| Structural basis of DNA recognition by BEN domain proteins reveals a role for oligomerization in unmethylated DNA selection by BANP. | Structural basis of DNA recognition by BEN domain proteins reveals a role for oligomerization in unmethylated DNA selection by BANP.
Ren J, Wang J, Ren Y, Zhang Y, Wei P, Wang M, Zhang Y, Li M, Yuan C, Gong H, Jiang J, Wang Z., Free PMC Article | 11/5/2024 |
| SMAR1 suppresses the cancer stem cell population via hTERT repression in colorectal cancer cells. | SMAR1 suppresses the cancer stem cell population via hTERT repression in colorectal cancer cells.
Parulekar A, Choksi A, Taye N, Totakura KVS, Firmal P, Kundu GC, Chattopadhyay S. | 07/29/2024 |
| BANP Participates in the Chronic Intermittent Hypoxia-Induced Senescence of Vascular Endothelial Cells by Promoting P53 Phosphorylation and Nuclear Retention. | BANP Participates in the Chronic Intermittent Hypoxia-Induced Senescence of Vascular Endothelial Cells by Promoting P53 Phosphorylation and Nuclear Retention.
Li X, Zhao C, Liu W, Zhu Q, Mu L, Ma C. | 03/6/2024 |
| Nuclear Matrix-associated Protein SMAR1 Attenuated Acute Graft-versus-host Disease by Targeting JAK-STAT Signaling in CD4 + T Cells. | Nuclear Matrix-associated Protein SMAR1 Attenuated Acute Graft-versus-host Disease by Targeting JAK-STAT Signaling in CD4 + T Cells.
Huang Z, Zhang R, Teng Y, Guo J, Zhang H, Wang L, Tang LV, Shi W, Wu Q, Xia L. | 02/23/2024 |
| ZNF471 Interacts with BANP to Reduce Tumour Malignancy by Inactivating PI3K/AKT/mTOR Signalling but is Frequently Silenced by Aberrant Promoter Methylation in Renal Cell Carcinoma. | ZNF471 Interacts with BANP to Reduce Tumour Malignancy by Inactivating PI3K/AKT/mTOR Signalling but is Frequently Silenced by Aberrant Promoter Methylation in Renal Cell Carcinoma.
Wang X, Yao L, Li Z, Zhang J, Ruan M, Mulati Y, Gan Y, Zhang Q., Free PMC Article | 01/9/2024 |
| Structural insights into DNA recognition by the BEN domain of the transcription factor BANP. | Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
Liu K, Zhang J, Xiao Y, Yang A, Song X, Li Y, Chen Y, Hughes TR, Min J., Free PMC Article | 07/6/2023 |
| SMAR1 repression by pluripotency factors and consequent chemoresistance in breast cancer stem-like cells is reversed by aspirin. | SMAR1 repression by pluripotency factors and consequent chemoresistance in breast cancer stem-like cells is reversed by aspirin.
Bhattacharya A, Mukherjee S, Khan P, Banerjee S, Dutta A, Banerjee N, Sengupta D, Basak U, Chakraborty S, Dutta A, Chattopadhyay S, Jana K, Sarkar DK, Chatterjee S, Das T. | 10/30/2021 |
| BANP opens chromatin and activates CpG-island-regulated genes. | BANP opens chromatin and activates CpG-island-regulated genes.
Grand RS, Burger L, Gräwe C, Michael AK, Isbel L, Hess D, Hoerner L, Iesmantavicius V, Durdu S, Pregnolato M, Krebs AR, Smallwood SA, Thomä N, Vermeulen M, Schübeler D. | 08/21/2021 |
| our observations establish that increased expression of SMAR1 in cancers can positively regulate MHC I surface expression thereby leading to higher chances of tumor regression and elimination of cancer cells. | SMAR1 favors immunosurveillance of cancer cells by modulating calnexin and MHC I expression.
Alam A, Taye N, Patel S, Thube M, Mullick J, Shah VK, Pant R, Roychowdhury T, Banerjee N, Chatterjee S, Bhattacharya R, Roy R, Mukhopadhyay A, Mogare D, Chattopadhyay S., Free PMC Article | 04/25/2020 |
| Cdc20 functions as an important negative regulator of SMAR1 in higher grades of cancer | Cdc20 directs proteasome-mediated degradation of the tumor suppressor SMAR1 in higher grades of cancer through the anaphase promoting complex.
Paul D, Ghorai S, Dinesh US, Shetty P, Chattopadhyay S, Santra MK., Free PMC Article | 05/19/2018 |
| Dysregulated circ-BANP appears to have an important role in colorectal cancer cells. | Circular BANP, an upregulated circular RNA that modulates cell proliferation in colorectal cancer.
Zhu M, Xu Y, Chen Y, Yan F. | 04/6/2017 |
| results reveal the complex molecular mechanism underlying SMAR1-mediated signal-dependent and -independent regulation of alternative splicing via Sam68 deacetylation | Nuclear matrix-associated protein SMAR1 regulates alternative splicing via HDAC6-mediated deacetylation of Sam68.
