| SARS-CoV-2 Accessory Protein ORF8 Targets the Dimeric IgA Receptor pIgR. | SARS-CoV-2 Accessory Protein ORF8 Targets the Dimeric IgA Receptor pIgR.
Laprise F, Arduini A, Duguay M, Pan Q, Liang C., Free PMC Article | 08/13/2024 |
| Polymeric immunoglobulin receptor (pIgR) in cancer. | Polymeric immunoglobulin receptor (pIgR) in cancer.
Chae J, Choi J, Chung J. | 11/29/2023 |
| Expression of polymeric immunoglobulin receptor (PIGR) and the effect of PIGR overexpression on breast cancer cells. | Expression of polymeric immunoglobulin receptor (PIGR) and the effect of PIGR overexpression on breast cancer cells.
Asanprakit W, Lobo DN, Eremin O, Bennett AJ., Free PMC Article | 10/5/2023 |
| Polymeric immunoglobulin receptor and galectin-3-binding protein are raised in biliary atresia: Reveals a proteomic-based study. | Polymeric immunoglobulin receptor and galectin-3-binding protein are raised in biliary atresia: Reveals a proteomic-based study.
Ram AK, Kanojia RP, Bhatia A, Menon P, Minz RW, Dhawan V, Arora A, Kumar Y. | 09/19/2023 |
| Hepatic pIgR-mediated secretion of IgA limits bacterial translocation and prevents ethanol-induced liver disease in mice. | Hepatic pIgR-mediated secretion of IgA limits bacterial translocation and prevents ethanol-induced liver disease in mice.
Hendrikx T, Lang S, Rajcic D, Wang Y, McArdle S, Kim K, Mikulski Z, Schnabl B., Free PMC Article | 09/15/2023 |
| M1 macrophages evoke an increase in polymeric immunoglobulin receptor (PIGR) expression in MDA-MB468 breast cancer cells through secretion of interleukin-1beta. | M1 macrophages evoke an increase in polymeric immunoglobulin receptor (PIGR) expression in MDA-MB468 breast cancer cells through secretion of interleukin-1β.
Asanprakit W, Lobo DN, Eremin O, Bennett AJ., Free PMC Article | 10/15/2022 |
| Patient pIgR-enriched extracellular vesicles drive cancer stemness, tumorigenesis and metastasis in hepatocellular carcinoma. | Patient pIgR-enriched extracellular vesicles drive cancer stemness, tumorigenesis and metastasis in hepatocellular carcinoma.
Tey SK, Wong SWK, Chan JYT, Mao X, Ng TH, Yeung CLS, Leung Z, Fung HL, Tang AHN, Wong DKH, Mak LY, Yuen MF, Sin CF, Ng IO, Ma SKY, Lee TKW, Cao P, Zhong K, Gao Y, Yun JP, Yam JWP. | 04/30/2022 |
| Polymeric immunoglobulin receptor (PIGR) exerts oncogenic functions via activating ribosome pathway in hepatocellular carcinoma. | Polymeric immunoglobulin receptor (PIGR) exerts oncogenic functions via activating ribosome pathway in hepatocellular carcinoma.
Zhang Y, Zhang J, Chen X, Yang Z., Free PMC Article | 09/18/2021 |
| A Bioinformatic Analysis of Correlations between Polymeric Immunoglobulin Receptor (PIGR) and Liver Fibrosis Progression. | A Bioinformatic Analysis of Correlations between Polymeric Immunoglobulin Receptor (PIGR) and Liver Fibrosis Progression.
Zhang Y, Lu W, Chen X, Cao Y, Yang Z., Free PMC Article | 05/29/2021 |
| High expression levels of polymeric immunoglobulin receptor are correlated with chemoresistance and poor prognosis in pancreatic cancer. | High expression levels of polymeric immunoglobulin receptor are correlated with chemoresistance and poor prognosis in pancreatic cancer.
Ohkuma R, Yada E, Ishikawa S, Komura D, Kubota Y, Hamada K, Horiike A, Ishiguro T, Hirasawa Y, Ariizumi H, Shida M, Watanabe M, Onoue R, Ando K, Tsurutani J, Yoshimura K, Sasada T, Aoki T, Murakami M, Norose T, Ohike N, Takimoto M, Kobayashi S, Tsunoda T, Wada S., Free PMC Article | 03/13/2021 |
| Associations of urinary polymeric immunoglobulin receptor peptides in the context of cardio-renal syndrome. | Associations of urinary polymeric immunoglobulin receptor peptides in the context of cardio-renal syndrome.
He T, Siwy J, Metzger J, Mullen W, Mischak H, Schanstra JP, Zürbig P, Jankowski V., Free PMC Article | 12/5/2020 |
| High PIGR expression is associated with kidney diseases. | Localization and Regulation of Polymeric Ig Receptor in Healthy and Diseased Human Kidney.
Krawczyk KM, Nilsson H, Nyström J, Lindgren D, Leandersson K, Swärd K, Johansson ME. | 03/28/2020 |
| Data provide evidence that pIgR protein is targeted directly by Slp protein contributing to E. coli adherence. | The Escherichia coli O157:H7 carbon starvation-inducible lipoprotein Slp contributes to initial adherence in vitro via the human polymeric immunoglobulin receptor.
