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    BACH1 BTB domain and CNC homolog 1 [ Homo sapiens (human) ]

    Gene ID: 571, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Her2 amplification, Rel-A, and Bach1 can influence APOBEC3A expression in breast cancer cells.

    Her2 amplification, Rel-A, and Bach1 can influence APOBEC3A expression in breast cancer cells.
    Dennis M, Hurley A, Bray N, Cordero C, Ilagan J, Mertz TM, Roberts SA., Free PMC Article

    10/31/2024
    Loss of BACH1 improves osteogenic differentiation in glucocorticoid-induced hBMSCs through restoring autophagy.

    Loss of BACH1 improves osteogenic differentiation in glucocorticoid-induced hBMSCs through restoring autophagy.
    Xiao S, Li G, Tan M, Liu W, Li W., Free PMC Article

    08/29/2024
    Role of BACH1 in multiple myeloma.

    Role of BACH1 in multiple myeloma.
    Chen Y, Zeng Z, Chen J.

    08/27/2024
    TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22.

    TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22.
    Liu L, Matsumoto M, Watanabe-Matsui M, Nakagawa T, Nagasawa Y, Pang J, Callens BKK, Muto A, Ochiai K, Takekawa H, Alam M, Nishizawa H, Shirouzu M, Shima H, Nakayama K, Igarashi K., Free PMC Article

    05/20/2024
    BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17.

    BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17.
    He Y, Guo J, Yu Y, Jin J, Jiang Q, Li Q, Ma S, Pan Q, Lin J, Jiang N, Ma J, Li Y, Hou Y, Zhi X, Jiang L, Qu L, Osto E, Wang X, Wei X, Meng D.

    01/5/2024
    Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.

    Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
    Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F., Free PMC Article

    12/1/2023
    Antioxidants stimulate BACH1-dependent tumor angiogenesis.

    Antioxidants stimulate BACH1-dependent tumor angiogenesis.
    Wang T, Dong Y, Huang Z, Zhang G, Zhao Y, Yao H, Hu J, Tüksammel E, Cai H, Liang N, Xu X, Yang X, Schmidt S, Qiao X, Schlisio S, Strömblad S, Qian H, Jiang C, Treuter E, Bergo MO., Free PMC Article

    11/1/2023
    BACH1 promotes lung adenocarcinoma cell metastasis through transcriptional activation of ITGA2.

    BACH1 promotes lung adenocarcinoma cell metastasis through transcriptional activation of ITGA2.
    Chen Y, Jin L, Ma Y, Liu Y, Zhu Q, Huang Y, Feng W., Free PMC Article

    09/8/2023
    Ferroptosis model system by the re-expression of BACH1.

    Ferroptosis model system by the re-expression of BACH1.
    Irikura R, Nishizawa H, Nakajima K, Yamanaka M, Chen G, Tanaka K, Onodera M, Matsumoto M, Igarashi K.

    08/31/2023
    Chemotherapy-induced exosomal circBACH1 promotes breast cancer resistance and stemness via miR-217/G3BP2 signaling pathway.

    Chemotherapy-induced exosomal circBACH1 promotes breast cancer resistance and stemness via miR-217/G3BP2 signaling pathway.
    Xia W, Chen W, Ni C, Meng X, Wu J, Yang Q, Tang H, Yuan H, Fang S., Free PMC Article

    07/24/2023
    Evaluation of Bach1 mRNA expression in patients with chronic kidney disease: A preliminary study.

    Evaluation of Bach1 mRNA expression in patients with chronic kidney disease: A preliminary study.
    Mafra D, Alvarenga L, Ribeiro M, Baptista BG, Fanton S, Paiva BR, Trugilho L, Kemp JA, Alves-Ribeiro M, Cardozo LFMF.

    07/21/2023
    BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility.

    BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility.
    Guo J, Qiu J, Jia M, Li Q, Wei X, Li L, Pan Q, Jin J, Ge F, Ma S, He Y, Lin J, Li Y, Ma J, Jiang N, Zhi X, Jiang L, Zhang J, Osto E, Jing Q, Wang X, Meng D., Free PMC Article

    05/24/2023
    Thioredoxin facilitates hepatocellular carcinoma stemness and metastasis by increasing BACH1 stability to activate the AKT/mTOR pathway.

