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    B2M beta-2-microglobulin [ Homo sapiens (human) ]

    Gene ID: 567, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    beta2-microglobulin induced apoptosis of tumor cells via the ERK signaling pathway by directly interacting with HFE in HER2-overexpressing breast cancer.

    β2-microglobulin induced apoptosis of tumor cells via the ERK signaling pathway by directly interacting with HFE in HER2-overexpressing breast cancer.
    Li K, Chai D, Ren S, Lian X, Shi X, Xu Y, Bao L, Yang S, Liang Y, Li X, Du H., Free PMC Article

    09/19/2024
    Plasma Proteomics Identifies B2M as a Regulator of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction.

    Plasma Proteomics Identifies B2M as a Regulator of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction.
    Jheng JR, DesJardin JT, Chen YY, Huot JR, Bai Y, Cook T, Hibbard LM, Rupp JM, Fisher A, Zhang Y, Duarte JD, Desai AA, Machado RF, Simon MA, Lai YC., Free PMC Article

    07/4/2024
    Association Between Serum GDF15 Concentration and Total Mortality in Community-Dwelling Japanese Older Populations: The Involvement of Renal Dysfunction.

    Association Between Serum GDF15 Concentration and Total Mortality in Community-Dwelling Japanese Older Populations: The Involvement of Renal Dysfunction.
    Fujita Y, Shinkai S, Taniguchi Y, Miura Y, Tanaka M, Ohsawa I, Kitamura A, Ito M.

    09/16/2023
    Differential HLA class I subunit (A, B, C heavy chain and beta2-microglobulin) expression levels in normal tissues.

    Differential HLA class I subunit (A, B, C heavy chain and β(2)-microglobulin) expression levels in normal tissues.
    Ugolini F, Szumera-Ciećkiewicz A, Baroni G, Nesi G, Mandalà M, Ferrone S, Massi D., Free PMC Article

    02/18/2023
    A New Prognostic Index for Extranodal Natural Killer/T-Cell Lymphoma:Incorporation of Serum beta-2 Microglobulin to PINK.

    A New Prognostic Index for Extranodal Natural Killer/T-Cell Lymphoma:Incorporation of Serum β-2 Microglobulin to PINK.
    Kang S, Cho H, Kim S, Lee K, Kang EH, Park JS, Lee YS, Park CS, Go H, Huh J, Ryu JS, Lee SW, Kim SJ, Kim WS, Yoon SE, Ko YH, Suh C., Free PMC Article

    01/21/2023
    Dimers of D76N-beta2-microglobulin display potent antiamyloid aggregation activity.

    Dimers of D76N-β(2)-microglobulin display potent antiamyloid aggregation activity.
    Maya-Martinez R, Xu Y, Guthertz N, Walko M, Karamanos TK, Sobott F, Breeze AL, Radford SE., Free PMC Article

    01/11/2023
    A novel substitution of proline (P32L) destabilises beta2-microglobulin inducing hereditary systemic amyloidosis.

    A novel substitution of proline (P32L) destabilises β2-microglobulin inducing hereditary systemic amyloidosis.
    Prokaeva T, Joshi T, Klimtchuk ES, Gibson VM, Spencer B, Siddiqi O, Nedelkov D, Hu Y, Berk JL, Cuddy SAM, Dasari S, Chiu A, Choate LA, McPhail ED, Cui H, Chen H, Burks EJ, Sanchorawala V, Connors LH.

    01/11/2023
    Correlation between serum beta2-microglobulin level and systemic lupus erythematosus disease activity: A PRISMA-compliant meta-analysis.

    Correlation between serum β2-microglobulin level and systemic lupus erythematosus disease activity: A PRISMA-compliant meta-analysis.
    You T, Lin X, Zhang C, Wang W, Lei M., Free PMC Article

    10/8/2022
    beta2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages.

    β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages.
    Li D, Zhang Q, Li L, Chen K, Yang J, Dixit D, Gimple RC, Ci S, Lu C, Hu L, Gao J, Shan D, Li Y, Zhang J, Shi Z, Gu D, Yuan W, Wu Q, Yang K, Zhao L, Qiu Z, Lv D, Gao W, Yang H, Lin F, Wang Q, Man J, Li C, Tao W, Agnihotri S, Qian X, Shi Y, You Y, Zhang N, Rich JN, Wang X.

    10/8/2022
    beta 2 -Microglobulin Participates in the Development of Vestibular Schwannoma by Regulating Nuclear Factor-kappaB.

    β 2 -Microglobulin Participates in the Development of Vestibular Schwannoma by Regulating Nuclear Factor-κB.
    Jianfei L, Yu Z, Junwei R, Xiang H, Bin W, Ping Z.

    09/24/2022
    Effect of beta2-microglobulin in evaluating the severity and prognosis of brain injury: a clinical study.

    Effect of β2-microglobulin in evaluating the severity and prognosis of brain injury: a clinical study.
    Huo Q, Dong W, Gao Y, Zhang Y, Liu X, Yang L, Nan D, Yang J., Free PMC Article

    09/10/2022
    Impact of beta-2 microglobulin expression on the survival of glioma patients via modulating the tumor immune microenvironment.

