| N-acetyltransferase 10 mediates cognitive dysfunction through the acetylation of GABABR1 mRNA in sepsis-associated encephalopathy. | N-acetyltransferase 10 mediates cognitive dysfunction through the acetylation of GABA(B)R1 mRNA in sepsis-associated encephalopathy.
Gao S, Shen R, Li J, Jiang Y, Sun H, Wu X, Li X, Miao C, He M, Wang J, Chen W., | 09/9/2024 |
| GABAB1 receptor knockdown in prefrontal cortex induces behavioral aberrations associated with autism spectrum disorder in mice. | GABA(B1) receptor knockdown in prefrontal cortex induces behavioral aberrations associated with autism spectrum disorder in mice.
Wang X, Zhao Z, Guo J, Mei D, Duan Y, Zhang Y, Gou L. | 10/26/2023 |
| Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABAB1 receptor expression. | Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABA(B1) receptor expression.
Ni T, Zhu L, Wang S, Zhu W, Xue Y, Zhu Y, Ma D, Wang H, Guan F, Chen T., Free PMC Article | 12/10/2022 |
| GABAB receptor signaling in the caudate putamen is involved in binge-like consumption during a high fat diet in mice. | GABA(B) receptor signaling in the caudate putamen is involved in binge-like consumption during a high fat diet in mice.
Sun R, Tsunekawa T, Hirose T, Yaginuma H, Taki K, Mizoguchi A, Miyata T, Kobayashi T, Sugiyama M, Onoue T, Takagi H, Hagiwara D, Ito Y, Iwama S, Suga H, Banno R, Bettler B, Arima H., Free PMC Article | 12/25/2021 |
| Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease. | Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease.
Salazar AM, Leisgang AM, Ortiz AA, Murtishaw AS, Kinney JW. | 09/4/2021 |
| GABAB receptors blockage modulates somatic and aversive manifestations induced by nicotine withdrawal. | GABA(B) receptors blockage modulates somatic and aversive manifestations induced by nicotine withdrawal.
Varani AP, Pedrón VT, Aon AJ, Canero EM, Balerio GN. | 08/14/2021 |
| Reduction in the neuronal surface of post and presynaptic GABAB receptors in the hippocampus in a mouse model of Alzheimer's disease. | Reduction in the neuronal surface of post and presynaptic GABA(B) receptors in the hippocampus in a mouse model of Alzheimer's disease.
Martín-Belmonte A, Aguado C, Alfaro-Ruíz R, Moreno-Martínez AE, de la Ossa L, Martínez-Hernández J, Buisson A, Früh S, Bettler B, Shigemoto R, Fukazawa Y, Luján R., Free PMC Article | 07/10/2021 |
| The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells. | The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells.
Shao L, Elujoba-Bridenstine A, Zink KE, Sanchez LM, Cox BJ, Pollok KE, Sinn AL, Bailey BJ, Sims EC, Cooper SH, Broxmeyer HE, Pajcini KV, Tamplin OJ., Free PMC Article | 07/3/2021 |
| Reelin signaling modulates GABAB receptor function in the neocortex. | Reelin signaling modulates GABA(B) receptor function in the neocortex.
Hamad MIK, Jbara A, Rabaya O, Petrova P, Daoud S, Melliti N, Meseke M, Lutz D, Petrasch-Parwez E, Schwitalla JC, Mark MD, Herlitze S, Reiss G, Herz J, Förster E., Free PMC Article | 05/8/2021 |
| Role of leptin in the regulation of food intake in fasted mice. | Role of leptin in the regulation of food intake in fasted mice.
Ge TT, Yao XX, Zhao FL, Zou XH, Yang W, Cui RJ, Li BJ., Free PMC Article | 05/1/2021 |
| Pianp deficiency links GABAB receptor signaling and hippocampal and cerebellar neuronal cell composition to autism-like behavior. | Pianp deficiency links GABA(B) receptor signaling and hippocampal and cerebellar neuronal cell composition to autism-like behavior.
Winkler M, Biswas S, Berger SM, Küchler M, Preisendörfer L, Choo M, Früh S, Rem PD, Enkel T, Arnold B, Komljenovic D, Sticht C, Goerdt S, Bettler B, von Bohlen Und Halbach O, Bartsch D, Géraud C., Free PMC Article | 03/20/2021 |
| GABAergic input through GABAB receptors is necessary during a perinatal window to shape gene expression of factors critical to reproduction such as Kiss1. | GABAergic input through GABA(B) receptors is necessary during a perinatal window to shape gene expression of factors critical to reproduction such as Kiss1.
Bizzozzero-Hiriart M, Di Giorgio NP, Libertun C, Lux-Lantos V. | 10/31/2020 |
| AJAP1 affects behavioral changes and GABABR1 level in epileptic mice. | AJAP1 affects behavioral changes and GABA(B)R1 level in epileptic mice.
