| Lactate-upregulated ARG2 expression induces cellular senescence in fibroblast-like synoviocytes of osteoarthritis via activating the mTOR/S6K1 signaling pathway. | Lactate-upregulated ARG2 expression induces cellular senescence in fibroblast-like synoviocytes of osteoarthritis via activating the mTOR/S6K1 signaling pathway.
Huang Y, Yue S, Yan Z, Liu Y, Qiao J, Zhang M, Dong Y, Zheng J. | 10/17/2024 |
| BCAT1 alleviates early brain injury by inhibiting ferroptosis through PI3K/AKT/mTOR/GPX4 pathway after subarachnoid hemorrhage. | BCAT1 alleviates early brain injury by inhibiting ferroptosis through PI3K/AKT/mTOR/GPX4 pathway after subarachnoid hemorrhage.
Liu N, Li C, Yan C, Yan HC, Jin BX, Yang HR, Jiang GY, Gong HD, Li JY, Ma SJ, Liu HL, Gao C. | 08/29/2024 |
| Overexpression of long noncoding RNA DUXAP8 inhibits ER-phagy through activating AKT/mTOR signaling and contributes to preeclampsia. | Overexpression of long noncoding RNA DUXAP8 inhibits ER-phagy through activating AKT/mTOR signaling and contributes to preeclampsia.
Wei XH, Liao LY, Yin YX, Xu Q, Xie SS, Liu M, Gao LB, Chen HQ, Zhou R., Free PMC Article | 08/15/2024 |
| TRPM7 Mediates Neuropathic Pain by Activating mTOR Signaling in Astrocytes after Spinal Cord Injury in Rats. | TRPM7 Mediates Neuropathic Pain by Activating mTOR Signaling in Astrocytes after Spinal Cord Injury in Rats.
Kim IY, Park CS, Seo KJ, Lee JY, Yune TY. | 07/22/2024 |
| Novel protein C6ORF120 promotes liver fibrosis by activating hepatic stellate cells through the PI3K/Akt/mTOR pathway. | Novel protein C6ORF120 promotes liver fibrosis by activating hepatic stellate cells through the PI3K/Akt/mTOR pathway.
Wang X, Liu H, Wang Y, Wang P, Yi Y, Lin Y, Li X. | 07/18/2024 |
| The involvement of Akt, mTOR, and S6K in the in vivo effect of IGF-1 on the regulation of rat cardiac Na[+]/K[+]-ATPase. | The involvement of Akt, mTOR, and S6K in the in vivo effect of IGF-1 on the regulation of rat cardiac Na(+)/K(+)-ATPase.
Banjac K, Obradovic M, Zafirovic S, Essack M, Gluvic Z, Sunderic M, Nedic O, Isenovic ER. | 04/22/2024 |
| mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms. | mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms.
Ali Y, Gomez-Sanchez CE, Plonczynski M, Naray-Fejes-Toth A, Fejes-Toth G, Gomez-Sanchez EP., Free PMC Article | 02/27/2024 |
| TRPM7 Mediates BSCB Disruption After Spinal Cord Injury by Regulating the mTOR/JMJD3 Axis in Rats. | TRPM7 Mediates BSCB Disruption After Spinal Cord Injury by Regulating the mTOR/JMJD3 Axis in Rats.
Park CS, Lee JY, Seo KJ, Kim IY, Ju BG, Yune TY. | 02/16/2024 |
| Silencing PKM2 Attenuates Brain Injury Induced by Status Epilepticus by Inhibiting the AKT/mTOR Pathway and the NLRP3 Inflammasome. | Silencing PKM2 Attenuates Brain Injury Induced by Status Epilepticus by Inhibiting the AKT/mTOR Pathway and the NLRP3 Inflammasome.
Cui X, Jia R, Zhao R, Ma N, Jiang F. | 01/10/2024 |
| mTOR/ULK1 signaling axis mediated ultrashort wave regulation of autophagy to alleviate diabetic kidney disease. | mTOR/ULK1 signaling axis mediated ultrashort wave regulation of autophagy to alleviate diabetic kidney disease.
Yan Y, Yu S, Fan Y. | 11/30/2023 |
| Bilirubin impacts microglial autophagy via the Akt-mTOR signaling pathway. | Bilirubin impacts microglial autophagy via the Akt-mTOR signaling pathway.
Li L, Li S, Pan Z, Zhang Y, Hua Z. | 11/14/2023 |
| HIF-1alpha-PPARgamma-mTORC1 signaling pathway-mediated autophagy induces inflammatory response in pancreatic cells in rats with hyperlipidemic acute pancreatitis. | HIF-1α-PPARγ-mTORC1 signaling pathway-mediated autophagy induces inflammatory response in pancreatic cells in rats with hyperlipidemic acute pancreatitis.
Ma Y, Li X, Liu Z, Xue X, Wang Y, Ma Y. | 09/26/2023 |
| Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate. | Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate.
