of LINC00886 facilitates epithelial-mesenchymal transition through SIRT7/ELF3/miR-144 pathway in esophageal squamous cell carcinoma.

    Downregulation of LINC00886 facilitates epithelial-mesenchymal transition through SIRT7/ELF3/miR-144 pathway in esophageal squamous cell carcinoma.
    Dong Z, Yang L, Lu J, Guo Y, Shen S, Liang J, Guo W.

    08/6/2022
    Sirt7 associates with ELK1 to participate in hyperglycemia memory and diabetic nephropathy via modulation of DAPK3 expression and endothelial inflammation.

    Sirt7 associates with ELK1 to participate in hyperglycemia memory and diabetic nephropathy via modulation of DAPK3 expression and endothelial inflammation.
    Li X, Liu J, Lu L, Huang T, Hou W, Wang F, Yu L, Wu F, Qi J, Chen X, Meng Z, Zhu M.

    07/23/2022
    The Role of Pentraxin-3, Fetuin-A and Sirtuin-7 in the Diagnosis of Prostate Cancer.

    The Role of Pentraxin-3, Fetuin-A and Sirtuin-7 in the Diagnosis of Prostate Cancer.
    Güzel Ö, Kösem A, Aslan Y, Asfuroglu A, Balci M, Senel C, Tuncel A.

    06/18/2022
    SIRT7 interacts with TEK (TIE2) to promote adriamycin induced metastasis in breast cancer.

    SIRT7 interacts with TEK (TIE2) to promote adriamycin induced metastasis in breast cancer.
    Yang F, Hu Y, Shao L, Zhuang J, Huo Q, He S, Chen S, Wang J, Xie N.

    03/19/2022
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