    Impact of beta-2 microglobulin expression on the survival of glioma patients via modulating the tumor immune microenvironment.
    Tang F, Zhao YH, Zhang Q, Wei W, Tian SF, Li C, Yao J, Wang ZF, Li ZQ., Free PMC Article

    02/5/2022
    The PRY/SPRY domain of pyrin/TRIM20 interacts with beta2-microglobulin to promote inflammasome formation.

    The PRY/SPRY domain of pyrin/TRIM20 interacts with β(2)-microglobulin to promote inflammasome formation.
    Samukawa S, Yoshimi R, Kirino Y, Nakajima H., Free PMC Article

    01/29/2022
    Urinary beta-2 microglobulin as an early predictive biomarker of acute kidney injury in neonates with perinatal asphyxia.

    Urinary beta-2 microglobulin as an early predictive biomarker of acute kidney injury in neonates with perinatal asphyxia.
    Abdullah, Kadam P, Yachha M, Srivastava G, Pillai A, Pandita A.

    01/22/2022
    Venus flytrap or pas de trois? The dynamics of MHC class I molecules.

    Venus flytrap or pas de trois? The dynamics of MHC class I molecules.
    Jantz-Naeem N, Springer S.

    01/22/2022
    Global Proteotoxicity Caused by Human beta2 Microglobulin Variants Impairs the Unfolded Protein Response in C. elegans.

    Global Proteotoxicity Caused by Human β(2) Microglobulin Variants Impairs the Unfolded Protein Response in C. elegans.
    Good SC, Dewison KM, Radford SE, van Oosten-Hawle P., Free PMC Article

    12/25/2021
    Prognostic Stratification of Patients with Burkitt Lymphoma Using Serum beta2-microglobulin Levels.

    Prognostic Stratification of Patients with Burkitt Lymphoma Using Serum β2-microglobulin Levels.
    Kim HD, Cho H, Kim S, Lee K, Kang EH, Park JS, Park CS, Huh J, Ryu JS, Lee SW, Yoon DH, Kim SJ, Ko YH, Kim WS, Suh C., Free PMC Article

    12/18/2021
    Strong acids induce amyloid fibril formation of beta2-microglobulin via an anion-binding mechanism.

    Strong acids induce amyloid fibril formation of β(2)-microglobulin via an anion-binding mechanism.
    Yamaguchi K, Hasuo K, So M, Ikenaka K, Mochizuki H, Goto Y., Free PMC Article

    12/18/2021
    B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy.

    B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy.
    Zhao Y, Cao Y, Chen Y, Wu L, Hang H, Jiang C, Zhou X., Free PMC Article

    11/13/2021
    Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype.

    Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype.
    de Groen RAL, van Eijk R, Böhringer S, van Wezel T, Raghoo R, Ruano D, Jansen PM, Briaire-de Bruijn I, de Groot FA, Kleiverda K, Te Boome L, Terpstra V, Levenga H, Nicolae A, Posthuma EFM, Focke-Snieders I, Hardi L, den Hartog WCE, Bohmer LH, Hogendoorn PCW, van den Berg A, Diepstra A, Nijland M, Lugtenburg PJ, Kersten MJ, Pals ST, Veelken H, Bovée JVMG, Cleven AHG, Vermaat JSP., Free PMC Article

    11/6/2021
    Elevated cerebrospinal fluid levels of beta-2-microglobulin in patients with Guillain-Barre syndrome and their correlations with clinical features.

    Elevated cerebrospinal fluid levels of beta-2-microglobulin in patients with Guillain-Barré syndrome and their correlations with clinical features.
    Liu MQ, Wang J, Huang CN, Qi Y, Zhang LJ, Yi M, Chang SH, Sun LS, Yang L.

    09/25/2021
    Enhanced accessibility and hydrophobicity of amyloidogenic intermediates of the beta2-microglobulin D76N mutant revealed by high-pressure experiments.

    Enhanced accessibility and hydrophobicity of amyloidogenic intermediates of the β2-microglobulin D76N mutant revealed by high-pressure experiments.
    Sakurai K, Tomiyama R., Free PMC Article

    08/28/2021
    Association of beta-2-microglobulin and cardiovascular events and mortality: A systematic review and meta-analysis.

    Association of beta-2-microglobulin and cardiovascular events and mortality: A systematic review and meta-analysis.
    Shi F, Sun L, Kaptoge S., Free PMC Article

    08/14/2021
    Evaluation of beta-2 microglobulin, erythropoietin and tobacco use in polycythemic cases.

    Evaluation of beta-2 microglobulin, erythropoietin and tobacco use in polycythemic cases.
    Mahe K, Couturaud F, Kerspern H, Chauveau A, Ianotto JC.

    08/14/2021
    Respiratory ss-2-Microglobulin exerts pH dependent antimicrobial activity.

    Respiratory ß-2-Microglobulin exerts pH dependent antimicrobial activity.
    Holch A, Bauer R, Olari LR, Rodriguez AA, Ständker L, Preising N, Karacan M, Wiese S, Walther P, Ruiz-Blanco YB, Sanchez-Garcia E, Schumann C, Münch J, Spellerberg B., Free PMC Article

    07/24/2021
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