Fedorchuk C, Kudva IT, Kariyawasam S., Free PMC Article | 02/8/2020 |
| We identified two SLN genes (PIGR and TFAP2A) that provided high prognostic accuracy in SLN-positive melanoma patients (AUC = 0.864). These two SLN genes, along with clinicopathological features, can differentiate the high- and low-risk groups in node-positive melanoma patients. | Sentinel Lymph Node Genes to Predict Prognosis in Node-Positive Melanoma Patients.
Hao H, Xiao D, Pan J, Qu J, Egger M, Waigel S, Sanders MA, Zacharias W, Rai SN, McMasters KM. | 02/3/2018 |
| pIgR may be involved in pancreatic ductal adenocarcinoma progression and may be linked stromal activity. Further work on its precise role is mandated in in vivo models, to understand its influence on cancer progression. | Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma.
Arumugam P, Bhattacharya S, Chin-Aleong J, Capasso M, Kocher HM. | 10/7/2017 |
| RrgA, binds both polymeric immunoglobulin receptor (pIgR) and PECAM-1, whereas the choline binding protein PspC binds, but to a lower extent, only pIgR | pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion.
Iovino F, Engelen-Lee JY, Brouwer M, van de Beek D, van der Ende A, Valls Seron M, Mellroth P, Muschiol S, Bergstrand J, Widengren J, Henriques-Normark B., Free PMC Article | 09/23/2017 |
| A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic pollution. | A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic.
Ward-Caviness CK, Neas LM, Blach C, Haynes CS, LaRocque-Abramson K, Grass E, Dowdy ZE, Devlin RB, Diaz-Sanchez D, Cascio WE, Miranda ML, Gregory SG, Shah SH, Kraus WE, Hauser ER., Free PMC Article | 09/2/2017 |
| The polymeric immunoglobulin receptor secretory component structure comprises five immunoglobulin-like domains (D1-D5) arranged as a triangle, with an interface between ligand-binding domains D1 and D5. | The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins.
Stadtmueller BM, Huey-Tubman KE, López CJ, Yang Z, Hubbell WL, Bjorkman PJ., Free PMC Article | 11/12/2016 |
| Reduced expression of the polymeric immunoglobulin receptor in pancreatic and periampullary adenocarcinoma signifies tumour progression and poor prognosis. | Reduced expression of the polymeric immunoglobulin receptor in pancreatic and periampullary adenocarcinoma signifies tumour progression and poor prognosis.
Fristedt R, Elebro J, Gaber A, Jonsson L, Heby M, Yudina Y, Nodin B, Uhlén M, Eberhard J, Jirström K., Free PMC Article | 01/2/2016 |
| Crohn disease patients were characterized as having decreased median expression of PIGR, in non-inflamed colonic mucosa. By contrast, Ulcerative colitis patients exhibited decreased expression of PIGR in colon mucosa. | Correlation of Biomarker Expression in Colonic Mucosa with Disease Phenotype in Crohn's Disease and Ulcerative Colitis.
Bruno ME, Rogier EW, Arsenescu RI, Flomenhoft DR, Kurkjian CJ, Ellis GI, Kaetzel CS., Free PMC Article | 12/19/2015 |
| These results demonstrate that SLPI down-regulates pIgR expression through the NF-kappaB signaling pathway by inhibiting degradation of IkappaBbeta protein. | Secretory leukocyte protease inhibitor inhibits expression of polymeric immunoglobulin receptor via the NF-κB signaling pathway.
Mikami Y, Iwase T, Komiyama Y, Matsumoto N, Oki H, Komiyama K. | 12/19/2015 |
| Report PIGR expression in human fallopian tubes, primary epithelial ovarian tumours and metastases. | Expression and prognostic significance of the polymeric immunoglobulin receptor in epithelial ovarian cancer.
Berntsson J, Lundgren S, Nodin B, Uhlén M, Gaber A, Jirström K., Free PMC Article | 10/31/2015 |
| the polymeric immunoglobulin receptor (pIgR) is highly expressed by renal cyst-lining cells. pIgR expression is, in part, driven by aberrant STAT6 pathway activation. | Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney Disease.
Olsan EE, Matsushita T, Rezaei M, Weimbs T., Free PMC Article | 08/29/2015 |
| Positive expression of pIgR was statistically significantly associated with poor prognosis of patients with colon carcinoma hepatic metastasis. | COLORECTAL Polymeric Immunoglobulin Receptor Expression is Correlated with Hepatic Metastasis and Poor Prognosis in Colon Carcinoma Patients with Hepatic Metastasis.
Liu F, Ye P, Bi T, Teng L, Xiang C, Wang H, Li Y, Jin K, Mou X. | 08/15/2015 |
| In conclusion these data suggest that Streptococcus pneumoniae PspC-promoted uptake via the polymeric immunoglobulin receptor of epithelial cells is mediated by both clathrin and caveolin dependent pathway. | Endocytosis of Streptococcus pneumoniae via the polymeric immunoglobulin receptor of epithelial cells relies on clathrin and caveolin dependent mechanisms.
Asmat TM, Agarwal V, Saleh M, Hammerschmidt S. | 07/25/2015 |