| Conformational alteration in glycan induces phospholipase Cbeta1 activation and angiogenesis. | Conformational alteration in glycan induces phospholipase Cβ1 activation and angiogenesis.
Wang SH, Cheng JY, Tsai HH, Lo TC, Hung JT, Lin CC, Lee CW, Ho YH, Kuo HH, Yu AL, Yu J., Free PMC Article | 01/11/2023 |
| Selective role of the translin/trax RNase complex in hippocampal synaptic plasticity. | Selective role of the translin/trax RNase complex in hippocampal synaptic plasticity.
Park AJ, Shetty MS, Baraban JM, Abel T., Free PMC Article | 08/7/2021 |
| Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion. | Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion.
Fu X, Shah AP, Li Z, Li M, Tamashiro KL, Baraban JM., Free PMC Article | 07/10/2021 |
| Deletion of the TN/TX complex selectively increases aortic miR-181b and prevents increased vascular stiffness caused by ingestion of high-salt water. | Deletion of the microRNA-degrading nuclease, translin/trax, prevents pathogenic vascular stiffness.
Tuday E, Nomura Y, Ruhela D, Nakano M, Fu X, Shah A, Roman B, Yamaguchi A, An SS, Steenbergen C, Baraban JM, Berkowitz DE, Das S., Free PMC Article | 04/11/2020 |
| Thus, the authors define a new memory mechanism by which learning reverses microRNA-mediated silencing of the novel plasticity protein ACVR1C via translin/trax. | Learning induces the translin/trax RNase complex to express activin receptors for persistent memory.
Park AJ, Havekes R, Fu X, Hansen R, Tudor JC, Peixoto L, Li Z, Wu YC, Poplawski SG, Baraban JM, Abel T., Free PMC Article | 05/19/2018 |
| TRAX is required for DNA repair, by interacting with activated ATM and protects cells from genotoxic stress-induced apoptosis. | A central role of TRAX in the ATM-mediated DNA repair.
Wang JY, Chen SY, Sun CN, Chien T, Chern Y. | 09/3/2016 |
| trax acts to regulate translin's RNA and DNA binding affinities as part of a cellular RNA trafficking mechanism. | Analysis of nucleic acid binding by a recombinant translin-trax complex.
Lluis M, Hoe W, Schleit J, Robertus J., Free PMC Article | 07/12/2010 |
| The TB-RBP-related and -interacting protein Translin-associated factor X was reduced to 50% normal levels in heterozygotes and was absent in TB-RBP-null animals. | Mice deficient for testis-brain RNA-binding protein exhibit a coordinate loss of TRAX, reduced fertility, altered gene expression in the brain, and behavioral changes.
Chennathukuzhi V, Stein JM, Abel T, Donlon S, Yang S, Miller JP, Allman DM, Simmons RA, Hecht NB., Free PMC Article | 01/21/2010 |
| subcellular locations of TB-RBP and TRAX in male germ cells are modulated by the relative ratios of TRAX and TB-RBP | The relative levels of translin-associated factor X (TRAX) and testis brain RNA-binding protein determine their nucleocytoplasmic distribution in male germ cells.
Cho YS, Chennathukuzhi VM, Handel MA, Eppig J, Hecht NB. | 01/21/2010 |
| Trax was found to accumulate in the Golgi complex of mid-late pachytene spermatocytes | Co-localization of Trax and Mea2 in Golgi complex of pachytene spermatocytes in the mouse.
Matsuda M, Kondo M, Kashiwabara S, Yoshihara M, Sutou S, Matsukuma S. | 01/21/2010 |
| TRAX is post-transcriptionally stabilized by TB-RBP and both proteins are needed for normal cell proliferation | Translin-associated factor X is post-transcriptionally regulated by its partner protein TB-RBP, and both are essential for normal cell proliferation.
Yang S, Cho YS, Chennathukuzhi VM, Underkoffler LA, Loomes K, Hecht NB. | 01/21/2010 |