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    MIR492 microRNA 492 [ Homo sapiens (human) ]

    Gene ID: 574449, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    hsa_circ_0129047 Upregulates LYVE1 to Inhibit Hepatocellular Carcinoma Progression by Sponging miR-492.

    hsa_circ_0129047 Upregulates LYVE1 to Inhibit Hepatocellular Carcinoma Progression by Sponging miR-492.
    Feng Z, Wu J., Free PMC Article

    11/3/2023
    NamiRNA-enhancer network of miR-492 activates the NR2C1-TGF-beta/Smad3 pathway to promote epithelial-mesenchymal transition of pancreatic cancer.

    NamiRNA-enhancer network of miR-492 activates the NR2C1-TGF-β/Smad3 pathway to promote epithelial-mesenchymal transition of pancreatic cancer.
    Liu S, He X, Di Y, Li Q, Li F, Ma Y, Chen L, Gao Y, Xu J, Yang S, Xu L, Corpe C, Ling Y, Zhang X, Xu J, Yu W, Wang J.

    05/30/2023
    The immunogenic involvement of miRNA-492 in mycoplasma pneumoniae infection in pediatric patients.

    The immunogenic involvement of miRNA-492 in mycoplasma pneumoniae infection in pediatric patients.
    Jia Z, Sun Q, Zheng Y, Xu J, Wang Y., Free PMC Article

    03/17/2023
    Association of miRNA-492 rs2289030 G>C and miRNA-938 rs2505901 T>C Gene Polymorphisms with Biliary Atresia Susceptibility.

    Association of miRNA-492 rs2289030 G>C and miRNA-938 rs2505901 T>C Gene Polymorphisms with Biliary Atresia Susceptibility.
    Su L, Tian Y, Fu M, Zhang RZ, Ou XF, Xia HM, Li RZ.

    04/30/2022
    Association between miR-492 rs2289030 G>C and susceptibility to Hirschsprung disease in southern Chinese children.

    Association between miR-492 rs2289030 G>C and susceptibility to Hirschsprung disease in southern Chinese children.
    Zheng Y, Liu Y, Wang M, He Q, Xie X, Lu L, Zhong W., Free PMC Article

    07/17/2021
    miR-492 promotes chemoresistance to CDDP and metastasis by targeting inhibiting DNMT3B and induces stemness in gastric cancer.

    miR-492 promotes chemoresistance to CDDP and metastasis by targeting inhibiting DNMT3B and induces stemness in gastric cancer.
    Wu S, Xie J, Shi H, Wang ZW., Free PMC Article

    03/27/2021
    Effects of miR-492 on migration, invasion, EMT and prognosis in ovarian cancer by targeting SOX7.

    Effects of miR-492 on migration, invasion, EMT and prognosis in ovarian cancer by targeting SOX7.
    Wang Z, Liu Y, Wang M, Zhao J.

    02/13/2021
    The overexpression of LATS2 repressed the growth and invasion of ACHN and 786-O cells. circ_0001368 upregulated the LATS2 expression and suppressed ACHN and 786-O cell growth and invasion by sponging miR-492.

    Circular RNA circ_0001368 inhibited growth and invasion in renal cell carcinoma by sponging miR-492 and targeting LATS2.
    Chen L, Wu D, Ding T.

    08/1/2020
    study demonstrated that miR-492 was over-expressed in Prostate Cancer and exerted tumor-promoting function in PCa cells via repressing SOCS2 expression.

    MiR-492 exerts tumor-promoting function in prostate cancer through repressing SOCS2 expression.
    Shi LP, Liang M, Li FF, Li T, Lai DH, Xie QL, Yin YF, Liu YF.

    07/18/2020
    In conclusion, miR492 inhibition may impede the malignant behaviour of retinoblastoma (RB) by directly targeting LATS2. Therefore, targeting this miRNA may be an effective therapeutic method for treating patients with RB.

    Inhibition of microRNA‑492 attenuates cell proliferation and invasion in retinoblastoma via directly targeting LATS2.
    Sun Z, Zhang A, Zhang L.

    05/25/2019
    miR-492 significantly enhances cell proliferation, anchorage-independent growth, migration and invasion of hepatoblastoma cells. High miR-492 expression correlates with high-risk or aggressive tumours and further bears potential for predicting reduced event-free survival. The study identified miR-492 and its target CD44 as regulators of a number of biological features important for malignancy and metastasis.

    MiR-492 regulates metastatic properties of hepatoblastoma via CD44.
    von Frowein J, Hauck SM, Kappler R, Pagel P, Fleischmann KK, Magg T, Cairo S, Roscher A, von Schweinitz D, Schmid I.

    04/13/2019
    Diabetic Cardiovascular Complications are associated with decreased levels of miR-492 suggesting that MIR-492 may be novel biomarkers.

    Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms.
    Petrie JR, Guzik TJ, Touyz RM., Free PMC Article

    03/2/2019
    p21-activated kinase (PAK7) was identified as the putative target of miR492 in osteosarcoma (OS), and we further found a significantly inverse correlation between PAK7 and miR492 in OS specimens.

    MicroRNA-492 overexpression exerts suppressive effects on the progression of osteosarcoma by targeting PAK7.
    Song X, Xie Y, Liu Y, Shao M, Yang W.

    04/21/2018
    miR-492 may be involved in the regulation of OK antigen expression on red blood cells with the BSG rs8259 TT genotype.

    [The role of miR-492 in the regulation of OK blood group antigen expression on red blood cells].
    Ye L, Wang C, Yang Q, Zhu Z.

    03/17/2018
    Data show that tissue inhibitor of metalloproteinase 2 (TIMP2) is a direct target of miR-492 that modulates cervical cancer cell invasion.

    MicroRNA-492 overexpression involves in cell proliferation, migration, and radiotherapy response of cervical squamous cell carcinomas.
    Liu M, An J, Huang M, Wang L, Tu B, Song Y, Ma K, Wang Y, Wang S, Zhu H, Xu N, Wu L.

    12/23/2017
    The potential use of miR-492 rs2289030 as a prognostic marker .

    miR-492G>C polymorphism (rs2289030) is associated with overall survival of hepatocellular carcinoma patients.
    Yu G, Xiao Q, Ma XP, Chen X, Shi Z, Zhang LY, Chen H, Zhang P, Ding DL, Huang HX, Saiyin H, Chen TY, Lu PX, Wang NJ, Yu H, Sun J, Conran C, Zheng SL, Xu J, Yu L, Jiang DK.

    02/18/2017
    The miR-492/CD147 axis might play an essential role in the Oxaliplatin resistance of colon cancer cells.

    MiR-492 is functionally involved in Oxaliplatin resistance in colon cancer cells LS174T via its regulating the expression of CD147.
    Peng L, Zhu H, Wang J, Sui H, Zhang H, Jin C, Li L, Xu T, Miao R.

    02/20/2016
    the present study provided novel insights into the potential mechanisms involved in Clear cell renal cell carcinoma and it is hypothesized that miR-492 may become a promising therapeutic agent in the treatment of Clear cell renal cell carcinoma

    Upregulation of microRNA-492 induced by epigenetic drug treatment inhibits the malignant phenotype of clear cell renal cell carcinoma in vitro.
    Wu A, Wu K, Li M, Bao L, Shen X, Li S, Li J, Yang Z.

    01/16/2016
    miR-492 contributes to insulin resistance and endothelial dysfunction induced by high glucose, via directly downregulating resistin expression.

    MicroRNA-492 reverses high glucose-induced insulin resistance in HUVEC cells through targeting resistin.
    Ying C, Sui-Xin L, Kang-Ling X, Wen-Liang Z, Lei D, Yuan L, Fan Z, Chen Z., Free PMC Article

    11/28/2015
    Data indicate that elevated miR-492 expression in prostate tumors that resulted in diminished myeloid zinc-finger 1 (MZF-1) and ferroportin (FPN).

    Myeloid zinc-finger 1 (MZF-1) suppresses prostate tumor growth through enforcing ferroportin-conducted iron egress.
    Chen Y, Zhang Z, Yang K, Du J, Xu Y, Liu S.

    10/17/2015
    Ectopic expression of miR-492 led to downregulation of SOX7 protein.

    MiR-492 contributes to cell proliferation and cell cycle of human breast cancer cells by suppressing SOX7 expression.
    Shen F, Cai WS, Feng Z, Li JL, Chen JW, Cao J, Xu B.

    06/20/2015
    miR-492 exerts a potent anti-angiogenic activity in endothelial cells.

    MiR-492 impairs the angiogenic potential of endothelial cells.
    Patella F, Leucci E, Evangelista M, Parker B, Wen J, Mercatanti A, Rizzo M, Chiavacci E, Lund AH, Rainaldi G., Free PMC Article

    05/3/2014
    study suggests that miR-492 may physiologically suppress BSG expression and the BSG rs8259 polymorphism is associated with decreased psoriasis susceptibility through affecting miR-492 binding.

    A miRNA-492 binding-site polymorphism in BSG (basigin) confers risk to psoriasis in central south Chinese population.
    Wu LS, Li FF, Sun LD, Li D, Su J, Kuang YH, Chen G, Chen XP, Chen X.

    01/21/2012
    miR-492 can originate from the coding sequence of the HB marker gene keratin 19 (KRT19)

    MicroRNA-492 is processed from the keratin 19 gene and up-regulated in metastatic hepatoblastoma.
    von Frowein J, Pagel P, Kappler R, von Schweinitz D, Roscher A, Schmid I.

    05/14/2011
    Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)See all PubMed (3) articles12/2/2009
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