| Podocalyxin promotes the formation of compact and chemoresistant cancer spheroids in high grade serous carcinoma. | Podocalyxin promotes the formation of compact and chemoresistant cancer spheroids in high grade serous carcinoma.
Le Tran N, Wang Y, Bilandzic M, Stephens A, Nie G., Free PMC Article | 04/4/2024 |
| Podocalyxin molecular characteristics and endometrial expression: high conservation between humans and macaques but divergence in micedagger. | Podocalyxin molecular characteristics and endometrial expression: high conservation between humans and macaques but divergence in mice†.
Thach B, Samarajeewa N, Li Y, Heng S, Tsai T, Pangestu M, Catt S, Nie G. | 06/25/2022 |
| Podocalyxin promotes an impermeable epithelium and inhibits pro-implantation factors to negatively regulate endometrial receptivity. | Podocalyxin promotes an impermeable epithelium and inhibits pro-implantation factors to negatively regulate endometrial receptivity.
Heng S, Samarajeewa N, Wang Y, Paule SG, Breen J, Nie G., Free PMC Article | 01/29/2022 |
| Atypical focal segmental glomerulosclerosis associated with a new PODXL nonsense variant. | Atypical focal segmental glomerulosclerosis associated with a new PODXL nonsense variant.
Marx D, Caillard S, Olagne J, Moulin B, Hannedouche T, Touchard G, Dupuis A, Gachet C, Molitor A, Bahram S, Carapito R., Free PMC Article | 01/22/2022 |
| CTCF-induced upregulation of LINC01207 promotes gastric cancer progression via miR-1301-3p/PODXL axis. | CTCF-induced upregulation of LINC01207 promotes gastric cancer progression via miR-1301-3p/PODXL axis.
Yu L, Gao Y, Ji B, Feng Z, Li T, Luan W. | 01/22/2022 |
| Effect of fetal growth restriction on urinary podocalyxin levels at birth in preterm neonates. | Effect of fetal growth restriction on urinary podocalyxin levels at birth in preterm neonates.
Siddiqui A, Chawla D, Kaur J, Mahajan V, Jain S. | 01/15/2022 |
| Podocalyxin inhibits human embryo implantation in vitro and luminal podocalyxin in putative receptive endometrium is associated with implantation failure in fertility treatment. | Podocalyxin inhibits human embryo implantation in vitro and luminal podocalyxin in putative receptive endometrium is associated with implantation failure in fertility treatment.
Heng S, Samarajeewa N, Aberkane A, Essahib W, Van de Velde H, Scelwyn M, Hull ML, Vollenhoven B, Rombauts LJ, Nie G. | 12/4/2021 |
| Radiation-Induced Overexpression of TGFbeta and PODXL Contributes to Colorectal Cancer Cell Radioresistance through Enhanced Motility. | Radiation-Induced Overexpression of TGFβ and PODXL Contributes to Colorectal Cancer Cell Radioresistance through Enhanced Motility.
Lee H, Kong JS, Lee SS, Kim A., Free PMC Article | 11/22/2021 |
| Impact of histological response after neoadjuvant therapy on podocalyxin as a prognostic marker in pancreatic cancer. | Impact of histological response after neoadjuvant therapy on podocalyxin as a prognostic marker in pancreatic cancer.
Eurola A, Ristimäki A, Mustonen H, Nurmi AM, Hagström J, Haglund C, Seppänen H., Free PMC Article | 10/30/2021 |
| The transcriptome-wide association search for genes and genetic variants which associate with BMI and gestational weight gain in women with type 1 diabetes. | The transcriptome-wide association search for genes and genetic variants which associate with BMI and gestational weight gain in women with type 1 diabetes.
Ludwig-Słomczyńska AH, Seweryn MT, Kapusta P, Pitera E, Mantaj U, Cyganek K, Gutaj P, Dobrucka Ł, Wender-Ożegowska E, Małecki MT, Wołkow PP., Free PMC Article | 10/2/2021 |
| The role of serum podocalyxin levels in recurrent pregnancy loss. | The role of serum podocalyxin levels in recurrent pregnancy loss.
Yorgancı A, Halici Ozturk F, Hancerliogullari N, Çandar T, Caglar AT, Ozgu-Erdinc AS. | 08/28/2021 |
| [Measurement of PODXL and SCGB1D2 for detecting intraductal papillary mucinous neoplasm]. | [Measurement of PODXL and SCGB1D2 for detecting intraductal papillary mucinous neoplasm].
Taniuchi K, Okabayashi T, Sakaguchi M, Iwata J. | 03/20/2021 |
| PODXL might be a new prognostic biomarker in various cancers: a meta-analysis and sequential verification with TCGA datasets. | PODXL might be a new prognostic biomarker in various cancers: a meta-analysis and sequential verification with TCGA datasets.
He S, Du W, Li M, Yan M, Zheng F., Free PMC Article | 02/2/2021 |
| Kidney transplant monitoring by urinary flow cytometry: Biomarker combination of T cells, renal tubular epithelial cells, and podocalyxin-positive cells detects rejection. | Kidney transplant monitoring by urinary flow cytometry: Biomarker combination of T cells, renal tubular epithelial cells, and podocalyxin-positive cells detects rejection.
