LncRNA KIFAP3-5:1 inhibits epithelial-mesenchymal transition of renal tubular cell through PRRX1 in diabetic nephropathy.
Du L, Lu Y, Wang J, Zheng Y, Li H, Liu Y, Wu X, Zhou J, Wang L, He L, Shi J, Xu L, Li X, Lu Q, Yin X., Free PMC Article

Pathogenic variants in the paired-related homeobox 1 gene (PRRX1) cause craniosynostosis with incomplete penetrance.
Tooze RS, Miller KA, Swagemakers SMA, Calpena E, McGowan SJ, Boute O, Collet C, Johnson D, Laffargue F, de Leeuw N, Morton JV, Noons P, Ockeloen CW, Phipps JM, Tan TY, Timberlake AT, Vanlerberghe C, Wall SA, Weber A, Wilson LC, Zackai EH, Mathijssen IMJ, Twigg SRF, Wilkie AOM., Free PMC Article

A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases.
Nygaard V, Ree AH, Dagenborg VJ, Børresen-Dale AL, Edwin B, Fretland ÅA, Grzyb K, Haugen MH, Mælandsmo GM, Flatmark K., Free PMC Article

Exosomal circPRRX1 functions as a ceRNA for miR-596 to promote the proliferation, migration, invasion, and reduce radiation sensitivity of gastric cancer cells via the upregulation of NF-κB activating protein.
He Y, Zheng L, Yuan M, Fan J, Rong L, Zhan T, Zhang J.

Expression and clinical significance of paired- related homeobox 1 and Smad2 in gastric cancer.
Yang Z, Huang WX, Wang S, Yao JB, Da M.

PRRX1 Is a Novel Prognostic Biomarker and Facilitates Tumor Progression Through Epithelial-Mesenchymal Transition in Uveal Melanoma.
Meng Z, Chen Y, Wu W, Yan B, Zhang L, Chen H, Meng Y, Liang Y, Yao X, Luo J., Free PMC Article

Paired related homeobox 1 attenuates autophagy via acetyl-CoA carboxylase 1-regulated fatty acid metabolism in salivary adenoid cystic carcinoma.
Gao J, Ma K, Zhang L, Li T, Zhao B, Jiang Y., Free PMC Article

PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma-initiating cell properties via DNA methyltransferase 3A.
Tanabe R, Miyazono K, Todo T, Saito N, Iwata C, Komuro A, Sakai S, Raja E, Koinuma D, Morikawa M, Westermark B, Heldin CH., Free PMC Article

PRRX1 Loss-of-Function Mutations Underlying Familial Atrial Fibrillation.
Guo XJ, Qiu XB, Wang J, Guo YH, Yang CX, Li L, Gao RF, Ke ZP, Di RM, Sun YM, Xu YJ, Yang YQ., Free PMC Article

PRRX1-NCOA1-rearranged fibroblastic tumour: a clinicopathological, immunohistochemical and molecular genetic study of six cases of a potentially under-recognised, distinctive mesenchymal tumour.
Dermawan JK, Azzato EM, Jebastin Thangaiah J, Gjorgova-Gjeorgievski S, Rubin BP, Folpe AL, Agaimy A, Fritchie KJ.

Transcription factor paired related homeobox 1 (PRRX1) activates matrix metalloproteinases (MMP)13, which promotes the dextran sulfate sodium-induced inflammation and barrier dysfunction of NCM460 cells.
Zhang X, Ma L, Shen Y, Zhang C, Hou B, Zhou Y., Free PMC Article

RNA binding protein RBMS3 is a common EMT effector that modulates triple-negative breast cancer progression via stabilizing PRRX1 mRNA.
Block CJ, Mitchell AV, Wu L, Glassbrook J, Craig D, Chen W, Dyson G, DeGracia D, Polin L, Ratnam M, Gibson H, Wu G., Free PMC Article

Circular RNA Paired-Related Homeobox 1 Promotes Gastric Carcinoma Cell Progression via Regulating MicroRNA-665/YWHAZ Axis.
Liu W, Hu W, Hou K, Zhu S.

Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y., Free PMC Article

Dysregulated paired related homeobox 1 impacts on hepatocellular carcinoma phenotypes.
Piorońska W, Nwosu ZC, Han M, Büttner M, Ebert MP, Dooley S, Meyer C., Free PMC Article

Activation of COL11A1 by PRRX1 promotes tumor progression and radioresistance in ovarian cancer.
Zhu M, Ye C, Wang J, Yang G, Ying X.

PRRX1 deficiency induces mesenchymal-epithelial transition through PITX2/miR-200-dependent SLUG/CTNNB1 regulation in hepatocellular carcinoma.
Chen W, Wu J, Shi W, Zhang G, Chen X, Ji A, Wang Z, Wu J, Jiang C., Free PMC Article

Paired‑related homeobox 1 overexpression promotes multidrug resistance via PTEN/PI3K/AKT signaling in MCF‑7 breast cancer cells.
Luo H, Cong S, Dong J, Jin L, Jiang D, Wang X, Chen Q, Li F., Free PMC Article

COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1.
Dankel SN, Grytten E, Bjune JI, Nielsen HJ, Dietrich A, Blüher M, Sagen JV, Mellgren G., Free PMC Article

The rs7911488-T allele promotes the growth and metastasis of colorectal cancer through modulating miR-1307/PRRX1.
Yang M, Liu X, Meng F, Zhang Y, Wang M, Chen Y, Guo X, Chen W, Wang W., Free PMC Article

PRRX1 promotes lymph node metastasis of gastric cancer by regulating epithelial-mesenchymal transition.
Yao J, Zhang Y, Xia Y, Zhu C, Wen X, Liu T, Da M., Free PMC Article

Low PRRX1 expression and high ZEB1 expression are significantly correlated with epithelial-mesenchymal transition and tumor angiogenesis in non-small cell lung cancer.
Yang R, Liu Y, Wang Y, Wang X, Ci H, Song C, Wu S., Free PMC Article

Relationship between PRRX1, circulating tumor cells, and clinicopathological parameter in patients with gastric cancer.
Zhang Y, Yao J, Feng J, Wang S, Yang Z, Huang W, Da M.

Exosomal CircPRRX1 Enhances Doxorubicin Resistance in Gastric Cancer by Regulating MiR-3064-5p/PTPN14 Signaling.
Wang S, Ping M, Song B, Guo Y, Li Y, Jia J., Free PMC Article

Pre-metastatic niche triggers SDF-1/CXCR4 axis and promotes organ colonisation by hepatocellular circulating tumour cells via downregulation of Prrx1.
Tang Y, Lu Y, Chen Y, Luo L, Cai L, Peng B, Huang W, Liao H, Zhao L, Pan M., Free PMC Article