Nakka KK, Chaudhary N, Joshi S, Bhat J, Singh K, Chatterjee S, Malhotra R, De A, Santra MK, Dilworth FJ, Chattopadhyay S., Free PMC Article | 11/21/2015 |
| SMAR1-mediated regulation of repair and apoptosis via a complex crosstalk involving Ku70, HDAC6 and Bax. | SMAR1 coordinates HDAC6-induced deacetylation of Ku70 and dictates cell fate upon irradiation.
Chaudhary N, Nakka KK, Chavali PL, Bhat J, Chatterjee S, Chattopadhyay S., Free PMC Article | 07/25/2015 |
| Data indicate the role of SMAR1 protein in NF-kappaappa B dependent transcriptional regulation of pro-angiogenic chemokine interleukin-8 (IL-8). | Chromatin remodeling protein SMAR1 regulates NF-κB dependent Interleukin-8 transcription in breast cancer.
Malonia SK, Yadav B, Sinha S, Lazennec G, Chattopadhyay S. | 07/25/2015 |
| indicate a crucial role for SMAR1 in restraining breast cancer cell migration and suggest the candidature of this scaffold matrix-associated region-binding protein as a tumor suppressor. | Inhibition of epithelial to mesenchymal transition by E-cadherin up-regulation via repression of slug transcription and inhibition of E-cadherin degradation: dual role of scaffold/matrix attachment region-binding protein 1 (SMAR1) in breast cancer cells.
Adhikary A, Chakraborty S, Mazumdar M, Ghosh S, Mukherjee S, Manna A, Mohanty S, Nakka KK, Joshi S, De A, Chattopadhyay S, Sa G, Das T., Free PMC Article | 02/21/2015 |
| SMAR1 has a role in repressing c-Fos-mediated HPV18 E6 transcription through alteration of chromatin histone deacetylation | Nuclear matrix protein SMAR1 represses c-Fos-mediated HPV18 E6 transcription through alteration of chromatin histone deacetylation.
Chakraborty S, Das K, Saha S, Mazumdar M, Manna A, Chakraborty S, Mukherjee S, Khan P, Adhikary A, Mohanty S, Chattopadhyay S, Biswas SC, Sa G, Das T., Free PMC Article | 12/27/2014 |
| During hemin-induced erythroid differentiation, enhanced expression of SMAR1 negatively correlates with miR-320a expression. | miR-320a regulates erythroid differentiation through MAR binding protein SMAR1.
Mittal SP, Mathai J, Kulkarni AP, Pal JK, Chattopadhyay S. | 08/30/2014 |
| TCF-4, beta-catenin, and SMAR1 tether at the -143-nucleotide site on the HIV LTR to inhibit HIV promoter activity. | Identification of novel T cell factor 4 (TCF-4) binding sites on the HIV long terminal repeat which associate with TCF-4, β-catenin, and SMAR1 to repress HIV transcription.
Henderson LJ, Narasipura SD, Adarichev V, Kashanchi F, Al-Harthi L., Free PMC Article | 11/17/2012 |
| Results indicate that SMAR1 is an important player in p300-p53 regulated DNA damage signalling pathway and can exert its effect on apoptosis in a transcription independent manner. | Chromatin remodelling protein SMAR1 inhibits p53 dependent transactivation by regulating acetyl transferase p300.
Sinha S, Malonia SK, Mittal SP, Mathai J, Pal JK, Chattopadhyay S. | 07/14/2012 |
| multiple roles of nuclear matrix associated protein SMAR1 in regulating various cellular target genes involved in cell growth, apoptosis and tumorigenesis.(REVIEW) | Gene regulation by SMAR1: Role in cellular homeostasis and cancer.
Malonia SK, Sinha S, Lakshminarasimhan P, Singh K, Jalota-Badhwar A, Rampalli S, Kaul-Ghanekar R, Chattopadhyay S. | 03/19/2011 |
| A novel mechanism of regulation of oxidative stress by ATM through modulation of SMAR1-AKR1a4 complex, is proposed. | SMAR1 regulates free radical stress through modulation of AKR1a4 enzyme activity.
Singh S, Sreenath K, Pavithra L, Roy S, Chattopadhyay S. | 10/4/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| SMAR1 plays a central role in coordinating p53 and TGFbeta pathways in human breast cancer. | p53 target gene SMAR1 is dysregulated in breast cancer: its role in cancer cell migration and invasion.
Singh K, Mogare D, Giridharagopalan RO, Gogiraju R, Pande G, Chattopadhyay S., Free PMC Article | 05/3/2010 |
| report Prostaglandin A2 (PGA2) induced binding of HSP70 to a novel site on phi1 SMAR1 5' UTR which stabilizes the wild type transcript and leads to subsequent increase in SMAR1 protein levels. | Heat-shock protein 70 binds to a novel sequence in 5' UTR of tumor suppressor SMAR1 and regulates its mRNA stability upon Prostaglandin A2 treatment.
Pavithra L, Sreenath K, Singh S, Chattopadhyay S. | 05/3/2010 |
| On mild DNA damage, SMAR1 selectively represses BAX and PUMA through binding to the MAR independently of inducing p53 deacetylation through HDAC1. | Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR element.
Sinha S, Malonia SK, Mittal SP, Singh K, Kadreppa S, Kamat R, Mukhopadhyaya R, Pal JK, Chattopadhyay S., Free PMC Article | 03/29/2010 |