| Medium and large alleles of the PGC gene are risk factors for gastric cancer. | Medium and large alleles of the PGC gene are risk factors for gastric cancer.
Sánchez-López JY, Vázquez-Ibarra KC, García-Muro AM, García-Ruvalcaba A, Pacheco-Sotelo S, Díaz-Herrera LC, Marin-Contreras ME. | 04/14/2023 |
| Pepsinogen II in gastritis and Helicobacter pylori infection. | Pepsinogen II in gastritis and Helicobacter pylori infection.
Di Mario F, Crafa P, Barchi A, Franzoni L, Franceschi M, Russo M, Bricca L, Brozzi L, Rodriguez Castro K, Rugge M. | 03/19/2022 |
| Diagnostic value of MRI-DWI signal intensity value combined with serum PGI, PGII and CA199 in early gastric cancer. | Diagnostic value of MRI-DWI signal intensity value combined with serum PGI, PGII and CA199 in early gastric cancer.
Li M, Zheng G, Yu L, Tan LL, Li X, Li MJ, Li C, Li S, Liang J, Zhong Z, Li ZM. | 03/12/2022 |
| Pepsinogen C expression-related lncRNA/circRNA/mRNA profile and its co-mediated ceRNA network in gastric cancer. | Pepsinogen C expression-related lncRNA/circRNA/mRNA profile and its co-mediated ceRNA network in gastric cancer.
Yan LR, Ding HX, Shen SX, Lu XD, Yuan Y, Xu Q. | 01/1/2022 |
| Clinical correlation between serum pepsinogen level and gastric atrophy in gastric neoplasm. | Clinical correlation between serum pepsinogen level and gastric atrophy in gastric neoplasm.
Cha JH, Jang JS., Free PMC Article | 05/29/2021 |
| Association between serum pepsinogen and atherosclerotic cardiovascular disease. | Association between serum pepsinogen and atherosclerotic cardiovascular disease.
Gao X, Jia Y, Xu H, Li Y, Zhu Q, Wei C, Hou J, Li D, Wang W, Li Z, Guo R, Jia J, Wu Y, Wei Z, Qi X, Li Y. | 03/6/2021 |
| Diagnostic value of serum pepsinogen I, pepsinogen II, and gastrin-17 levels for population-based screening for early-stage gastric cancer. | Diagnostic value of serum pepsinogen I, pepsinogen II, and gastrin-17 levels for population-based screening for early-stage gastric cancer.
Wang Y, Zhu Z, Liu Z, Zhao Z, Xue X, Li X, Li P, Rong G, Ma Y., Free PMC Article | 01/9/2021 |
| the pepsinogen I/II ratio was the most reliable gastric mucosal-change biomarker. | Serum pepsinogens as a gastric cancer and gastritis biomarker in South and Southeast Asian populations.
Miftahussurur M, Waskito LA, Aftab H, Vilaichone RK, Subsomwong P, Nusi IA, Syam AF, Ratanachu-Ek T, Doohan D, Siregar G, Rezkitha YAA, Fauzia KA, Mahachai V, Yamaoka Y., Free PMC Article | 07/4/2020 |
| Study found 15 pairwise PGC-lncRNAs SNPs had interactions: five pairs were associated with atrophic gastritis (AG) risk, and ten pairs were associated with gastric cancer (GC) risk. Several combinations showed obvious epistasis and cumulative effects on disease risk for AG and GC. | SNP interactions of PGC with its neighbor lncRNAs enhance the susceptibility to gastric cancer/atrophic gastritis and influence the expression of involved molecules.
Lv Z, Sun L, Xu Q, Gong Y, Jing J, Dong N, Xing C, Yuan Y., Free PMC Article | 12/21/2019 |
| Recombinant pepsin C and pepsinogen C were purified from transgenic rice culture medium, and the NH2-terminal 5-residue sequences were verified by amino acid sequencing. | Spontaneous pepsin C-catalyzed activation of human pepsinogen C in transgenic rice cell suspension culture: Production and characterization of human pepsin C.
Islam MR, Kim NS, Jung JW, Kim HB, Han SC, Yang MS. | 07/21/2018 |
| serum levels correlated with age, sex and the level of Helicobacter pylori infection | Serum Pepsinogen Levels Are Correlated With Age, Sex and the Level of Helicobacter pylori Infection in Healthy Individuals.
Huang RG, Xiao HL, Zhou B, Song XH, Zhang J, Wang CM, Jiang YH, Chen DZ, Huang B. | 05/20/2017 |
| Pepsinogen-II 100 bp ins/del gene polymorphism and its elevated circulating levels are associated with gastric cancer, particularly with Helicobacter pylori infection and intestinal metaplasia. | Pepsinogen-II 100 bp ins/del gene polymorphism and its elevated circulating levels are associated with gastric cancer, particularly with Helicobacter pylori infection and intestinal metaplasia.
Kumar S, Kumari N, Mittal RD, Ghoshal UC. | 04/8/2017 |
| Results suggest that rs9471643 CG and rs6458238 AG/AA genotypes have important roles in up-regulating PGC expression, which may partially explain why individuals with these favorable genotypes have decreased risks of getting gastric cancer. | Polymorphic rs9471643 and rs6458238 upregulate PGC transcription and protein expression in overdominant or dominant models.