Goerlich N, Brand HA, Langhans V, Tesch S, Schachtner T, Koch B, Paliege A, Schneider W, Grützkau A, Reinke P, Enghard P., Free PMC Article | 12/12/2020 |
| Additive clinical impact of epidermal growth factor receptor and podocalyxin-like protein expression in pancreatic and periampullary adenocarcinomas. | Additive clinical impact of epidermal growth factor receptor and podocalyxin-like protein expression in pancreatic and periampullary adenocarcinomas.
Heby M, Karnevi E, Elebro J, Nodin B, Eberhard J, Saukkonen K, Hagström J, Mustonen H, Seppänen H, Haglund C, Jirström K, Larsson AH., Free PMC Article | 12/5/2020 |
| Serum podocalyxin levels are increased in the first trimester in pregnancies that result in SGA infants after 34 weeks of gestation. First-trimester podocalyxin may be useful in screening for SGA infants. | Serum podocalyxin at 11-13 weeks of gestation in the prediction of small for gestational age neonates.
Rolnik DL, Wang Y, Hyett J, Silva Costa FD, Nie G. | 04/25/2020 |
| PODXL role in the pancreatic cancer cell migration.Interaction between PODXL and dynamin-2 promotes migration and metastasis of pancreatic cancer cells by regulating microtubule and focal adhesion dynamics. | A Direct Podocalyxin-Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells.
Wong BS, Shea DJ, Mistriotis P, Tuntithavornwat S, Law RA, Bieber JM, Zheng L, Konstantopoulos K., Free PMC Article | 03/28/2020 |
| the combination of PODXL with ITGB1 and the combination of BCL7B with ITGB1 accurately predicted the postoperative outcomes of pancreatic cancer patients. | Overexpression of PODXL/ITGB1 and BCL7B/ITGB1 accurately predicts unfavorable prognosis compared to the TNM staging system in postoperative pancreatic cancer patients.
Taniuchi K, Furihata M, Naganuma S, Sakaguchi M, Saibara T., Free PMC Article | 02/15/2020 |
| Up-regulated miR-193a, down-regulated WT1/PODXL, elevated amounts of proteinuria/serum creatinine, and declined glomerular filtration rate were implicated as prominent biomarkers for the poor renal survival of idiopathic membranous nephropathy patients. | Application of miR-193a/WT1/PODXL axis to estimate risk and prognosis of idiopathic membranous nephropathy.
Zhang W, Ren Y, Li J., Free PMC Article | 01/18/2020 |
| Results showed that a cancer stem cell gene, PODXL was upregulated especially in DCC low expression meningiomas. [meta-analysis] | Array expression meta-analysis of cancer stem cell genes identifies upregulation of PODXL especially in DCC low expression meningiomas.
Schulten HJ, Hussein D., Free PMC Article | 01/18/2020 |
| PODXL expression was significantly up-regulated in both colorectal cancer (CRC) tissues and cell lines. In vitro experiments showed the knockdown of PODXL reduces CRC tumor growth, metastasis and epithelial-mesenchymal transition, and promoted apoptosis. Moreover, PODXL was predicted and confirmed to be a target of miR-138. | Podocalyxin-like, targeted by miR-138, promotes colorectal cancer cell proliferation, migration, invasion and EMT.
Xu Y, Pan ZG, Shu L, Li QJ. | 01/18/2020 |
| The EMT program can directly enhance the efficiency of extravasation and subsequent metastasis formation through a PODXL-ezrin signaling axis. | Epithelial-Mesenchymal Transition Induces Podocalyxin to Promote Extravasation via Ezrin Signaling.
Fröse J, Chen MB, Hebron KE, Reinhardt F, Hajal C, Zijlstra A, Kamm RD, Weinberg RA., Free PMC Article | 01/11/2020 |
| Study identified that LEA is an approximately 230 kDa podocalyxin-like glycoprotein (PODXL) and found that LEA/PODXL can be secreted in exosomes from colorectal cancer (CRC) cells and peripheral blood which can be an independent predictor of CRC prognosis. | Identification of LEA, a podocalyxin-like glycoprotein, as a predictor for the progression of colorectal cancer.
Yuan D, Chen H, Wang S, Liu F, Cheng Y, Fang J., Free PMC Article | 12/21/2019 |
| Heterozygous PODXL nonsense mutations may have a role in the development of autosomal dominant focal segmental glomerulosclerosis. | First identification of PODXL nonsense mutations in autosomal dominant focal segmental glomerulosclerosis.
Lin FJ, Yao L, Hu XQ, Bian F, Ji G, Jiang GR, Gale DP, Ren HQ. | 10/26/2019 |
| At 11-13 weeks of gestation, serum podocalyxin was significantly elevated in women who subsequently developed preeclampsia. | Serum podocalyxin for early detection of preeclampsia at 11-13 weeks of gestation.
Mansilla M, Wang Y, Hyett J, da Silva Costa F, Nie G. | 09/28/2019 |