    Thioredoxin facilitates hepatocellular carcinoma stemness and metastasis by increasing BACH1 stability to activate the AKT/mTOR pathway.
    Wang C, Zhang L, Cao M, Fu Z, Wang H, Zhang S, Zhu K, Hou Z, Cui J, Yue P, Guo H, Zhang T.

    05/8/2023
    Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.

    Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
    Chen T, Zhang X, Ding X, Feng J, Zhang X, Xie D, Wang X., Free PMC Article

    04/6/2023
    FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

    FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.
    Zhu XN, Wei YS, Yang Q, Liu HR, Zhi Z, Zhu D, Xia L, Hong DL, Yu Y, Chen GQ., Free PMC Article

    02/15/2023
    BACH1 promotes clear cell renal cell carcinoma progression by upregulating oxidative stress-related tumorigenicity.

    BACH1 promotes clear cell renal cell carcinoma progression by upregulating oxidative stress-related tumorigenicity.
    Takemoto K, Kobatake K, Miura K, Fukushima T, Babasaki T, Miyamoto S, Sekino Y, Kitano H, Goto K, Ikeda K, Hieda K, Hayashi T, Hinata N, Kaminuma O., Free PMC Article

    02/11/2023
    BACH1-induced ferroptosis drives lymphatic metastasis by repressing the biosynthesis of monounsaturated fatty acids.

    BACH1-induced ferroptosis drives lymphatic metastasis by repressing the biosynthesis of monounsaturated fatty acids.
    Xie X, Tian L, Zhao Y, Liu F, Dai S, Gu X, Ye Y, Zhou L, Liu X, Sun Y, Zhao X., Free PMC Article

    02/11/2023
    BACH1 regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells.

    BACH1 regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells.
    Liu C, Yu J, Liu B, Liu M, Song G, Zhu L, Peng B., Free PMC Article

    12/3/2022
    Iron in Cancer Progression: Does BACH1 Promote Metastasis by Altering Iron Homeostasis?

    Iron in Cancer Progression: Does BACH1 Promote Metastasis by Altering Iron Homeostasis?
    Igarashi K, Nishizawa H, Matsumoto M.

    11/5/2022
    CircRNA circBACH1 facilitates hepatitis B virus replication and hepatoma development by regulating the miR-200a-3p/MAP3K2 axis.

    CircRNA circBACH1 facilitates hepatitis B virus replication and hepatoma development by regulating the miR-200a-3p/MAP3K2 axis.
    Du N, Li K, Wang Y, Song B, Zhou X, Duan S.

    10/29/2022
    BTB domain and CNC homolog 1 promotes glioma invasion mainly through regulating extracellular matrix and increases ferroptosis sensitivity.

    BTB domain and CNC homolog 1 promotes glioma invasion mainly through regulating extracellular matrix and increases ferroptosis sensitivity.
    Cong Z, Yuan F, Wang H, Cai X, Zhu J, Tang T, Zhang L, Han Y, Ma C.

    10/22/2022
    The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma.

    The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma.
    Liu T, Wang Y, Wang Y, Cheung SK, Or PM, Wong CW, Guan J, Li Z, Yang W, Tu Y, Wang J, Ho WL, Gu H, Cheng AS, Tsui SK, Chan AM.

    10/22/2022
    Isoflurane Promotes Cell Proliferation, Invasion, and Migration by Regulating BACH1 and miR-375 in Prostate Cancer Cells In Vitro.

    Isoflurane Promotes Cell Proliferation, Invasion, and Migration by Regulating BACH1 and miR-375 in Prostate Cancer Cells In Vitro.
    Zheng J, Chen G, Li T, He X, Luo Y, Yang K.

    06/11/2022
    LINC00665 interacts with BACH1 to activate Wnt1 and mediates the M2 polarization of tumor-associated macrophages in GC.

    LINC00665 interacts with BACH1 to activate Wnt1 and mediates the M2 polarization of tumor-associated macrophages in GC.
    Yang B, Su K, Sha G, Bai Q, Sun G, Chen H, Xie H, Jiang X.

    05/21/2022
    Overexpression of BACH1 mediated by IGF2 facilitates hepatocellular carcinoma growth and metastasis via IGF1R and PTK2.

    Overexpression of BACH1 mediated by IGF2 facilitates hepatocellular carcinoma growth and metastasis via IGF1R and PTK2.
    Xie M, Sun M, Ji X, Li D, Chen X, Zhang B, Huang W, Zhang T, Wang Y, Tian D, Xia L., Free PMC Article

    05/7/2022
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