He C, Xu Q, Tu H, Sun L, Gong Y, Liu J, Yuan Y. | 09/10/2016 |
| Data show that SNP interactions among H. pylori-related genes PGC, PTPN11, and IL1B, are associated with susceptibility to gastric carcinogenesis. | SNP interactions of Helicobacter pylori-related host genes PGC, PTPN11, IL1B, and TLR4 in susceptibility to gastric carcinogenesis.
He C, Tu H, Sun L, Xu Q, Gong Y, Jing J, Dong N, Yuan Y., Free PMC Article | 07/2/2016 |
| The results highlight an important role of PGC rs3789210 and rs6939861 in altering susceptibility to atrophic gastritis and/or gastric cancer. | PGC TagSNP and its interaction with H. pylori and relation with gene expression in susceptibility to gastric carcinogenesis.
He CY, Sun LP, Xu Q, Liu JW, Jiang JY, Dong NN, Yuan Y., Free PMC Article | 10/3/2015 |
| Pepsinogen II is a good marker of corpus morphological changes before and after H. pylori eradication. | Pepsinogen II can be a potential surrogate marker of morphological changes in corpus before and after H. pylori eradication.
Massarrat S, Haj-Sheykholeslami A, Mohamadkhani A, Zendehdel N, Aliasgari A, Rakhshani N, Stolte M, Shahidi SM., Free PMC Article | 03/21/2015 |
| High serum Pepsinogen II level is associ9ated with the progression of gastric precancerous lesions. | Temporal changes in serum biomarkers and risk for progression of gastric precancerous lesions: a longitudinal study.
Tu H, Sun L, Dong X, Gong Y, Xu Q, Jing J, Long Q, Flanders WD, Bostick RM, Yuan Y., Free PMC Article | 01/10/2015 |
| An interaction effect of pri-let-7a-1 rs10739971 polymorphism with ERCC6 rs1917799 polymorphism was observed for the risk of gastric cancer. | The interaction effects of pri-let-7a-1 rs10739971 with PGC and ERCC6 gene polymorphisms in gastric cancer and atrophic gastritis.
Xu Q, Liu JW, He CY, Sun LP, Gong YH, Jing JJ, Xing CZ, Yuan Y., Free PMC Article | 12/27/2014 |
| Pepsin and pepsinogen in middle ear effusion are probably caused by LPR and may be involved in the pathogenesis of OME. | Role of pepsin and pepsinogen: linking laryngopharyngeal reflux with otitis media with effusion in children.
Luo HN, Yang QM, Sheng Y, Wang ZH, Zhang Q, Yan J, Hou J, Zhu K, Cheng Y, Wang BT, Xu YL, Zhang XH, Ren XY, Xu M. | 08/23/2014 |
| plasma PG II level significantly correlated with H. pylori-infected gastric cancer | Serum pepsinogen II is a better diagnostic marker in gastric cancer.
Cao XY, Jia ZF, Jin MS, Cao DH, Kong F, Suo J, Jiang J., Free PMC Article | 03/8/2014 |
| High serum pepsinogen II is associated with gastric cancer development and activity of Helicobacter pylori-associated chronic gastritis. | Cancer development based on chronic active gastritis and resulting gastric atrophy as assessed by serum levels of pepsinogen and Helicobacter pylori antibody titer.
Yoshida T, Kato J, Inoue I, Yoshimura N, Deguchi H, Mukoubayashi C, Oka M, Watanabe M, Enomoto S, Niwa T, Maekita T, Iguchi M, Tamai H, Utsunomiya H, Yamamichi N, Fujishiro M, Iwane M, Takeshita T, Ushijima T, Ichinose M. | 03/1/2014 |
| Levels of pepsinogen/pepsin A and C are higher in the mouth swabs of infants with clinical gastroesophageal reflux. | Detection of pepsin in mouth swab: correlation with clinical gastroesophageal reflux in preterm infants.
Farhath S, He Z, Saslow J, Soundar S, Amendolia B, Bhat V, Pyon K, Stahl G, Mehta D, Aghai ZH. | 02/1/2014 |
| PGC rs6458238, PGC rs4711690 and PTPN11 rs12229892 were associated with susceptibilities to atrophic gastritis and/or gastric cancer. | Helicobacter pylori-related host gene polymorphisms associated with susceptibility of gastric carcinogenesis: a two-stage case-control study in Chinese.
He C, Tu H, Sun L, Xu Q, Li P, Gong Y, Dong N, Yuan Y. | 09/7/2013 |
| Data suggest that serum pepsinogen I/II ratio (pepsinogen A/C ratio) is correlated with diabetic nephropathy and thus may be a biological marker for degree of urinary albumin excretion in patients with type 2 diabetes. | Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.
Senmaru T, Fukui M, Kuroda M, Tanaka M, Ushigome E, Sakabe K, Nakanishi N, Mineoka Y, Asano M, Yamazaki M, Hasegawa G, Nakamura N. | 08/31/2013 |
| The serum levels of PG II and G-17 were significantly higher in Changle than those in Fuan. | Serum pepsinogens, gastrin-17 and Helicobacter pylori antibody in the residents of two cities in china with distinct mortality rates of gastric cancer.
Zheng KC, Aoki K, Li XQ, Lin SG, Wu BS, Zhong WL, Chen TH, Lin S, You JW, Su C. | 08/10/2013 |