Zhang M, Zhou X, Jiang W, Li M, Zhou R, Zhou S. | 10/31/2020 |
| Multiple failures in the lutenising hormone surge generating system in GABAB1KO female mice. | Multiple failures in the lutenising hormone surge generating system in GABAB1KO female mice.
Di Giorgio NP, Bizzozzero Hiriart M, Surkin PN, López PV, Bourguignon NS, Dorfman VB, Bettler B, Libertun C, Lux-Lantos V. | 10/24/2020 |
| We analyzed the presence and clearance of TAM and its metabolites (N-desmethyl-tamoxifen, 4-hydroxytamoxifen and endoxifen) in brain and serum of mice by liquid chromatographic-high resolution-tandem mass spectrometry (LC-HR-MS/MS) and assessed optimal injection protocols by quantitative RT-PCR of several floxed target genes (p2ry1, gria1, gabbr1 and Rosa26-tdTomato locus). | Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia.
Jahn HM, Kasakow CV, Helfer A, Michely J, Verkhratsky A, Maurer HH, Scheller A, Kirchhoff F., Free PMC Article | 10/5/2019 |
| Loss of GABAB is associated with interhemispheric synaptic inhibition in stroke. | Loss of GABA(B) -mediated interhemispheric synaptic inhibition in stroke periphery.
Kokinovic B, Medini P., Free PMC Article | 09/14/2019 |
| APP/GBR complex formation links presynaptic GBR trafficking to Abeta formation. | Complex formation of APP with GABA(B) receptors links axonal trafficking to amyloidogenic processing.
Dinamarca MC, Raveh A, Schneider A, Fritzius T, Früh S, Rem PD, Stawarski M, Lalanne T, Turecek R, Choo M, Besseyrias V, Bildl W, Bentrop D, Staufenbiel M, Gassmann M, Fakler B, Schwenk J, Bettler B., Free PMC Article | 04/20/2019 |
| These data provide a better framework for understanding the different roles played by GABAB receptors and their effector ion channels in the cerebellar network. | Differential association of GABA(B) receptors with their effector ion channels in Purkinje cells.
Luján R, Aguado C, Ciruela F, Cózar J, Kleindienst D, de la Ossa L, Bettler B, Wickman K, Watanabe M, Shigemoto R, Fukazawa Y., Free PMC Article | 03/2/2019 |
| These data suggest that GABA, acting through both presynaptic GABAA and GABAB receptors, modulate the amplitude and short-term plasticity of excitatory synapses, a result not possible from activation of either receptor type alone | Biphasic modulation of parallel fibre synaptic transmission by co-activation of presynaptic GABAA and GABAB receptors in mice.
Howell RD, Pugh JR., Free PMC Article | 08/19/2017 |
| presynaptic gamma-aminobutyric acid type B receptor deficits contribute to altered neuronal excitability in fragile X syndrome | Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome.
Kang JY, Chadchankar J, Vien TN, Mighdoll MI, Hyde TM, Mather RJ, Deeb TZ, Pangalos MN, Brandon NJ, Dunlop J, Moss SJ., Free PMC Article | 06/24/2017 |
| This study showed that increase dorsal raphe GABA(B1a) expression via epigenetic regulation is associated with abnormal responses to social stimulation such as encounter-induced hyperactivity and aggressive behavior in isolation-reared mice | Epigenetic regulation of dorsal raphe GABA(B1a) associated with isolation-induced abnormal responses to social stimulation in mice.
Araki R, Hiraki Y, Nishida S, Kuramoto N, Matsumoto K, Yabe T. | 09/24/2016 |
| activation of presynaptic hippocampal GABAB receptors is important for acquisition of a learning task and for learning-associated synaptic changes and network dynamics. | Presynaptic GABAB Receptors Regulate Hippocampal Synapses during Associative Learning in Behaving Mice.
Jurado-Parras MT, Delgado-García JM, Sánchez-Campusano R, Gassmann M, Bettler B, Gruart A., Free PMC Article | 07/16/2016 |
| These results suggest a role for GABAB receptor in Fmrp regulation and a potential interest of GABAB receptor signaling in Fragile X syndrome improvement. | GABAB receptor upregulates fragile X mental retardation protein expression in neurons.
Zhang W, Xu C, Tu H, Wang Y, Sun Q, Hu P, Hu Y, Rondard P, Liu J., Free PMC Article | 03/26/2016 |
| Activation of GABA(B) or mGlu2/3 receptors inhibited both evoked presynaptic Ca(2+) transients and striatal field potentials. | Inhibition of presynaptic calcium transients in cortical inputs to the dorsolateral striatum by metabotropic GABA(B) and mGlu2/3 receptors.
Kupferschmidt DA, Lovinger DM., Free PMC Article | 02/13/2016 |
| Embryonic GABA-B receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice. | Embryonic GABA(B) receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice.
Stratton MS, Staros M, Budefeld T, Searcy BT, Nash C, Eitel C, Carbone D, Handa RJ, Majdic G, Tobet SA., Free PMC Article | 11/7/2015 |