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    MIR493 microRNA 493 [ Homo sapiens (human) ]

    Gene ID: 574450, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Exosomal miR-493 suppresses MAD2L1 and induces chemoresistance to intraperitoneal paclitaxel therapy in gastric cancer patients with peritoneal metastasis.

    Exosomal miR-493 suppresses MAD2L1 and induces chemoresistance to intraperitoneal paclitaxel therapy in gastric cancer patients with peritoneal metastasis.
    Makinoya M, Miyatani K, Matsumi Y, Sakano Y, Shimizu S, Shishido Y, Hanaki T, Kihara K, Matsunaga T, Yamamoto M, Tokuyasu N, Takano S, Sakamoto T, Hasegawa T, Saito H, Nakayama Y, Osaki M, Okada F, Fujiwara Y., Free PMC Article

    05/22/2024
    Expression and significant roles of the lncRNA NEAT1/miR-493-5p/Rab27A axis in ulcerative colitis.

    Expression and significant roles of the lncRNA NEAT1/miR-493-5p/Rab27A axis in ulcerative colitis.
    Wang H, Teng J, Wang M, Zhang Y, Liu X, Liu Z., Free PMC Article

    05/31/2023
    Cancer-associated fibroblasts promote tumor cell growth via miR-493-5p in intrahepatic cholangiocarcinoma.

    Cancer-associated fibroblasts promote tumor cell growth via miR-493-5p in intrahepatic cholangiocarcinoma.
    Toshida K, Itoh S, Harada N, Morinaga A, Yugawa K, Tomiyama T, Kosai-Fujimoto Y, Tomino T, Kurihara T, Nagao Y, Morita K, Oda Y, Yoshizumi T., Free PMC Article

    03/13/2023
    Propofol-Induced miR-493-3p Inhibits Growth and Invasion of Gastric Cancer through Suppression of DKK1-Mediated Wnt/beta-Catenin Signaling Activation.

    Propofol-Induced miR-493-3p Inhibits Growth and Invasion of Gastric Cancer through Suppression of DKK1-Mediated Wnt/β-Catenin Signaling Activation.
    Zhan K, Song X, Zhang Q, Yang J, Lu S., Free PMC Article

    02/13/2023
    LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway.

    LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway.
    Sharma U, Kaur Rana M, Singh K, Jain A.

    02/4/2023
    Tumor-suppressive MEG3 induces microRNA-493-5p expression to reduce arabinocytosine chemoresistance of acute myeloid leukemia cells by downregulating the METTL3/MYC axis.

    Tumor-suppressive MEG3 induces microRNA-493-5p expression to reduce arabinocytosine chemoresistance of acute myeloid leukemia cells by downregulating the METTL3/MYC axis.
    Wang A, Chen Y, Shi L, Li M, Li L, Wang S, Wang C., Free PMC Article

    07/2/2022
    Overexpression of miR-493-3p suppresses ovarian cancer cell proliferation, migration and invasion through downregulating DPY30.

    Overexpression of miR-493-3p suppresses ovarian cancer cell proliferation, migration and invasion through downregulating DPY30.
    Liu Q, Yang H, Hua H.

    06/18/2022
    ILF3-AS1 promotes the aerobic glycolysis and proliferation of melanoma cells by regulating miR-493-5p/PDK1 pathway.

    ILF3-AS1 promotes the aerobic glycolysis and proliferation of melanoma cells by regulating miR-493-5p/PDK1 pathway.
    Huang WQ, Zhuang QR, He ZJ.

    04/23/2022
    Circ-CSPP1 knockdown suppresses hepatocellular carcinoma progression through miR-493-5p releasing-mediated HMGB1 downregulation.

    Circ-CSPP1 knockdown suppresses hepatocellular carcinoma progression through miR-493-5p releasing-mediated HMGB1 downregulation.
    Yang G, Xu Q, Wan Y, Zhang L, Wang L, Meng F.

    04/9/2022
    SNHG1 functions as an oncogenic lncRNA and promotes osteosarcoma progression by up-regulating S100A6 via miR-493-5p.

    SNHG1 functions as an oncogenic lncRNA and promotes osteosarcoma progression by up-regulating S100A6 via miR-493-5p.
    Liu Q, Luo J, Wang H, Zhang L, Jin G., Free PMC Article

    04/2/2022
    MiR-493-5p inhibits the malignant development of gliomas via suppressing E2F3-mediated dysfunctions of P53 and PI3K/AKT pathways.

    MiR-493-5p inhibits the malignant development of gliomas via suppressing E2F3-mediated dysfunctions of P53 and PI3K/AKT pathways.
    Liu H, Li Z, Sun H.

    03/12/2022
    Circular RNA circPRKDC promotes tumorigenesis of gastric cancer via modulating insulin receptor substrate 2 (IRS2) and mediating microRNA-493-5p.

    Circular RNA circPRKDC promotes tumorigenesis of gastric cancer via modulating insulin receptor substrate 2 (IRS2) and mediating microRNA-493-5p.
    Liu Z, Wang Y, Ding Y., Free PMC Article

    02/26/2022
    Circ_PIP5K1A regulates cisplatin resistance and malignant progression in non-small cell lung cancer cells and xenograft murine model via depending on miR-493-5p/ROCK1 axis.