Li Y, Zhou Y, Liu D, Wang Z, Qiu J, Zhang J, Chen P, Zeng G, Guo Y, Wang X, DiSanto ME, Zhang X., Free PMC Article | 08/30/2023 |
| mTOR Inhibitors Modulate the Physical Properties of 3D Spheroids Derived from H9c2 Cells. | mTOR Inhibitors Modulate the Physical Properties of 3D Spheroids Derived from H9c2 Cells.
Watanabe M, Yano T, Sato T, Umetsu A, Higashide M, Furuhashi M, Ohguro H., Free PMC Article | 08/19/2023 |
| The Regulation of the AMPK/mTOR Axis Mitigates Tendon Stem/Progenitor Cell Senescence and Delays Tendon Aging. | The Regulation of the AMPK/mTOR Axis Mitigates Tendon Stem/Progenitor Cell Senescence and Delays Tendon Aging.
Dai G, Li Y, Zhang M, Lu P, Zhang Y, Wang H, Shi L, Cao M, Shen R, Rui Y. | 07/25/2023 |
| [KLF15/mTOR related proteins involved in effect of aerobic interval training on improving skeletal muscle lesions in rats with type 2 diabetes]. | [KLF15/mTOR related proteins involved in effect of aerobic interval training on improving skeletal muscle lesions in rats with type 2 diabetes].
Liao ZX, Huang L, Zhu HZ, Zhu MJ. | 06/15/2023 |
| Vitamin B6 Deficiency Induces Autism-Like Behaviors in Rats by Regulating mTOR-Mediated Autophagy in the Hippocampus. | Vitamin B6 Deficiency Induces Autism-Like Behaviors in Rats by Regulating mTOR-Mediated Autophagy in the Hippocampus.
Chen L, Li J, Liu X, Zhao Z, Jin Y, Fu Y, Zhou A, Wang C, Zhou Y., Free PMC Article | 05/23/2023 |
| The Mechanism of Aerobic Exercise Regulating the PI3K/Akt-mTOR Signaling Pathway Intervenes in Hippocampal Neuronal Apoptosis in Vascular Dementia Rats. | The Mechanism of Aerobic Exercise Regulating the PI3K/Akt-mTOR Signaling Pathway Intervenes in Hippocampal Neuronal Apoptosis in Vascular Dementia Rats.
Gao L, Liu F, Liu R., Free PMC Article | 02/16/2023 |
| Fidgetin impacts axonal growth and branching in a local mTOR signal dependent manner. | Fidgetin impacts axonal growth and branching in a local mTOR signal dependent manner.
Ma C, Wang J, Tu Q, Wu R, Lai X, Lin G, Dong Z, Guan T, Qiang L, Liu Y, Liu M. | 02/4/2023 |
| Role of the mTOR Signalling Pathway During Extracellular Acidosis in Tumour Cells. | Role of the mTOR Signalling Pathway During Extracellular Acidosis in Tumour Cells.
Wolff M, Rauschner M, Reime S, Riemann A, Thews O. | 01/11/2023 |
| GDH promotes isoprenaline-induced cardiac hypertrophy by activating mTOR signaling via elevation of alpha-ketoglutarate level. | GDH promotes isoprenaline-induced cardiac hypertrophy by activating mTOR signaling via elevation of α-ketoglutarate level.
Lin ZR, Li ZZ, Cao YJ, Yu WJ, Ye JT, Liu PQ. | 10/22/2022 |
| mTOR and HDAC2 are simultaneously activated during electrically induced kindling of seizures. | mTOR and HDAC2 are simultaneously activated during electrically induced kindling of seizures.
Chmielewska N, Wawer A, Osuch B, Maciejak P, Szyndler J. | 08/27/2022 |
| A rat study model of depression-driven chronic prostatitis by modulating the PI3K/Akt/mTOR network. | A rat study model of depression-driven chronic prostatitis by modulating the PI3K/Akt/mTOR network.
Feng JL, Hou D, Zhao C, Bao BH, Huang SY, Deng S, Meng FC, Zhao Q, Wang B, Li HS, Wang JS. | 08/6/2022 |
| The mechanism behind BAF60c in myocardial metabolism in rats with heart failure is through the PGC1alpha-PPARalpha-mTOR signaling pathway. | The mechanism behind BAF60c in myocardial metabolism in rats with heart failure is through the PGC1α-PPARα-mTOR signaling pathway.
Chen Q, Chen L, Jian J, Li J, Zhang X. | 04/16/2022 |
| PPARbeta/delta accelerates bone regeneration in diabetic mellitus by enhancing AMPK/mTOR pathway-mediated autophagy. | PPARβ/δ accelerates bone regeneration in diabetic mellitus by enhancing AMPK/mTOR pathway-mediated autophagy.
Chen M, Jing D, Ye R, Yi J, Zhao Z., Free PMC Article | 04/2/2022 |