| Common and Distinct Genetic Architecture of Age at Diagnosis of Diabetes in South Indian and European Populations. | Common and Distinct Genetic Architecture of Age at Diagnosis of Diabetes in South Indian and European Populations.
Srinivasan S, Liju S, Sathish N, Siddiqui MK, Anjana RM, Pearson ER, Doney ASF, Mohan V, Radha V, Palmer CNA., Free PMC Article | 07/31/2023 |
| Biallelic loss-of-function variants in WDR11 are associated with microcephaly and intellectual disability. | Biallelic loss-of-function variants in WDR11 are associated with microcephaly and intellectual disability.
Haag N, Tan EC, Begemann M, Buschmann L, Kraft F, Holschbach P, Lai AHM, Brett M, Mochida GH, DiTroia S, Pais L, Neil JE, Al-Saffar M, Bastaki L, Walsh CA, Kurth I, Knopp C., Free PMC Article | 03/26/2022 |
| Our study reveals a novel class of ciliopathy caused by WDR11 mutations and suggests that CHH/KS may be a part of the human ciliopathy spectrum. | WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome.
Kim YJ, Osborn DP, Lee JY, Araki M, Araki K, Mohun T, Känsäkoski J, Brandstack N, Kim HT, Miralles F, Kim CH, Brown NA, Kim HG, Martinez-Barbera JP, Ataliotis P, Raivio T, Layman LC, Kim SH., Free PMC Article | 01/19/2019 |
| Data indicate a functional link between adaptor protein complex 1 (AP-1) and the WD repeat protein 11 (WDR11) complex. | The WDR11 complex facilitates the tethering of AP-1-derived vesicles.
Navarro Negredo P, Edgar JR, Manna PT, Antrobus R, Robinson MS., Free PMC Article | 03/17/2018 |
| WDR11 genetic mutation is responsible for the pathophysiology of pituitary stalk interruption syndrome. | Digenic Inheritance of PROKR2 and WDR11 Mutations in Pituitary Stalk Interruption Syndrome.
McCormack SE, Li D, Kim YJ, Lee JY, Kim SH, Rapaport R, Levine MA., Free PMC Article | 10/7/2017 |
| Cellular Protein WDR11 Interacts with Specific Herpes Simplex Virus Proteins at the trans-Golgi Network To Promote Virus Replication. | Cellular Protein WDR11 Interacts with Specific Herpes Simplex Virus Proteins at the trans-Golgi Network To Promote Virus Replication.
Taylor KE, Mossman KL., Free PMC Article | 12/12/2015 |
| WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndrome, causing impaired pubertal development. | WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndrome.
Kim HG, Ahn JW, Kurth I, Ullmann R, Kim HT, Kulharya A, Ha KS, Itokawa Y, Meliciani I, Wenzel W, Lee D, Rosenberger G, Ozata M, Bick DP, Sherins RJ, Nagase T, Tekin M, Kim SH, Kim CH, Ropers HH, Gusella JF, Kalscheuer V, Choi CY, Layman LC., Free PMC Article | 10/30/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A., Free PMC Article | 12/2/2009 |
| Data show that the HTPAPL-WDR11-FGFR2 locus was more susceptible to recombination than to nucleotide substitution. | Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26.
Katoh M, Katoh M. | 01/21/2010 |
| This gene is expressed on chromosome 10p26. | FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26.
Katoh M, Katoh M. | 01/21/2010 |
| Represents a candidate gene for the frequently proposed tumor suppressor gene in 10q25-26, which is involved in tumorigenesis of glial and other tumors showing frequent alterations in the distal 10q region. | A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells.
Chernova OB, Hunyadi A, Malaj E, Pan H, Crooks C, Roe B, Cowell JK. | 10/6/2001 |