    Circ_PIP5K1A regulates cisplatin resistance and malignant progression in non-small cell lung cancer cells and xenograft murine model via depending on miR-493-5p/ROCK1 axis.
    Feng N, Guo Z, Wu X, Tian Y, Li Y, Geng Y, Yu Y., Free PMC Article

    02/12/2022
    miR-493 by regulating of c-Jun targets Wnt5a/PD-L1-inducing esophageal cancer cell development.

    miR-493 by regulating of c-Jun targets Wnt5a/PD-L1-inducing esophageal cancer cell development.
    Bian W, Li Y, Zhu H, Gao S, Niu R, Wang C, Zhang H, Qin X, Li S., Free PMC Article

    12/25/2021
    Long coding RNA CCAT2 enhances the proliferation and epithelial-mesenchymal transition of cervical carcinoma cells via the microRNA-493-5p/CREB1 axis.

    Long coding RNA CCAT2 enhances the proliferation and epithelial-mesenchymal transition of cervical carcinoma cells via the microRNA-493-5p/CREB1 axis.
    Wang J, Liu Y, Cai H, Jiang H, Li W, Shi Y., Free PMC Article

    12/18/2021
    Silencing of Long Non-Coding RNA FGD5-AS1 Inhibits the Progression of Non-Small Cell Lung Cancer by Regulating the miR-493-5p/DDX5 Axis.

    Silencing of Long Non-Coding RNA FGD5-AS1 Inhibits the Progression of Non-Small Cell Lung Cancer by Regulating the miR-493-5p/DDX5 Axis.
    Cui F, Luo P, Bai Y, Meng J., Free PMC Article

    11/27/2021
    Long non-coding RNA NR2F1-AS1 promoted neuroblastoma progression through miR-493-5p/TRIM2 axis.

    Long non-coding RNA NR2F1-AS1 promoted neuroblastoma progression through miR-493-5p/TRIM2 axis.
    Liu L, Zhao H, He HH, Huang J, Xu YY, Li XL, Wu Y, Wang J, Zhu YB.

    07/3/2021
    Lung cancerassociated transcript 1 facilitates tumorigenesis in laryngeal squamous cell carcinoma through the targeted inhibition of miR493.

    Lung cancer‑associated transcript 1 facilitates tumorigenesis in laryngeal squamous cell carcinoma through the targeted inhibition of miR‑493.
    Zhao Z, Xing Y, Liu Y, Jing S., Free PMC Article

    04/17/2021
    MicroRNA-493-5p suppresses colorectal cancer progression via the PI3K-Akt-FoxO3a signaling pathway.

    MicroRNA-493-5p suppresses colorectal cancer progression via the PI3K-Akt-FoxO3a signaling pathway.
    Cui FC, Chen Y, Wu XY, Hu M, Qin WS.

    04/3/2021
    MiR-493 Induces Cytotoxic Autophagy in Prostate Cancer Cells through Regulation on PHLPP2.

    MiR-493 Induces Cytotoxic Autophagy in Prostate Cancer Cells through Regulation on PHLPP2.
    Deng J, Ma M, Jiang W, Zheng L, Cui S.

    01/9/2021
    Long noncoding RNA GAS6-AS2 sponges microRNA-493, thereby enhancing the malignant characteristics of breast cancer cells via upregulation of FUT4.

    Long noncoding RNA GAS6-AS2 sponges microRNA-493, thereby enhancing the malignant characteristics of breast cancer cells via upregulation of FUT4.
    Li W, Jin X, Zhao Y, Dai J, Cai Y.

    12/19/2020
    LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p.

    LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p.
    Wang XY, Wang L, Xu PC, Huang FJ, Jian X, Wei ZC, Chen YQ.

    10/24/2020
    Molecular Mechanisms and Therapeutic Potential of miR-493 in Cancer.

    Molecular Mechanisms and Therapeutic Potential of miR-493 in Cancer.
    Huang L, Huang L, Li Z, Wei Q.

    09/19/2020
    miR-493-5p mediated part of its tumor-suppressor activity by abrogating overexpression of insulin-like growth factor 2 (IGF2) and the IGF2-derived intronic oncomir miR-483-3p in hepatocellular carcinoma cells characterized by IGF2 loss of imprinting.

    MEG3-derived miR-493-5p overcomes the oncogenic feature of IGF2-miR-483 loss of imprinting in hepatic cancer cells.
    Gailhouste L, Liew LC, Yasukawa K, Hatada I, Tanaka Y, Kato T, Nakagama H, Ochiya T., Free PMC Article

    08/12/2020
    MYCN expression levels were inversely correlated with miR-493-5p in tumor tissues.

    MicroRNA-493-5p-mediated repression of the MYCN oncogene inhibits hepatic cancer cell growth and invasion.
    Yasukawa K, Liew LC, Hagiwara K, Hironaka-Mitsuhashi A, Qin XY, Furutani Y, Tanaka Y, Nakagama H, Kojima S, Kato T, Ochiya T, Gailhouste L., Free PMC Article

    03/21/2020
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