U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    MIR512-1 microRNA 512-1 [ Homo sapiens (human) ]

    Gene ID: 574458, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    miR-200c-3p, miR-222-5p, and miR-512-3p Constitute a Biomarker Signature of Sorafenib Effectiveness in Advanced Hepatocellular Carcinoma.

    miR-200c-3p, miR-222-5p, and miR-512-3p Constitute a Biomarker Signature of Sorafenib Effectiveness in Advanced Hepatocellular Carcinoma.
    de la Cruz-Ojeda P, Schmid T, Boix L, Moreno M, Sapena V, Praena-Fernández JM, Castell FJ, Falcón-Pérez JM, Reig M, Brüne B, Gómez-Bravo MA, Giráldez Á, Bruix J, Ferrer MT, Muntané J., Free PMC Article

    10/8/2022
    Downregulation of microRNA-512-3p enhances the viability and suppresses the apoptosis of vascular endothelial cells, alleviates autophagy and endoplasmic reticulum stress as well as represses atherosclerotic lesions in atherosclerosis by adjusting spliced/unspliced ratio of X-box binding protein 1 (XBP-1S/XBP-1U).

    Downregulation of microRNA-512-3p enhances the viability and suppresses the apoptosis of vascular endothelial cells, alleviates autophagy and endoplasmic reticulum stress as well as represses atherosclerotic lesions in atherosclerosis by adjusting spliced/unspliced ratio of X-box binding protein 1 (XBP-1S/XBP-1U).
    Ge P, Gao M, Du J, Yu J, Zhang L., Free PMC Article

    02/19/2022
    Hsa_circ_0005576 promotes osimertinib resistance through the miR-512-5p/IGF1R axis in lung adenocarcinoma cells.

    Hsa_circ_0005576 promotes osimertinib resistance through the miR-512-5p/IGF1R axis in lung adenocarcinoma cells.
    Liu S, Jiang Z, Xiao P, Li X, Chen Y, Tang H, Chai Y, Liu Y, Zhu Z, Xie Q, He W, Ma Y, Jin L, Feng W., Free PMC Article

    01/15/2022
    LncRNA NCK1-AS1 promotes non-small cell lung cancer progression via regulating miR-512-5p/p21 axis.

    LncRNA NCK1-AS1 promotes non-small cell lung cancer progression via regulating miR-512-5p/p21 axis.
    Luo X, Zhou J, Quan L, Liang Y, Huang P, Chen F, Liu S.

    08/28/2021
    miR-512-3p Overcomes Resistance to Cisplatin in Retinoblastoma by Promoting Apoptosis Induced by Endoplasmic Reticulum Stress.

    miR-512-3p Overcomes Resistance to Cisplatin in Retinoblastoma by Promoting Apoptosis Induced by Endoplasmic Reticulum Stress.
    Kong M, Han Y, Zhao Y, Zhang H., Free PMC Article

    05/1/2021
    AFAP1-AS1 regulates miR-512-3p, so as to realize the regulation effect on the proliferation.

    Long non-coding RNA AFAP1-AS1 promotes proliferation and invasion in prostate cancer via targeting miR-512-3p.
    Wang K, Sun H, Sun T, Qu H, Xie Q, Lv H, Hu B.

    01/11/2020
    PURPOSE: To perform serum microRNA expression profiling to identify members of chromosome 19 miRNA cluster involved in preeclampsia development. METHODS: Serum chromosome 19 miRNA cluster microRNA expression profiling was evaluated at 12, 16, and 20 gestational weeks and at the time of preeclampsia diagnosis, in women who developed preeclampsia (WWD-PE; n = 16) and controls (n = 18) using TaqMan low density array p

    Circulating levels of specific members of chromosome 19 microRNA cluster are associated with preeclampsia development.
    Martinez-Fierro ML, Garza-Veloz I, Gutierrez-Arteaga C, Delgado-Enciso I, Barbosa-Cisneros OY, Flores-Morales V, Hernandez-Delgadillo GP, Rocha-Pizaña MR, Rodriguez-Sanchez IP, Badillo-Almaraz JI, Ortiz-Rodriguez JM, Castañeda-Miranda R, Solis-Sanchez LO, Ortiz-Castro Y.

    03/30/2019
    Reduced miR-512 and the elevated expression of its targets cFLIP and MCL1 localize to neurons with hyperphosphorylated Tau protein in Alzheimer disease.

    Reduced miR-512 and the Elevated Expression of Its Targets cFLIP and MCL1 Localize to Neurons With Hyperphosphorylated Tau Protein in Alzheimer Disease.
    Mezache L, Mikhail M, Garofalo M, Nuovo GJ.

    07/30/2016
    miR-512-5p suppresses tumor growth by targeting TERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo.

    miR-512-5p suppresses tumor growth by targeting hTERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo.
    Li J, Lei H, Xu Y, Tao ZZ., Free PMC Article

    05/14/2016
    Data (including data from micro-dissected trophoblasts and trophoblastic BeWo cell line) suggest that microRNA-512-3p participates in placental function by targeting PPP3R1, encoding a regulatory subunit of calcineurin B.

    Placenta-specific miRNA (miR-512-3p) targets PPP3R1 encoding the calcineurin B regulatory subunit in BeWo cells.
    Kurashina R, Kikuchi K, Iwaki J, Yoshitake H, Takeshita T, Takizawa T.

    04/11/2015
    two stem cell microRNA gene clusters C19MC (miR-512-5p, miR-517a, and miR-519a)and miR-371-3 are activated by specific chromosomal rearrangements in a subgroup of thyroid adenomas.

    The two stem cell microRNA gene clusters C19MC and miR-371-3 are activated by specific chromosomal rearrangements in a subgroup of thyroid adenomas.
    Rippe V, Dittberner L, Lorenz VN, Drieschner N, Nimzyk R, Sendt W, Junker K, Belge G, Bullerdiek J., Free PMC Article

    02/3/2012
    Disclose a novel regulatory mechanism inHepG2 cells where down-regulation of c-FLIP by miR-512-3p contributed to taxol-induced apoptosis.

    Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells.
    Chen F, Zhu HH, Zhou LF, Wu SS, Wang J, Chen Z.

    10/29/2010
    Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells. (microRNA-512-5p)

    Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.
    Saito Y, Suzuki H, Tsugawa H, Nakagawa I, Matsuzaki J, Kanai Y, Hibi T.

    10/27/2010
    firstprevious page of 1 nextlast